# Definium Therapeutics, Inc.: overview

DFTX · Nasdaq · CIK 1813814 · [Healthcare](/sectors/healthcare.md) · fiscal year ends Dec 31

Pages: [Overview](/companies/dftx.md) · [Financials](/companies/dftx/financials.md) · [Filings](/companies/dftx/filings.md) · [Insiders](/companies/dftx/insiders.md)

Revenue is not reported in this company’s XBRL financial statements.

## Last eight quarters

| Line item | Unit | Q3 FY2024 (2024-09-30) | Q4 FY2024 (2024-12-31) | Q1 FY2025 (2025-03-31) | Q2 FY2025 (2025-06-30) | Q3 FY2025 (2025-09-30) | Q4 FY2025 (2025-12-31) | Q1 FY2026 (2026-03-31) | Q2 FY2026 (2026-06-30) |
| --- | --- | ---: | ---: | ---: | ---: | ---: | ---: | ---: | ---: |
| Revenue | $ | not reported | not reported | not reported | not reported | not reported | not reported | not reported | not reported |
| Gross margin | % | not reported | not reported | not reported | not reported | not reported | not reported | not reported | not reported |
| Operating margin | % | not reported | not reported | not reported | not reported | not reported | not reported | not reported | not reported |
| Net margin | % | not reported | not reported | not reported | not reported | not reported | not reported | not reported | not reported |
| Diluted EPS | $ per share | [(0.27)](/filings/0001193125-25-269596.md) | not reported | [(0.35)](/filings/0001193125-26-211989.md) | [(0.50)](/filings/0001193125-26-338066.md) | [(0.78)](/filings/0001193125-25-269596.md) | not reported | [(0.71)](/filings/0001193125-26-211989.md) | [(1.44)](/filings/0001193125-26-338066.md) |
| Free cash flow | $ | not reported | not reported | not reported | not reported | not reported | not reported | not reported | not reported |

- Revenue. XBRL not reported.
- Gross margin (gross profit / revenue). XBRL not reported.
- Operating margin (operating income / revenue). XBRL Operating income: us-gaap:OperatingIncomeLoss. Derived values: 12-month figure less the 9-month figure.
- Net margin (net income / revenue). XBRL Net income: us-gaap:NetIncomeLoss. Derived values: 12-month figure less the 9-month figure.
- Diluted EPS. XBRL Diluted EPS: us-gaap:EarningsPerShareDiluted.
- Free cash flow (operating cash flow − capital expenditure). XBRL Operating cash flow: us-gaap:NetCashProvidedByUsedInOperatingActivities. Derived values: 9-month figure less the 6-month figure; 12-month figure less the 9-month figure; 6-month figure less the 3-month figure.

## Last five fiscal years

| Line item | Unit | FY2021 (2021-12-31) | FY2022 (2022-12-31) | FY2023 (2023-12-31) | FY2024 (2024-12-31) | FY2025 (2025-12-31) |
| --- | --- | ---: | ---: | ---: | ---: | ---: |
| Revenue | $ | not reported | not reported | not reported | not reported | not reported |
| Gross margin | % | not reported | not reported | not reported | not reported | not reported |
| Operating margin | % | not reported | not reported | not reported | not reported | not reported |
| Net margin | % | not reported | not reported | not reported | not reported | not reported |
| Diluted EPS | $ per share | [(3.40)](/filings/0000950170-23-007053.md) | [(1.84)](/filings/0000950170-24-021656.md) | [(2.44)](/filings/0000950170-25-034176.md) | [(1.54)](/filings/0001193125-26-076742.md) | [(2.06)](/filings/0001193125-26-076742.md) |
| Free cash flow | $ | not reported | not reported | not reported | not reported | not reported |

- Revenue. XBRL not reported.
- Gross margin (gross profit / revenue). XBRL not reported.
- Operating margin (operating income / revenue). XBRL Operating income: us-gaap:OperatingIncomeLoss.
- Net margin (net income / revenue). XBRL Net income: us-gaap:NetIncomeLoss.
- Diluted EPS. XBRL Diluted EPS: us-gaap:EarningsPerShareDiluted.
- Free cash flow (operating cash flow − capital expenditure). XBRL Operating cash flow: us-gaap:NetCashProvidedByUsedInOperatingActivities.

Each value links to the filing it came from. d marks a derived value. A ratio is not reported when any input is missing.

## Insider purchases and sales

The last 20 open-market transactions on Form 4 (codes P and S). Reported price is as stated on the form, not a market price. [All insider transactions](/companies/dftx/insiders.md)

None in coverage.

## Funds that report holding it

From each manager’s latest Form 13F, largest reported value first. Reported value is as filed: filing data, not a price. [All funds](/funds.md)

| Fund | Quarter ended | Reported value | Shares | Put or call | Change on the quarter before |
| --- | --- | ---: | ---: | --- | --- |
| [BlackRock, Inc.](/funds/2012383.md) | 2026-06-30 | $528.4m | 11,232,834 |  | Added +2,752,604 |
| [Avoro Capital Advisors LLC](/funds/1633313.md) | 2026-06-30 | $338.2m | 7,188,888 |  | Added +2,188,888 |
| [Driehaus Capital Management LLC](/funds/938206.md) | 2026-06-30 | $322.0m | 6,845,276 |  | Added +933,387 |
| [Jupiter Topco LLC](/funds/2146052.md) | 2026-06-30 | $264.0m | 5,615,645 |  | Not compared |
| [Capital World Investors](/funds/1422849.md) | 2026-06-30 | $252.5m | 5,367,723 |  | New +5,367,723 |
| [FMR LLC](/funds/315066.md) | 2026-06-30 | $223.6m | 4,752,921 |  | Added +2,943,311 |
| [GEODE CAPITAL MANAGEMENT, LLC](/funds/1214717.md) | 2026-06-30 | $171.5m | 3,644,813 |  | Added +1,149,414 |
| [STATE STREET CORP](/funds/93751.md) | 2026-06-30 | $144.2m | 3,065,390 |  | Added +593,517 |
| [Capital International Investors](/funds/1562230.md) | 2026-06-30 | $139.4m | 2,963,410 |  | New +2,963,410 |
| [Octagon Capital Advisors LP](/funds/1839435.md) | 2026-06-30 | $138.8m | 2,950,000 |  | Added +510,000 |

## Recent filings

[All 500 filings](/companies/dftx/filings.md)

| Filed | Accepted | Form | What it is | Accession |
| --- | --- | --- | --- | --- |
| 2026-09-14 | 08:02 ET | [8-K](/filings/0001104659-26-107275.md) | 7.01 Regulation FD disclosure; 8.01 Other events; 9.01 Financial statements and exhibits | 0001104659-26-107275 |
| 2026-09-08 | 08:00 ET | [8-K](/filings/0001193125-26-384403.md) | 8.01 Other events; 9.01 Financial statements and exhibits | 0001193125-26-384403 |
| 2026-08-12 | 08:05 ET | [8-K](/filings/0001104659-26-094528.md) | 7.01 Regulation FD disclosure; 8.01 Other events; 9.01 Financial statements and exhibits | 0001104659-26-094528 |
| 2026-08-06 | 16:16 ET | [10-Q](/filings/0001193125-26-338066.md) | Quarterly report, period 2026-06-30 | 0001193125-26-338066 |
| 2026-08-06 | 16:10 ET | [8-K](/filings/0001193125-26-338006.md) | 2.02 Results of operations; 9.01 Financial statements and exhibits | 0001193125-26-338006 |
| 2026-06-24 | 17:14 ET | [8-K](/filings/0001104659-26-077354.md) | 1.01 Entry into a material agreement; 8.01 Other events; 9.01 Financial statements and exhibits | 0001104659-26-077354 |
| 2026-06-22 | 08:01 ET | [8-K](/filings/0001104659-26-076091.md) | 7.01 Regulation FD disclosure; 8.01 Other events; 9.01 Financial statements and exhibits | 0001104659-26-076091 |
| 2026-06-12 | 16:30 ET | [8-K](/filings/0001193125-26-269549.md) | 5.02 Departure or appointment of officers or directors; 5.07 Shareholder vote results; 9.01 Financial statements and exhibits | 0001193125-26-269549 |
| 2026-05-19 | 07:30 ET | [8-K](/filings/0001193125-26-229657.md) | 8.01 Other events; 9.01 Financial statements and exhibits | 0001193125-26-229657 |
| 2026-05-12 | 08:15 ET | [8-K](/filings/0001193125-26-218251.md) | 8.01 Other events; 9.01 Financial statements and exhibits | 0001193125-26-218251 |

## Latest annual report

[Form 10-K for the fiscal year ended Dec 31, 2025](/filings/0001193125-26-076742.md), filed Feb 26, 2026.

## Forecast league

Not in this season’s league. [This season’s league](/leagues.md)

## About the filer

- CIK: 1813814
- Tickers: DFTX
- Exchange: Nasdaq
- SIC code: 2833 Medicinal Chemicals & Botanical Products
- State of incorporation: A1
- Filer category: <br>Emerging growth company

Source: SEC EDGAR, XBRL company facts, the filing index and Forms 4. Last ingested by Listed: Oct 24, 2026, 15:48 ET. No prices; not investment advice.
