# Polaryx Therapeutics, Inc.: overview

PLYX · Nasdaq · CIK 2075320 · [Healthcare](/sectors/healthcare.md) · fiscal year ends Dec 31

Pages: [Overview](/companies/plyx.md) · [Financials](/companies/plyx/financials.md) · [Filings](/companies/plyx/filings.md) · [Insiders](/companies/plyx/insiders.md)

Revenue is not reported in this company’s XBRL financial statements.

## Last eight quarters

| Line item | Unit | period not labelled (2025-03-31) | period not labelled (2025-06-30) | Q1 FY2026 (2026-03-31) | Q2 FY2026 (2026-06-30) |
| --- | --- | ---: | ---: | ---: | ---: |
| Revenue | $ | not reported | not reported | not reported | not reported |
| Gross margin | % | not reported | not reported | not reported | not reported |
| Operating margin | % | not reported | not reported | not reported | not reported |
| Net margin | % | not reported | not reported | not reported | not reported |
| Diluted EPS | $ per share | [(0.11)](/filings/0001213900-26-056973.md) | [(0.02)](/filings/0001213900-26-089118.md) | [(0.05)](/filings/0001213900-26-056973.md) | [(0.03)](/filings/0001213900-26-089118.md) |
| Free cash flow | $ | not reported | not reported | not reported | not reported |

- Revenue. XBRL not reported.
- Gross margin (gross profit / revenue). XBRL not reported.
- Operating margin (operating income / revenue). XBRL Operating income: us-gaap:OperatingIncomeLoss.
- Net margin (net income / revenue). XBRL Net income: us-gaap:NetIncomeLoss.
- Diluted EPS. XBRL Diluted EPS: us-gaap:EarningsPerShareDiluted.
- Free cash flow (operating cash flow − capital expenditure). XBRL Operating cash flow: us-gaap:NetCashProvidedByUsedInOperatingActivities. Derived values: 6-month figure less the 3-month figure.

## Last five fiscal years

| Line item | Unit | FY (2024-12-31) | FY2025 (2025-12-31) |
| --- | --- | ---: | ---: |
| Revenue | $ | not reported | not reported |
| Gross margin | % | not reported | not reported |
| Operating margin | % | not reported | not reported |
| Net margin | % | not reported | not reported |
| Diluted EPS | $ per share | [(0.89)](/filings/0001213900-26-033064.md) | [(0.20)](/filings/0001213900-26-033064.md) |
| Free cash flow | $ | not reported | not reported |

- Revenue. XBRL not reported.
- Gross margin (gross profit / revenue). XBRL not reported.
- Operating margin (operating income / revenue). XBRL Operating income: us-gaap:OperatingIncomeLoss.
- Net margin (net income / revenue). XBRL Net income: us-gaap:NetIncomeLoss.
- Diluted EPS. XBRL Diluted EPS: us-gaap:EarningsPerShareDiluted.
- Free cash flow (operating cash flow − capital expenditure). XBRL Operating cash flow: us-gaap:NetCashProvidedByUsedInOperatingActivities.

Each value links to the filing it came from. d marks a derived value. A ratio is not reported when any input is missing.

## Insider purchases and sales

The last 20 open-market transactions on Form 4 (codes P and S). Reported price is as stated on the form, not a market price. [All insider transactions](/companies/plyx/insiders.md)

None in coverage.

## Funds that report holding it

From each manager’s latest Form 13F, largest reported value first. Reported value is as filed: filing data, not a price. [All funds](/funds.md)

| Fund | Quarter ended | Reported value | Shares | Put or call | Change on the quarter before |
| --- | --- | ---: | ---: | --- | --- |
| [VANGUARD CAPITAL MANAGEMENT LLC](/funds/2100119.md) | 2026-06-30 | $4.4m | 1,657,872 |  | Reduced −516 |
| [GEODE CAPITAL MANAGEMENT, LLC](/funds/1214717.md) | 2026-06-30 | $455.1k | 170,998 |  | Added +325 |
| [VANGUARD FIDUCIARY TRUST CO](/funds/933478.md) | 2026-06-30 | $279.5k | 105,072 |  | Added +516 |
| [STATE STREET CORP](/funds/93751.md) | 2026-06-30 | $154.6k | 58,104 |  | Unchanged |
| [BlackRock, Inc.](/funds/2012383.md) | 2026-06-30 | $109.1k | 41,012 |  | Unchanged |
| [JANE STREET GROUP, LLC](/funds/1595888.md) | 2026-06-30 | $83.6k | 31,441 |  | New +31,441 |
| [NORTHERN TRUST CORP](/funds/73124.md) | 2026-06-30 | $74.4k | 27,987 |  | Unchanged |
| [Allworth Financial LP](/funds/1555170.md) | 2026-06-30 | $20.6k | 7,727 |  | New +7,727 |
| [Vanguard Global Advisers, LLC](/funds/1811242.md) | 2026-06-30 | $16.8k | 6,318 |  | Unchanged |
| [Tower Research Capital LLC (TRC)](/funds/1533421.md) | 2026-06-30 | $8.0k | 3,002 |  | Added +1,221 |

## Recent filings

[All 35 filings](/companies/plyx/filings.md)

| Filed | Accepted | Form | What it is | Accession |
| --- | --- | --- | --- | --- |
| 2026-09-14 | 19:59 ET | [8-K](/filings/0001213900-26-099416.md) | 5.07 Shareholder vote results | 0001213900-26-099416 |
| 2026-09-01 | 16:30 ET | [8-K](/filings/0001213900-26-096235.md) | 7.01 Regulation FD disclosure; 8.01 Other events; 9.01 Financial statements and exhibits | 0001213900-26-096235 |
| 2026-08-13 | 16:15 ET | [10-Q](/filings/0001213900-26-089118.md) | Quarterly report, period 2026-06-30 | 0001213900-26-089118 |
| 2026-07-28 | 17:00 ET | [DEF 14A](/filings/0001213900-26-082339.md) | Proxy statement, period 2026-09-10 | 0001213900-26-082339 |
| 2026-07-21 | 16:30 ET | [8-K](/filings/0001213900-26-080041.md) | 5.02 Departure or appointment of officers or directors | 0001213900-26-080041 |
| 2026-07-17 | 08:00 ET | [8-K](/filings/0001213900-26-078912.md) | 5.08 Item not in the standard list; 8.01 Other events | 0001213900-26-078912 |
| 2026-05-28 | 16:31 ET | [8-K](/filings/0001213900-26-062155.md) | 1.01 Entry into a material agreement; 3.02 Unregistered sale of equity; 7.01 Regulation FD disclosure; 9.01 Financial statements and exhibits | 0001213900-26-062155 |
| 2026-05-15 | 20:01 ET | [10-Q](/filings/0001213900-26-056973.md) | Quarterly report, period 2026-03-31 | 0001213900-26-056973 |
| 2026-03-24 | 17:48 ET | [10-K](/filings/0001213900-26-033064.md) | Annual report, period 2025-12-31 | 0001213900-26-033064 |
| 2026-02-05 | 16:05 ET | [SCHEDULE 13D](/filings/0001213900-26-012759.md) | Ownership report, active investor | 0001213900-26-012759 |

## Latest annual report

[Form 10-K for the fiscal year ended Dec 31, 2025](/filings/0001213900-26-033064.md), filed Mar 24, 2026.

## Forecast league

Not in this season’s league. [This season’s league](/leagues.md)

## About the filer

- CIK: 2075320
- Tickers: PLYX
- Exchange: Nasdaq
- SIC code: 2834 Pharmaceutical Preparations
- State of incorporation: WY
- Filer category: <br>Emerging growth company

Source: SEC EDGAR, XBRL company facts, the filing index and Forms 4. Last ingested by Listed: Oct 24, 2026, 15:51 ET. No prices; not investment advice.
