# Senti Biosciences Holdings, Inc.: overview

SNTI · Nasdaq · CIK 1854270 · [Healthcare](/sectors/healthcare.md) · fiscal year ends Dec 31

Pages: [Overview](/companies/snti.md) · [Financials](/companies/snti/financials.md) · [Filings](/companies/snti/filings.md) · [Insiders](/companies/snti/insiders.md)

Latest reported revenue: [$17.0k](/filings/0001628280-26-057110.md) for Q2 FY2026, three months to 2026-06-30, from the 10-Q filed Aug 14, 2026 (XBRL us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax, accession 0001628280-26-057110).

## Last eight quarters

| Line item | Unit | Q3 FY2024 (2024-09-30) | Q4 FY2024 (2024-12-31) | Q1 FY2025 (2025-03-31) | Q2 FY2025 (2025-06-30) | Q3 FY2025 (2025-09-30) | Q4 FY2025 (2025-12-31) | Q1 FY2026 (2026-03-31) | Q2 FY2026 (2026-06-30) |
| --- | --- | ---: | ---: | ---: | ---: | ---: | ---: | ---: | ---: |
| Revenue | $m | [0.0](/filings/0001854270-24-000116.md) | [0.0 d](/filings/0001628280-26-021580.md) | [0.0](/filings/0001628280-26-035126.md) | [0.0](/filings/0001628280-26-057110.md) | not reported | not reported | [0.0](/filings/0001628280-26-035126.md) | [0.0](/filings/0001628280-26-057110.md) |
| Gross margin | % | not reported | not reported | not reported | not reported | not reported | not reported | not reported | not reported |
| Operating margin | % | not reported | not reported | not reported | not reported | not reported | not reported | [(28850.0%)](/filings/0001628280-26-035126.md) | [(85229.4%)](/filings/0001628280-26-057110.md) |
| Net margin | % | not reported | not reported | not reported | not reported | not reported | not reported | [(26381.3%)](/filings/0001628280-26-057110.md) | [(75000.0%)](/filings/0001628280-26-057110.md) |
| Diluted EPS | $ per share | [(6.31)](/filings/0001628280-25-052125.md) | not reported | [(1.41)](/filings/0001628280-26-035126.md) | [(0.56)](/filings/0001628280-26-057110.md) | [(0.69)](/filings/0001628280-25-052125.md) | not reported | [(0.14)](/filings/0001628280-26-035126.md) | [(0.41)](/filings/0001628280-26-057110.md) |
| Free cash flow | $m | [(7.9) d](/filings/0001628280-25-052125.md) | [(13.5) d](/filings/0001628280-26-021580.md) | [(14.1)](/filings/0001628280-26-035126.md) | [(13.3) d](/filings/0001628280-26-057110.md) | [(9.4) d](/filings/0001628280-25-052125.md) | [(6.9) d](/filings/0001628280-26-021580.md) | not reported | not reported |

- Revenue. XBRL Revenue: us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. Derived values: 12-month figure less the 9-month figure.
- Gross margin (gross profit / revenue). XBRL Revenue: us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. Derived values: 12-month figure less the 9-month figure.
- Operating margin (operating income / revenue). XBRL Operating income: us-gaap:OperatingIncomeLoss; Revenue: us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. Derived values: 12-month figure less the 9-month figure.
- Net margin (net income / revenue). XBRL Net income: us-gaap:NetIncomeLoss; Revenue: us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. Derived values: 12-month figure less the 9-month figure.
- Diluted EPS. XBRL Diluted EPS: us-gaap:EarningsPerShareDiluted.
- Free cash flow (operating cash flow − capital expenditure). XBRL Operating cash flow: us-gaap:NetCashProvidedByUsedInOperatingActivities; Capital expenditure: us-gaap:PaymentsToAcquirePropertyPlantAndEquipment. Derived values: 9-month figure less the 6-month figure; 12-month figure less the 9-month figure; 6-month figure less the 3-month figure.

## Last five fiscal years

| Line item | Unit | FY2021 (2021-12-31) | FY2022 (2022-12-31) | FY2023 (2023-12-31) | FY2024 (2024-12-31) | FY2025 (2025-12-31) |
| --- | --- | ---: | ---: | ---: | ---: | ---: |
| Revenue | $m | [2.3](/filings/0001854270-23-000033.md) | [3.3](/filings/0001854270-24-000029.md) | [2.0](/filings/0001854270-25-000042.md) | [0.0](/filings/0001628280-26-021580.md) | [0.0](/filings/0001628280-26-021580.md) |
| Gross margin | % | not reported | not reported | not reported | not reported | not reported |
| Operating margin | % | [(1765.4%)](/filings/0001854270-23-000033.md) | [(1889.3%)](/filings/0001854270-24-000029.md) | [(4687.9%)](/filings/0001854270-25-000042.md) | not reported | [(312631.8%)](/filings/0001628280-26-021580.md) |
| Net margin | % | [(2414.6%)](/filings/0001854270-23-000033.md) | [(1771.5%)](/filings/0001854270-24-000029.md) | [(3592.4%)](/filings/0001854270-25-000042.md) | not reported | [(279263.6%)](/filings/0001628280-26-021580.md) |
| Diluted EPS | $ per share | [(19.00)](/filings/0001854270-23-000033.md) | [(2.23)](/filings/0001854270-24-000029.md) | [(16.01)](/filings/0001854270-25-000042.md) | [(12.03)](/filings/0001628280-26-021580.md) | [(2.73)](/filings/0001628280-26-021580.md) |
| Free cash flow | $m | [(40.2)](/filings/0001854270-23-000033.md) | [(76.3)](/filings/0001854270-24-000029.md) | [(64.4)](/filings/0001854270-25-000042.md) | [(41.4)](/filings/0001628280-26-021580.md) | [(43.6)](/filings/0001628280-26-021580.md) |

- Revenue. XBRL Revenue: us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax.
- Gross margin (gross profit / revenue). XBRL Revenue: us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax.
- Operating margin (operating income / revenue). XBRL Operating income: us-gaap:OperatingIncomeLoss; Revenue: us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax.
- Net margin (net income / revenue). XBRL Net income: us-gaap:NetIncomeLoss; Revenue: us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax.
- Diluted EPS. XBRL Diluted EPS: us-gaap:EarningsPerShareDiluted.
- Free cash flow (operating cash flow − capital expenditure). XBRL Operating cash flow: us-gaap:NetCashProvidedByUsedInOperatingActivities; Capital expenditure: us-gaap:PaymentsToAcquirePropertyPlantAndEquipment.

Each value links to the filing it came from. d marks a derived value. A ratio is not reported when any input is missing.

## Insider purchases and sales

The last 20 open-market transactions on Form 4 (codes P and S). Reported price is as stated on the form, not a market price. [All insider transactions](/companies/snti/insiders.md)

None in coverage.

## Funds that report holding it

From each manager’s latest Form 13F, largest reported value first. Reported value is as filed: filing data, not a price. [All funds](/funds.md)

| Fund | Quarter ended | Reported value | Shares | Put or call | Change on the quarter before |
| --- | --- | ---: | ---: | --- | --- |
| [Nantahala Capital Management, LLC](/funds/1472322.md) | 2026-06-30 | $976.8k | 888,000 |  | New +888,000 |
| [VANGUARD CAPITAL MANAGEMENT LLC](/funds/2100119.md) | 2026-06-30 | $591.3k | 537,504 |  | New +537,504 |
| [GEODE CAPITAL MANAGEMENT, LLC](/funds/1214717.md) | 2026-06-30 | $205.8k | 187,065 |  | New +187,065 |
| [CITADEL ADVISORS LLC](/funds/1423053.md) | 2026-06-30 | $117.8k | 107,100 |  | New +107,100 |
| [VANGUARD FIDUCIARY TRUST CO](/funds/933478.md) | 2026-06-30 | $100.3k | 91,193 |  | New +91,193 |
| [JANE STREET GROUP, LLC](/funds/1595888.md) | 2026-06-30 | $57.8k | 52,530 |  | New +52,530 |
| [Menlo Ventures Management, L.P.](/funds/1911541.md) | 2026-06-30 | $39.3k | 35,737 |  | New +35,737 |
| [NORTHERN TRUST CORP](/funds/73124.md) | 2026-06-30 | $35.4k | 32,154 |  | New +32,154 |
| [XTX Topco Ltd](/funds/1828301.md) | 2026-06-30 | $26.0k | 23,610 |  | New +23,610 |
| [UBS Group AG](/funds/1610520.md) | 2026-06-30 | $15.9k | 14,432 |  | New +14,432 |

## Recent filings

[All 361 filings](/companies/snti/filings.md)

| Filed | Accepted | Form | What it is | Accession |
| --- | --- | --- | --- | --- |
| 2026-10-26 | 16:17 ET | [8-K](/filings/0001140361-26-040772.md) | 1.01 Entry into a material agreement; 1.02 Termination of a material agreement; 2.01 Completion of an acquisition or disposition; 3.02 Unregistered sale of equity; 9.01 Financial statements and exhibits | 0001140361-26-040772 |
| 2026-10-15 | 16:02 ET | [8-K](/filings/0001628280-26-065992.md) | 5.07 Shareholder vote results | 0001628280-26-065992 |
| 2026-10-13 | 16:01 ET | [8-K](/filings/0001628280-26-065685.md) | 8.01 Other events | 0001628280-26-065685 |
| 2026-09-24 | 16:03 ET | [8-K](/filings/0001628280-26-063369.md) | 5.02 Departure or appointment of officers or directors | 0001628280-26-063369 |
| 2026-09-11 | 17:00 ET | [SCHEDULE 13D/A](/filings/0000902664-26-003795.md) | Ownership report, active investor, amended | 0000902664-26-003795 |
| 2026-09-04 | 06:01 ET | [8-K](/filings/0001628280-26-060600.md) | 1.01 Entry into a material agreement; 2.03 New direct financial obligation; 9.01 Financial statements and exhibits | 0001628280-26-060600 |
| 2026-09-02 | 16:29 ET | [8-K](/filings/0001628280-26-060124.md) | 1.01 Entry into a material agreement; 3.01 Delisting notice | 0001628280-26-060124 |
| 2026-08-20 | 16:25 ET | [8-K](/filings/0001628280-26-058258.md) | 1.01 Entry into a material agreement; 2.03 New direct financial obligation | 0001628280-26-058258 |
| 2026-08-14 | 16:10 ET | [10-Q](/filings/0001628280-26-057110.md) | Quarterly report, period 2026-06-30 | 0001628280-26-057110 |
| 2026-07-16 | 13:56 ET | [SCHEDULE 13D/A](/filings/0000902664-26-003126.md) | Ownership report, active investor, amended | 0000902664-26-003126 |

## Latest annual report

[Form 10-K for the fiscal year ended Dec 31, 2025](/filings/0001628280-26-021580.md), filed Mar 27, 2026.

## Forecast league

Q3 FY2026, the quarter ended 2026-09-30, is open for forecasts until the first results filing for it is accepted by EDGAR. Results are due by \[object Promise\]. [Forecast this quarter](/leagues/2026q3/targets/824d003e-7c91-4ebf-a16b-4c3ff1014484)

## About the filer

- CIK: 1854270
- Tickers: SNTI
- Exchange: Nasdaq
- SIC code: 2836 Biological Products, (No Diagnostic Substances)
- State of incorporation: DE
- Filer category: <br>Emerging growth company

Source: SEC EDGAR, XBRL company facts, the filing index and Forms 4. Last ingested by Listed: Oct 27, 2026, 16:38 ET. No prices; not investment advice.
