# ARCH Venture Management, LLC: Form 13F holdings

An institutional investment manager in CHICAGO, IL. SEC CIK 1274403.

- Quarter ended: 2026-06-30
- Filed: 2026-08-14
- Reported value: $1.10bn
- Positions: 12 (12 lines in the filing's table; lines for the same security and option type are added together here)
- Compared with: the 13F for the quarter ended 2026-03-31
- Filing: https://www.sec.gov/Archives/edgar/data/1274403/000101297526000794/

## Holdings

As filed, largest first. Reported value is what the manager stated at the quarter end (Jun 30, 2026), in US dollars; it is filing data, not a price. Weight is the share of the total reported value.

| Issuer | Class | Reported value | Weight | Shares | Put or call | Change on the quarter before |
| --- | --- | ---: | ---: | ---: | --- | --- |
| [PARABILIS MEDICINES INC (PBLS)](/companies/pbls.md) | COM | $175.5m | 16.0% | 6,412,780 |  | New +6,412,780 |
| [BEAM THERAPEUTICS INC (BEAM)](/companies/beam.md) | COM | $155.8m | 14.2% | 4,540,132 |  | Unchanged |
| [RAPPORT THERAPEUTICS INC (RAPP)](/companies/rapp.md) | COM | $155.4m | 14.1% | 3,728,738 |  | Unchanged |
| [SEAPORT THERAPEUTICS INC (SPTX)](/companies/sptx.md) | COMMON STOCK | $136.6m | 12.4% | 6,294,951 |  | New +6,294,951 |
| [ERASCA INC (ERAS)](/companies/eras.md) | COM | $129.9m | 11.8% | 7,091,557 |  | Unchanged |
| [VIR BIOTECHNOLOGY INC (VIR)](/companies/vir.md) | COM | $129.4m | 11.8% | 12,694,163 |  | Reduced −222,500 |
| [MAZE THERAPEUTICS INC (MAZE)](/companies/maze.md) | COM | $123.0m | 11.2% | 4,120,053 |  | Unchanged |
| [LYELL IMMUNOPHARMA INC (LYEL)](/companies/lyel.md) | COM NEW | $45.5m | 4.1% | 3,247,162 |  | Unchanged |
| [GENERATE BIOMEDICINES INC (GENB)](/companies/genb.md) | COM SHS | $32.8m | 3.0% | 1,944,426 |  | Unchanged |
| [10X GENOMICS INC (TXG)](/companies/txg.md) | CL A COM | $8.4m | 0.8% | 217,834 |  | Unchanged |
| [BOUNDLESS BIO INC (BOLD)](/companies/bold.md) | COM | $6.7m | 0.6% | 2,694,095 |  | New +2,694,095 |
| GOSSAMER BIO INC | COM | $1.3m | 0.1% | 8,055,916 |  | Unchanged |

## Sold out

Held at the end of the quarter before and not reported this quarter.

| Issuer | Class | Reported value | Weight | Shares | Put or call | Change on the quarter before |
| --- | --- | ---: | ---: | ---: | --- | --- |
| [Q32 BIO INC (QTTB)](/companies/qttb.md) | COM | $0 | 0.0% | 0 |  | Sold out −320,482 |

Source: SEC EDGAR, Form 13F-HR, accession 0001012975-26-000794. Last ingested by Listed: Oct 22, 2026, 05:26 ET. No prices; not investment advice.