# Sio Capital Management, LLC: Form 13F holdings

An institutional investment manager in NEW YORK, NY. SEC CIK 1482416.

- Quarter ended: 2026-06-30
- Filed: 2026-08-14
- Reported value: $604.3m
- Positions: 59 (59 lines in the filing's table; lines for the same security and option type are added together here)
- Compared with: the 13F for the quarter ended 2026-03-31
- Filing: https://www.sec.gov/Archives/edgar/data/1482416/000121465926010311/

## Holdings

As filed, largest first. Reported value is what the manager stated at the quarter end (Jun 30, 2026), in US dollars; it is filing data, not a price. Weight is the share of the total reported value.

| Issuer | Class | Reported value | Weight | Shares | Put or call | Change on the quarter before |
| --- | --- | ---: | ---: | ---: | --- | --- |
| [ANTERIS TECHNOLOGIES GLOBAL (AVR)](/companies/avr.md) | COM | $54.6m | 9.0% | 5,545,984 |  | Added +163,019 |
| [CENCORA INC (COR)](/companies/cor.md) | COM | $49.1m | 8.1% | 173,588 |  | Added +72,694 |
| [MAXIMUS INC (MMS)](/companies/mms.md) | COM | $38.5m | 6.4% | 715,267 |  | Reduced −53,558 |
| [ALLOGENE THERAPEUTICS INC (ALLO)](/companies/allo.md) | COM | $27.7m | 4.6% | 13,323,431 |  | New +13,323,431 |
| [GLOBUS MED INC (GMED)](/companies/gmed.md) | CL A | $23.8m | 3.9% | 301,816 |  | New +301,816 |
| [GSK PLC (GSK)](/companies/gsk.md) | SPONSORED ADR | $22.9m | 3.8% | 436,700 |  | Added +50,821 |
| [TYRA BIOSCIENCES INC (TYRA)](/companies/tyra.md) | COM | $22.2m | 3.7% | 695,315 |  | Added +89,876 |
| [WAYSTAR HLDG CORP (WAY)](/companies/way.md) | COM | $19.0m | 3.1% | 925,834 |  | Reduced −716,402 |
| [SELLAS LIFE SCIENCES GROUP I (SLS)](/companies/sls.md) | COM NEW | $18.2m | 3.0% | 1,230,700 | Put | New +1,230,700 |
| [IDEAYA BIOSCIENCES INC (IDYA)](/companies/idya.md) | COM | $17.9m | 3.0% | 480,383 |  | New +480,383 |
| [ORUKA THERAPEUTICS INC (ORKA)](/companies/orka.md) | COM | $16.9m | 2.8% | 177,118 |  | Added +44,622 |
| [THE CIGNA GROUP (CI)](/companies/ci.md) | COM | $15.9m | 2.6% | 57,750 |  | New +57,750 |
| [SANOFI SA (SNY)](/companies/sny.md) | SPONSORED ADR | $15.5m | 2.6% | 364,200 |  | Added +124,529 |
| ICON PUB LTD CO | SHS | $15.3m | 2.5% | 88,186 |  | Reduced −218,172 |
| [VIATRIS INC (VTRS)](/companies/vtrs.md) | COM | $15.2m | 2.5% | 954,299 |  | New +954,299 |
| CROSS CTRY HEALTHCARE INC | COM | $14.5m | 2.4% | 1,098,393 |  | Unchanged |
| [RAPPORT THERAPEUTICS INC (RAPP)](/companies/rapp.md) | COM | $12.8m | 2.1% | 307,657 |  | Reduced −59,152 |
| [ABBOTT LABORATORIES (ABT)](/companies/abt.md) | COM | $11.7m | 1.9% | 128,656 |  | Reduced −57,918 |
| [CELCUITY INC (CELC)](/companies/celc.md) | COM | $11.5m | 1.9% | 110,022 |  | Reduced −83,821 |
| [ZIMMER BIOMET HOLDINGS INC (ZBH)](/companies/zbh.md) | COM | $11.3m | 1.9% | 131,445 |  | Added +68,832 |
| [REGENERON PHARMACEUTICALS (REGN)](/companies/regn.md) | COM | $11.2m | 1.9% | 18,000 |  | New +18,000 |
| [BRISTOL-MYERS SQUIBB CO (BMY)](/companies/bmy.md) | COM | $11.1m | 1.8% | 193,500 |  | New +193,500 |
| MEDTRONIC PLC | SHS | $11.1m | 1.8% | 142,500 |  | New +142,500 |
| [VIR BIOTECHNOLOGY INC (VIR)](/companies/vir.md) | COM | $11.0m | 1.8% | 1,075,274 |  | Reduced −423,346 |
| [SENSEONICS HLDGS INC (SENS)](/companies/sens.md) | COM | $9.0m | 1.5% | 1,592,692 |  | Added +1,476,908 |
| [EYEPOINT INC (EYPT)](/companies/eypt.md) | COM NEW | $8.9m | 1.5% | 623,130 |  | Reduced −98,655 |
| CYBIN INC | COM NEW | $8.6m | 1.4% | 1,300,000 |  | New +1,300,000 |
| [ANI PHARMACEUTICALS INC (ANIP)](/companies/anip.md) | COM | $8.1m | 1.3% | 97,305 |  | Reduced −168,238 |
| [PROTARA THERAPEUTICS INC (TARA)](/companies/tara.md) | COM STK | $7.3m | 1.2% | 1,921,872 |  | Reduced −47,967 |
| [RELMADA THERAPEUTICS INC (RLMD)](/companies/rlmd.md) | COM | $6.9m | 1.1% | 1,003,562 |  | Added +38,562 |
| [TANGO THERAPEUTICS INC (TNGX)](/companies/tngx.md) | COM | $6.5m | 1.1% | 208,500 |  | New +208,500 |
| [AQUESTIVE THERAPEUTICS INC (AQST)](/companies/aqst.md) | COM | $6.2m | 1.0% | 1,486,175 |  | Reduced −436,712 |
| [DIANTHUS THERAPEUTICS INC (DNTH)](/companies/dnth.md) | COM | $5.8m | 1.0% | 59,254 |  | Reduced −310,791 |
| [SIONNA THERAPEUTICS INC (SION)](/companies/sion.md) | COM | $5.6m | 0.9% | 127,808 |  | Reduced −166,532 |
| [OCULAR THERAPEUTIX INC (OCUL)](/companies/ocul.md) | COM | $5.3m | 0.9% | 539,493 |  | Reduced −429,104 |
| [ZENAS BIOPHARMA INC (ZBIO)](/companies/zbio.md) | COM | $5.3m | 0.9% | 208,557 |  | Reduced −123,173 |
| [BRIGHT MINDS BIOSCIENCES INC (DRUG)](/companies/drug.md) | COM NEW | $5.2m | 0.9% | 73,952 |  | Reduced −12,131 |
| [ONKURE THERAPEUTICS INC (OKUR)](/companies/okur.md) | COM CL A | $4.9m | 0.8% | 1,078,965 |  | Unchanged |
| [SAVARA INC (SVRA)](/companies/svra.md) | COM | $3.8m | 0.6% | 617,675 |  | Added +3,787 |
| [PMV PHARMACEUTICALS INC (PMVP)](/companies/pmvp.md) | COM | $3.5m | 0.6% | 2,634,137 |  | Reduced −442,443 |
| [AVEANNA HEALTHCARE HLDGS INC (AVAH)](/companies/avah.md) | COM | $3.2m | 0.5% | 369,036 |  | New +369,036 |
| [OVID THERAPEUTICS INC (OVID)](/companies/ovid.md) | COM | $2.7m | 0.4% | 1,005,334 |  | Reduced −247,047 |
| [IMMUNOME INC (IMNM)](/companies/imnm.md) | COM | $2.6m | 0.4% | 124,168 |  | Reduced −40,942 |
| [HIMS & HERS HEALTH INC (HIMS)](/companies/hims.md) | COM CL A | $2.6m | 0.4% | 75,000 | Call | New +75,000 |
| [AN2 THERAPEUTICS INC (ANTX)](/companies/antx.md) | COM | $2.6m | 0.4% | 529,933 |  | Reduced −127,267 |
| [SERINA THERAPEUTICS INC (SER)](/companies/ser.md) | COM SHS | $1.9m | 0.3% | 1,000,000 |  | Unchanged |
| [ALIGOS THERAPEUTICS INC (ALGS)](/companies/algs.md) | COM NEW | $1.9m | 0.3% | 327,237 |  | Unchanged |
| [IBIO INC (IBIO)](/companies/ibio.md) | COM NEW | $1.6m | 0.3% | 904,268 |  | Unchanged |
| [XILIO THERAPEUTICS INC (XLO)](/companies/xlo.md) | COM | $1.5m | 0.2% | 152,464 |  | Unchanged |
| [ARTIVION INC (AORT)](/companies/aort.md) | COM | $1.1m | 0.2% | 48,481 |  | New +48,481 |
| [BRIDGEBIO ONCOLOGY THERAPEUT (BBOT)](/companies/bbot.md) | COM NEW | $995.4k | 0.2% | 130,628 |  | Unchanged |
| [TELA BIO INC (TELA)](/companies/tela.md) | COM | $477.2k | <0.1% | 636,300 |  | Unchanged |
| [ADAGIO MED HLDGS INC (ADGM)](/companies/adgm.md) | COM | $455.5k | <0.1% | 698,989 |  | Reduced −589,472 |
| [NEUROONE MED TECHNOLOGIES CO (NMTC)](/companies/nmtc.md) | COM | $251.6k | <0.1% | 82,767 |  | New +82,767 |
| [ENVERIC BIOSCIENCES INC (ENVB)](/companies/envb.md) | COM SHS | $248.4k | <0.1% | 180,000 |  | New +180,000 |
| [MODULAR MED INC (MODD)](/companies/modd.md) | COM NEW | $117.9k | <0.1% | 26,190 |  | Unchanged |
| [QT IMAGING HLDGS INC (QTI)](/companies/qti.md) | COM | $62.0k | <0.1% | 15,236 |  | New +15,236 |
| ROCKET PHARMACEUTICALS INC | \*W EXP 09/02/202 | $1.5k | <0.1% | 400,000 |  | Unchanged |
| HUMACYTE INC | \*W EXP 08/27/202 | $477 | <0.1% | 49,998 |  | Unchanged |

## Sold out

Held at the end of the quarter before and not reported this quarter.

| Issuer | Class | Reported value | Weight | Shares | Put or call | Change on the quarter before |
| --- | --- | ---: | ---: | ---: | --- | --- |
| [ABIVAX SA (ABVX)](/companies/abvx.md) | SPONSORED ADS | $0 | 0.0% | 0 |  | Sold out −135,800 |
| BIOHAVEN LTD | COM | $0 | 0.0% | 0 |  | Sold out −1,163,926 |
| [BIOMARIN PHARMACEUTICAL INC (BMRN)](/companies/bmrn.md) | COM | $0 | 0.0% | 0 |  | Sold out −194,226 |
| [BOUNDLESS BIO INC (BOLD)](/companies/bold.md) | COM | $0 | 0.0% | 0 |  | Sold out −163,679 |
| [CENTENE CORP DEL (CNC)](/companies/cnc.md) | COM | $0 | 0.0% | 0 | Put | Sold out −100,000 |
| [COMPASS PATHWAYS PLC (CMPS)](/companies/cmps.md) | SPONSORED ADS | $0 | 0.0% | 0 |  | Sold out −1,506,525 |
| [CONTEXT THERAPEUTICS INC (CNTX)](/companies/cntx.md) | COM | $0 | 0.0% | 0 |  | Sold out −917,922 |
| [CORCEPT THERAPEUTICS INC (CORT)](/companies/cort.md) | COM | $0 | 0.0% | 0 |  | Sold out −674,759 |
| CRINETICS PHARMACEUTICALS IN | COM | $0 | 0.0% | 0 |  | Sold out −249,887 |
| [DISC MEDICINE INC (IRON)](/companies/iron.md) | COM | $0 | 0.0% | 0 |  | Sold out −65,203 |
| [EDGEWISE THERAPEUTICS INC (EWTX)](/companies/ewtx.md) | COM | $0 | 0.0% | 0 |  | Sold out −268,986 |
| [ELICIO THERAPEUTICS INC (ELTX)](/companies/eltx.md) | COM | $0 | 0.0% | 0 | Put | Sold out −11,700 |
| [EMBECTA CORP (EMBC)](/companies/embc.md) | COMMON STOCK | $0 | 0.0% | 0 |  | Sold out −1,847,850 |
| [ENANTA PHARMACEUTICALS INC (ENTA)](/companies/enta.md) | COM | $0 | 0.0% | 0 |  | Sold out −40,000 |
| [ERASCA INC (ERAS)](/companies/eras.md) | COM | $0 | 0.0% | 0 |  | Sold out −5,000 |
| [FOGHORN THERAPEUTICS INC (FHTX)](/companies/fhtx.md) | COM | $0 | 0.0% | 0 |  | Sold out −122,889 |
| [HAEMONETICS CORP MASS (HAE)](/companies/hae.md) | COM | $0 | 0.0% | 0 |  | Sold out −220,672 |
| [HYPERFINE INC (HYPR)](/companies/hypr.md) | COM CL A | $0 | 0.0% | 0 |  | Sold out −1,000,000 |
| [INTEGRA LIFESCIENCES HLDGS C (IART)](/companies/iart.md) | COM NEW | $0 | 0.0% | 0 |  | Sold out −383,140 |
| [KYMERA THERAPEUTICS INC (KYMR)](/companies/kymr.md) | COM | $0 | 0.0% | 0 |  | Sold out −32,235 |
| LIVANOVA PLC | SHS | $0 | 0.0% | 0 |  | Sold out −421,615 |
| [MONOPAR THERAPEUTICS INC (MNPR)](/companies/mnpr.md) | COM NEW | $0 | 0.0% | 0 |  | Sold out −173,506 |
| NEUROONE MED TECHNOLOGIES CO | COM NEW | $0 | 0.0% | 0 |  | Sold out −496,614 |
| NYXOAH S A | SHS | $0 | 0.0% | 0 |  | Sold out −50,839 |
| [ORGANON & CO (OGN)](/companies/ogn.md) | COMMON STOCK | $0 | 0.0% | 0 |  | Sold out −865,908 |
| [OSCAR HEALTH INC (OSCR)](/companies/oscr.md) | CL A | $0 | 0.0% | 0 | Put | Sold out −3,000 |
| PROQR THERAPEUTICS N V | SHS EURO | $0 | 0.0% | 0 |  | Sold out −1,954,715 |
| [QUIDELORTHO CORP (QDEL)](/companies/qdel.md) | COM | $0 | 0.0% | 0 |  | Sold out −359,011 |
| [REPLIMUNE GROUP INC (REPL)](/companies/repl.md) | COM | $0 | 0.0% | 0 |  | Sold out −720,036 |
| [SHOULDER INNOVATIONS INC (SI)](/companies/si.md) | COMMON STOCK | $0 | 0.0% | 0 |  | Sold out −210,641 |
| SIMULATIONS PLUS INC | COM | $0 | 0.0% | 0 |  | Sold out −200 |
| [STRUCTURE THERAPEUTICS INC (GPCR)](/companies/gpcr.md) | SPONSORED ADS | $0 | 0.0% | 0 |  | Sold out −209,093 |
| [TELEFLEX INCORPORATED (TFX)](/companies/tfx.md) | COM | $0 | 0.0% | 0 |  | Sold out −94,800 |
| TERNS PHARMACEUTICALS INC | COM | $0 | 0.0% | 0 |  | Sold out −10,100 |

Source: SEC EDGAR, Form 13F-HR, accession 0001214659-26-010311. Last ingested by Listed: Oct 22, 2026, 05:26 ET. No prices; not investment advice.