# Casdin Capital, LLC: Form 13F holdings

An institutional investment manager in New York, NY. SEC CIK 1534261.

- Quarter ended: 2026-06-30
- Filed: 2026-08-14
- Reported value: $2.00bn
- Positions: 43 (43 lines in the filing's table; lines for the same security and option type are added together here)
- Compared with: the 13F for the quarter ended 2026-03-31
- Filing: https://www.sec.gov/Archives/edgar/data/1534261/000091957426005491/

## Holdings

As filed, largest first. Reported value is what the manager stated at the quarter end (Jun 30, 2026), in US dollars; it is filing data, not a price. Weight is the share of the total reported value.

| Issuer | Class | Reported value | Weight | Shares | Put or call | Change on the quarter before |
| --- | --- | ---: | ---: | ---: | --- | --- |
| [REVOLUTION MEDICINES INC (RVMD)](/companies/rvmd.md) | COM | $482.7m | 24.2% | 2,577,333 |  | Unchanged |
| [RELAY THERAPEUTICS INC (RLAY)](/companies/rlay.md) | COM | $300.0m | 15.0% | 16,035,240 |  | Added +1,616,666 |
| [GENEDX HOLDINGS CORP (WGS)](/companies/wgs.md) | COM CL A | $254.5m | 12.7% | 3,707,164 |  | Added +700,000 |
| BIOLIFE SOLUTIONS INC | COM NEW | $131.5m | 6.6% | 4,655,000 |  | Reduced −1,302,165 |
| [ILLUMINA INC (ILMN)](/companies/ilmn.md) | COM | $93.2m | 4.7% | 530,000 |  | Unchanged |
| [STANDARD BIOTOOLS INC (LAB)](/companies/lab.md) | COM | $73.0m | 3.7% | 88,783,856 |  | Unchanged |
| [STRUCTURE THERAPEUTICS INC (GPCR)](/companies/gpcr.md) | SPONSORED ADS | $63.1m | 3.2% | 1,175,000 |  | Unchanged |
| [DENALI THERAPEUTICS INC (DNLI)](/companies/dnli.md) | COM | $52.6m | 2.6% | 2,045,000 |  | Added +205,000 |
| [NEUROGENE INC (NGNE)](/companies/ngne.md) | COM | $48.6m | 2.4% | 1,545,361 |  | Added +125,000 |
| [BEAM THERAPEUTICS INC (BEAM)](/companies/beam.md) | COM | $46.3m | 2.3% | 1,350,000 |  | Unchanged |
| [10X GENOMICS INC (TXG)](/companies/txg.md) | CL A COM | $40.3m | 2.0% | 1,050,000 |  | Reduced −1,225,000 |
| [SCHOLAR ROCK HLDG CORP (SRRK)](/companies/srrk.md) | COM | $36.6m | 1.8% | 665,000 |  | Added +315,000 |
| [PERSONALIS INC (PSNL)](/companies/psnl.md) | COM | $34.2m | 1.7% | 2,550,000 |  | Added +950,000 |
| [GRAIL INC (GRAL)](/companies/gral.md) | COM | $32.8m | 1.6% | 480,000 |  | Added +250,000 |
| [GUARDANT HEALTH INC (GH)](/companies/gh.md) | COM | $27.8m | 1.4% | 185,000 |  | Reduced −130,000 |
| [MAZE THERAPEUTICS INC (MAZE)](/companies/maze.md) | COM | $25.2m | 1.3% | 843,857 |  | Added +85,000 |
| [HIMS & HERS HEALTH INC (HIMS)](/companies/hims.md) | COM CL A | $24.3m | 1.2% | 700,000 |  | Unchanged |
| [ALNYLAM PHARMACEUTICALS INC (ALNY)](/companies/alny.md) | COM | $22.6m | 1.1% | 75,000 |  | Unchanged |
| [TAYSHA GENE THERAPIES INC (TSHA)](/companies/tsha.md) | COM SHS | $22.1m | 1.1% | 3,250,000 |  | Unchanged |
| [AGOMAB THERAPEUTICS NV (AGMB)](/companies/agmb.md) | SPONSORED ADS | $20.1m | 1.0% | 1,550,000 |  | Unchanged |
| [SEPTERNA INC (SEPN)](/companies/sepn.md) | COM | $18.5m | 0.9% | 553,268 |  | Unchanged |
| [PARABILIS MEDICINES INC (PBLS)](/companies/pbls.md) | COM | $17.7m | 0.9% | 645,690 |  | New +645,690 |
| [SIONNA THERAPEUTICS INC (SION)](/companies/sion.md) | COM | $17.6m | 0.9% | 400,000 |  | New +400,000 |
| [VERACYTE INC (VCYT)](/companies/vcyt.md) | COM | $16.2m | 0.8% | 276,308 |  | Unchanged |
| [ADLAI NORTYE LTD (ANL)](/companies/anl.md) | SPONSORED ADS | $14.4m | 0.7% | 1,250,000 |  | Added +711,539 |
| [PRIME MEDICINE INC (PRME)](/companies/prme.md) | COM | $11.7m | 0.6% | 3,167,175 |  | Unchanged |
| [ABSCI CORPORATION (ABSI)](/companies/absi.md) | COM | $11.3m | 0.6% | 973,260 |  | Unchanged |
| [QUEST DIAGNOSTICS INC (DGX)](/companies/dgx.md) | COM | $10.6m | 0.5% | 50,000 |  | Unchanged |
| [SAREPTA THERAPEUTICS INC (SRPT)](/companies/srpt.md) | COM | $8.4m | 0.4% | 470,000 |  | New +470,000 |
| UNIQURE NV | SHS | $6.9m | 0.3% | 150,000 |  | New +150,000 |
| [INTELLIA THERAPEUTICS INC (NTLA)](/companies/ntla.md) | COM | $6.0m | 0.3% | 355,000 |  | Unchanged |
| [MODERNA INC (MRNA)](/companies/mrna.md) | COM | $5.3m | 0.3% | 75,000 |  | Unchanged |
| [DISC MEDICINE INC (IRON)](/companies/iron.md) | COM | $4.8m | 0.2% | 65,000 |  | Unchanged |
| [MONTE ROSA THERAPEUTICS INC (GLUE)](/companies/glue.md) | COM | $4.5m | 0.2% | 186,014 |  | Unchanged |
| [CENTURY THERAPEUTICS INC (IPSC)](/companies/ipsc.md) | COM | $3.0m | 0.2% | 1,228,190 |  | Unchanged |
| [CONTINEUM THERAPEUTICS INC (CTNM)](/companies/ctnm.md) | CL A | $2.4m | 0.1% | 148,333 |  | Unchanged |
| [BRIDGEBIO ONCOLOGY THERAPEUT (BBOT)](/companies/bbot.md) | COM NEW | $2.2m | 0.1% | 282,312 |  | Unchanged |
| [EDITAS MEDICINE INC (EDIT)](/companies/edit.md) | COM | $1.4m | <0.1% | 445,000 |  | New +445,000 |
| [PACIFIC BIOSCIENCES CALIF IN (PACB)](/companies/pacb.md) | COM | $1.2m | <0.1% | 723,767 |  | Unchanged |
| [KARDIGAN INC (KARD)](/companies/kard.md) | COM | $1.2m | <0.1% | 50,000 |  | New +50,000 |
| [RECURSION PHARMACEUTICALS IN (RXRX)](/companies/rxrx.md) | CL A | $606.7k | <0.1% | 165,323 |  | Unchanged |
| [GINKGO BIOWORKS HOLDINGS INC (DNA)](/companies/dna.md) | CL A NEW | $361.6k | <0.1% | 36,493 |  | Unchanged |
| [TENAYA THERAPEUTICS INC (TNYA)](/companies/tnya.md) | COM | $267.5k | <0.1% | 361,969 |  | Unchanged |

## Sold out

Held at the end of the quarter before and not reported this quarter.

| Issuer | Class | Reported value | Weight | Shares | Put or call | Change on the quarter before |
| --- | --- | ---: | ---: | ---: | --- | --- |
| [MOONLAKE IMMUNOTHERAPEUTICS (MLTX)](/companies/mltx.md) | CLASS A ORD | $0 | 0.0% | 0 |  | Sold out −450,000 |
| QIAGEN NV | ORD SHARES | $0 | 0.0% | 0 |  | Sold out −360,000 |
| [TEMPUS AI INC (TEM)](/companies/tem.md) | CL A | $0 | 0.0% | 0 |  | Sold out −294,127 |

Source: SEC EDGAR, Form 13F-HR, accession 0000919574-26-005491. Last ingested by Listed: Oct 22, 2026, 05:26 ET. No prices; not investment advice.