# SILVERARC CAPITAL MANAGEMENT, LLC: Form 13F holdings

An institutional investment manager in BOSTON, MA. SEC CIK 1816307.

- Quarter ended: 2026-06-30
- Filed: 2026-08-13
- Reported value: $962.2m
- Positions: 73 (73 lines in the filing's table; lines for the same security and option type are added together here)
- Compared with: the 13F for the quarter ended 2026-03-31
- Filing: https://www.sec.gov/Archives/edgar/data/1816307/000142050626001563/

## Holdings

As filed, largest first. Reported value is what the manager stated at the quarter end (Jun 30, 2026), in US dollars; it is filing data, not a price. Weight is the share of the total reported value.

| Issuer | Class | Reported value | Weight | Shares | Put or call | Change on the quarter before |
| --- | --- | ---: | ---: | ---: | --- | --- |
| ASCENDIS PHARMA A/S | ORD SHS | $55.0m | 5.7% | 206,234 |  | New +206,234 |
| [CELCUITY INC (CELC)](/companies/celc.md) | COM | $52.4m | 5.4% | 500,996 |  | Added +143,093 |
| [COGENT BIOSCIENCES INC (COGT)](/companies/cogt.md) | COM | $49.6m | 5.2% | 1,280,707 |  | Reduced −33,482 |
| UROGEN PHARMA LTD | COM | $47.9m | 5.0% | 1,301,979 |  | Reduced −201,066 |
| [IMMUNOME INC (IMNM)](/companies/imnm.md) | COM | $42.7m | 4.4% | 2,017,009 |  | Added +166,731 |
| [DIANTHUS THERAPEUTICS INC (DNTH)](/companies/dnth.md) | COM | $38.0m | 4.0% | 390,000 |  | Reduced −264,746 |
| [RHYTHM PHARMACEUTICALS INC (RYTM)](/companies/rytm.md) | COM | $34.6m | 3.6% | 311,461 |  | Added +5,461 |
| [ORUKA THERAPEUTICS INC (ORKA)](/companies/orka.md) | COM | $33.6m | 3.5% | 352,802 |  | Added +201,894 |
| [MONTE ROSA THERAPEUTICS INC (GLUE)](/companies/glue.md) | COM | $26.8m | 2.8% | 1,108,295 |  | Reduced −893,745 |
| [SYNDAX PHARMACEUTICALS INC (SNDX)](/companies/sndx.md) | COM | $26.5m | 2.8% | 1,214,390 |  | Added +325,403 |
| [ENLIVEN THERAPEUTICS INC (ELVN)](/companies/elvn.md) | COM | $24.8m | 2.6% | 489,382 |  | New +489,382 |
| [IMMUNOVANT INC (IMVT)](/companies/imvt.md) | COM | $23.9m | 2.5% | 619,096 |  | Added +204,860 |
| [ERASCA INC (ERAS)](/companies/eras.md) | COM | $23.1m | 2.4% | 1,263,026 |  | Reduced −588,786 |
| [SAGIMET BIOSCIENCES INC (SGMT)](/companies/sgmt.md) | COM SER A | $22.6m | 2.4% | 2,927,698 |  | New +2,927,698 |
| [ABIVAX SA (ABVX)](/companies/abvx.md) | SPONSORED ADS | $22.6m | 2.3% | 169,593 |  | Reduced −132,937 |
| [PRAXIS PRECISION MEDICINES I (PRAX)](/companies/prax.md) | COM NEW | $22.0m | 2.3% | 65,679 |  | Reduced −5,873 |
| [KODIAK SCIENCES INC (KOD)](/companies/kod.md) | COM | $21.3m | 2.2% | 546,256 |  | Reduced −445,674 |
| ARK ETF TR | PUT | $21.0m | 2.2% | 500,000 | Put | New +500,000 |
| [DEFINIUM THERAPEUTICS INC (DFTX)](/companies/dftx.md) | COM SHS | $18.8m | 2.0% | 400,000 |  | New +400,000 |
| [VERACYTE INC (VCYT)](/companies/vcyt.md) | COM | $18.7m | 1.9% | 318,001 |  | Added +138,301 |
| SYNDAX PHARMACEUTICALS INC | CALL | $15.2m | 1.6% | 693,600 | Call | Added +373,600 |
| [GUARDANT HEALTH INC (GH)](/companies/gh.md) | COM | $15.0m | 1.6% | 99,826 |  | Added +1,312 |
| [C4 THERAPEUTICS INC (CCCC)](/companies/cccc.md) | COM STK | $14.2m | 1.5% | 3,032,060 |  | Added +1,120,275 |
| [ZENAS BIOPHARMA INC (ZBIO)](/companies/zbio.md) | COM | $12.9m | 1.3% | 509,789 |  | Reduced −626,146 |
| [TREVI THERAPEUTICS INC (TRVI)](/companies/trvi.md) | COM | $12.6m | 1.3% | 678,095 |  | Added +166,968 |
| HELIX ACQUISITION CORP III | USD CL A ORD SHS | $12.5m | 1.3% | 1,177,821 |  | Reduced −31,165 |
| [ALX ONCOLOGY HLDGS INC (ALXO)](/companies/alxo.md) | COM | $11.9m | 1.2% | 5,744,757 |  | New +5,744,757 |
| [VERADERMICS INC (MANE)](/companies/mane.md) | COMMON STOCK | $11.7m | 1.2% | 95,000 |  | New +95,000 |
| [XENON PHARMACEUTICALS INC (XENE)](/companies/xene.md) | COM | $11.3m | 1.2% | 186,821 |  | Reduced −10,938 |
| [AVALYN PHARMACEUTICALS INC (AVLN)](/companies/avln.md) | COM SHS | $10.9m | 1.1% | 330,487 |  | New +330,487 |
| [BIOGEN INC (BIIB)](/companies/biib.md) | COM | $10.4m | 1.1% | 48,101 |  | Reduced −2,866 |
| [ACLARIS THERAPEUTICS INC (ACRS)](/companies/acrs.md) | COM | $10.3m | 1.1% | 1,946,482 |  | New +1,946,482 |
| [CERUS CORP (CERS)](/companies/cers.md) | COM | $10.1m | 1.1% | 3,472,737 |  | Added +296,190 |
| [AVALO THERAPEUTICS INC (AVTX)](/companies/avtx.md) | COM NEW | $9.2m | 1.0% | 500,402 |  | New +500,402 |
| [BENITEC BIOPHARMA INC (BNTC)](/companies/bntc.md) | COM NEW | $9.1m | 0.9% | 679,826 |  | Reduced −37,899 |
| [VAXCYTE INC (PCVX)](/companies/pcvx.md) | COM | $8.4m | 0.9% | 145,000 |  | Added +19 |
| [GENEDX HOLDINGS CORP (WGS)](/companies/wgs.md) | COM CL A | $8.4m | 0.9% | 122,269 |  | New +122,269 |
| [SAVARA INC (SVRA)](/companies/svra.md) | COM | $8.3m | 0.9% | 1,355,459 |  | Reduced −75,523 |
| [OVID THERAPEUTICS INC (OVID)](/companies/ovid.md) | COM | $8.3m | 0.9% | 3,101,129 |  | Added +2,101,129 |
| [ORIC PHARMACEUTICALS INC (ORIC)](/companies/oric.md) | COM | $8.0m | 0.8% | 738,873 |  | Reduced −361,137 |
| ORIC PHARMACEUTICALS INC | CALL | $7.4m | 0.8% | 682,600 | Call | New +682,600 |
| MONTE ROSA THERAPEUTICS INC | CALL | $7.3m | 0.8% | 300,000 | Call | New +300,000 |
| [COMPASS PATHWAYS PLC (CMPS)](/companies/cmps.md) | SPONSORED ADS | $7.1m | 0.7% | 503,382 |  | Added +203,382 |
| COMPUGEN LTD | ORD | $6.8m | 0.7% | 3,184,257 |  | Reduced −131,588 |
| [SOLID BIOSCIENCES INC (SLDB)](/companies/sldb.md) | COM NEW | $6.7m | 0.7% | 668,450 |  | New +668,450 |
| ABIVAX SA | CALL | $6.7m | 0.7% | 50,000 | Call | New +50,000 |
| [IBIO INC (IBIO)](/companies/ibio.md) | COM NEW | $6.2m | 0.6% | 3,520,490 |  | Added +3,294,490 |
| [DISC MEDICINE INC (IRON)](/companies/iron.md) | COM | $6.1m | 0.6% | 82,800 |  | Reduced −113,228 |
| ALKERMES PLC | SHS | $5.9m | 0.6% | 113,494 |  | Reduced −346,820 |
| [SPYRE THERAPEUTICS INC (SYRE)](/companies/syre.md) | COM NEW | $5.3m | 0.6% | 59,959 |  | Reduced −126,659 |
| [ARTIVA BIOTHERAPEUTICS INC (ARTV)](/companies/artv.md) | COM | $5.1m | 0.5% | 525,000 |  | New +525,000 |
| [CONTINEUM THERAPEUTICS INC (CTNM)](/companies/ctnm.md) | CL A | $4.9m | 0.5% | 296,135 |  | Reduced −5,594 |
| UNIQURE NV | SHS | $4.8m | 0.5% | 105,000 |  | New +105,000 |
| RESEARCH ALLIANCE CORP III | ORD SHS CL A | $3.9m | 0.4% | 360,000 |  | New +360,000 |
| [ABEONA THERAPEUTICS INC (ABEO)](/companies/abeo.md) | COM NEW | $3.8m | 0.4% | 610,407 |  | Reduced −38,535 |
| [INSMED INC (INSM)](/companies/insm.md) | COM PAR $.01 | $3.7m | 0.4% | 34,438 |  | Reduced −1,412 |
| [KARYOPHARM THERAPEUTICS INC (KPTI)](/companies/kpti.md) | COM NEW | $2.9m | 0.3% | 297,460 |  | New +297,460 |
| KYMERA THERAPEUTICS INC | PUT | $2.9m | 0.3% | 25,000 | Put | New +25,000 |
| [CAMP4 THERAPEUTICS CORP (CAMP)](/companies/camp.md) | COM | $2.9m | 0.3% | 653,594 |  | Unchanged |
| [ELUTIA INC (ELUT)](/companies/elut.md) | CL A COM | $2.1m | 0.2% | 2,192,980 |  | Reduced −305,040 |
| [REVOLUTION MEDICINES INC (RVMD)](/companies/rvmd.md) | COM | $1.9m | 0.2% | 10,000 |  | New +10,000 |
| [SIONNA THERAPEUTICS INC (SION)](/companies/sion.md) | COM | $1.9m | 0.2% | 42,478 |  | Added +3,061 |
| ABSCI CORPORATION | PUT | $1.8m | 0.2% | 157,600 | Put | New +157,600 |
| [TELA BIO INC (TELA)](/companies/tela.md) | COM | $1.6m | 0.2% | 2,137,201 |  | Reduced −122,111 |
| [ACHIEVE LIFE SCIENCE INC (ACHV)](/companies/achv.md) | COM | $1.5m | 0.2% | 227,178 |  | New +227,178 |
| FULCRUM THERAPEUTICS INC | CALL | $1.4m | 0.1% | 391,900 | Call | Unchanged |
| FRACTYL HEALTH INC | COM | $1.3m | 0.1% | 1,637,976 |  | Reduced −63,649 |
| CONNECT BIOPHARMA HLDGS LTD | SHS | $1.3m | 0.1% | 545,000 |  | New +545,000 |
| CRESCENT BIOPHARMA INC. | COM | $1.1m | 0.1% | 59,104 |  | Reduced −71,396 |
| [CELLECTAR BIOSCIENCES INC (CLRB)](/companies/clrb.md) | COM NEW | $894.4k | <0.1% | 321,728 |  | New +321,728 |
| [FOGHORN THERAPEUTICS INC (FHTX)](/companies/fhtx.md) | COM | $224.4k | <0.1% | 45,975 |  | New +45,975 |
| [ADAGIO MED HLDGS INC (ADGM)](/companies/adgm.md) | COM | $146.2k | <0.1% | 224,360 |  | Reduced −27,612 |
| ROCKET PHARMACEUTICALS INC | \*W EXP 09/02/202 | $356 | <0.1% | 104,828 |  | Unchanged |

## Sold out

Held at the end of the quarter before and not reported this quarter.

| Issuer | Class | Reported value | Weight | Shares | Put or call | Change on the quarter before |
| --- | --- | ---: | ---: | ---: | --- | --- |
| [AARDVARK THERAPEUTICS INC (AARD)](/companies/aard.md) | COM | $0 | 0.0% | 0 |  | Sold out −33,684 |
| [ANNEXON INC (ANNX)](/companies/annx.md) | COM | $0 | 0.0% | 0 |  | Sold out −496,461 |
| ASCENDIS PHARMA A/S | SPONSORED ADR | $0 | 0.0% | 0 |  | Sold out −124,658 |
| CELCUITY INC | CALL | $0 | 0.0% | 0 | Call | Sold out −54,500 |
| [CELLDEX THERAPEUTICS INC NEW (CLDX)](/companies/cldx.md) | COM NEW | $0 | 0.0% | 0 |  | Sold out −178,378 |
| CENTESSA PHARMACEUTICALS PLC | SPONSORED ADS | $0 | 0.0% | 0 |  | Sold out −466,345 |
| [CG ONCOLOGY INC (CGON)](/companies/cgon.md) | COM | $0 | 0.0% | 0 |  | Sold out −166,349 |
| [CLIMB BIO INC (CLYM)](/companies/clym.md) | COM | $0 | 0.0% | 0 |  | Sold out −684,908 |
| COMPASS THERAPEUTICS INC | CALL | $0 | 0.0% | 0 | Call | Sold out −172,400 |
| [COMPASS THERAPEUTICS INC (CMPX)](/companies/cmpx.md) | COM | $0 | 0.0% | 0 |  | Sold out −859,049 |
| [CYTOKINETICS INC (CYTK)](/companies/cytk.md) | COM NEW | $0 | 0.0% | 0 |  | Sold out −71,203 |
| [EDGEWISE THERAPEUTICS INC (EWTX)](/companies/ewtx.md) | COM | $0 | 0.0% | 0 |  | Sold out −42,615 |
| [FULCRUM THERAPEUTICS INC (FULC)](/companies/fulc.md) | COM | $0 | 0.0% | 0 |  | Sold out −419,949 |
| [GENERATE BIOMEDICINES INC (GENB)](/companies/genb.md) | COM SHS | $0 | 0.0% | 0 |  | Sold out −100,000 |
| KALVISTA PHARMACEUTICALS INC | COM | $0 | 0.0% | 0 |  | Sold out −2,876,407 |
| [MONOPAR THERAPEUTICS INC (MNPR)](/companies/mnpr.md) | COM NEW | $0 | 0.0% | 0 |  | Sold out −43,488 |
| [NEUMORA THERAPEUTICS INC. (NMRA)](/companies/nmra.md) | COM | $0 | 0.0% | 0 |  | Sold out −818,156 |
| [NEXTCURE INC (NXTC)](/companies/nxtc.md) | COM NEW | $0 | 0.0% | 0 |  | Sold out −176,057 |
| NUVALENT INC | COM | $0 | 0.0% | 0 |  | Sold out −354,914 |
| [RADIOPHARM THERANOSTICS LTD (RADX)](/companies/radx.md) | SPONSORED ADS | $0 | 0.0% | 0 |  | Sold out −187,406 |
| [REPLIMUNE GROUP INC (REPL)](/companies/repl.md) | COM | $0 | 0.0% | 0 |  | Sold out −171,936 |
| [SCHOLAR ROCK HLDG CORP (SRRK)](/companies/srrk.md) | COM | $0 | 0.0% | 0 |  | Sold out −339,613 |
| SPDR SERIES TRUST | PUT | $0 | 0.0% | 0 | Put | Sold out −825,000 |
| [SURROZEN INC (SRZN)](/companies/srzn.md) | COM NEW | $0 | 0.0% | 0 |  | Sold out −144,255 |
| UNIQURE NV | CALL | $0 | 0.0% | 0 | Call | Sold out −500,000 |
| ZURA BIO LTD | CLASS A ORD SHS | $0 | 0.0% | 0 |  | Sold out −560,651 |

Source: SEC EDGAR, Form 13F-HR, accession 0001420506-26-001563. Last ingested by Listed: Oct 22, 2026, 05:26 ET. No prices; not investment advice.