# TRV GP VI, LLC: Form 13F holdings

An institutional investment manager in Boston, MA. SEC CIK 1990716.

- Quarter ended: 2026-06-30
- Filed: 2026-08-10
- Reported value: $232.3m
- Positions: 4 (4 lines in the filing's table; lines for the same security and option type are added together here)
- Compared with: the 13F for the quarter ended 2026-03-31
- Filing: https://www.sec.gov/Archives/edgar/data/1990716/000119312526340715/

## Holdings

As filed, largest first. Reported value is what the manager stated at the quarter end (Jun 30, 2026), in US dollars; it is filing data, not a price. Weight is the share of the total reported value.

| Issuer | Class | Reported value | Weight | Shares | Put or call | Change on the quarter before |
| --- | --- | ---: | ---: | ---: | --- | --- |
| [SEPTERNA, INC. (SEPN)](/companies/sepn.md) | COM | $141.0m | 60.7% | 4,211,659 |  | Unchanged |
| [SEAPORT THEREAPEUTICS, INC. (SPTX)](/companies/sptx.md) | COM | $44.8m | 19.3% | 2,061,222 |  | New +2,061,222 |
| [RAPPORT THERAPEUTICS, INC. (RAPP)](/companies/rapp.md) | COM | $40.4m | 17.4% | 969,218 |  | Unchanged |
| [TANGO THERAPEUTICS, INC. (TNGX)](/companies/tngx.md) | COM | $6.1m | 2.6% | 194,174 |  | Unchanged |

Source: SEC EDGAR, Form 13F-HR, accession 0001193125-26-340715. Last ingested by Listed: Oct 22, 2026, 05:26 ET. No prices; not investment advice.