Stonepine Capital Management, LLC
An institutional investment manager in Bend, OR. Its Form 13F for the quarter ended Jun 30, 2026, filed Aug 17, 2026. SEC CIK 1440771.
- Reported value$177.3m
- Positions87
Holdings: 87 positions
The filing on sec.govAs filed, largest first. Reported value is what the manager stated for each position at the quarter end, in US dollars; it is filing data, not a price. Weight is the position's share of the total reported value. Changes compare with the 13F for the quarter ended 2026-03-31.
| Issuer | Class | CUSIP | Reported value$m | Weight | Shares | Put or call | Change on the quarter before |
|---|---|---|---|---|---|---|---|
| Verastem IncVSTM | COM NEW | 92337C203 | 12.8 | 7.2% | 3,349,627 | Added+47,327 | |
| Evolus IncEOLS | COM | 30052C107 | 11.0 | 6.2% | 1,590,162 | Reduced−168,929 | |
| Tenax Therapeutics IncTENX | COM NEW | 88032L605 | 9.6 | 5.4% | 660,000 | Reduced−315,200 | |
| Nektar TherapeuticsNKTR | COM NEW | 640268306 | 8.4 | 4.8% | 120,654 | Added+35,654 | |
| Adma Biologics IncADMA | COM | 000899104 | 8.0 | 4.5% | 650,000 | Call | Reduced−500,000 |
| Adma Biologics IncADMA | COM | 000899104 | 6.2 | 3.5% | 740,000 | Unchanged | |
| CAMP4 Therapeutics CorpCAMP | COM 13469V AB 4 CAMTEK LTD NOTE 12/0 | 13463J101 | 6.1 | 3.4% | 1,389,622 | Unchanged | |
| Insmed IncINSM | COM PAR $.01 | 457669307 | 5.6 | 3.2% | 40,000 | Call | New+40,000 |
| Eloxx Pharmaceuticals IncELOX | COM NEW | 29014R301 | 5.5 | 3.1% | 397,160 | New+397,160 | |
| Ultragenyx Pharmaceutical inRARE | COM | 90400D108 | 5.5 | 3.1% | 200,000 | Call | New+200,000 |
| Kazia Therapeutics LtdKZIA | SPONSORED ADS | 48669G303 | 4.9 | 2.7% | 345,179 | Unchanged | |
| Medtronic plc | SHS | G5960L103 | 4.4 | 2.5% | 50,000 | Call | New+50,000 |
| Indivior Pharmaceuticals IncINDV | COM | 45579U109 | 4.1 | 2.3% | 100,000 | New+100,000 | |
| Corbus Pharmaceuticals HoldingsCRBP | COM NEW | 21833P301 | 4.0 | 2.2% | 425,000 | Added+41,538 | |
| Abbott LaboratoriesABT | COM | 002824100 | 3.8 | 2.1% | 40,000 | Call | New+40,000 |
| Satellos Bioscience IncMSLE | COM | 80401L803 | 3.7 | 2.1% | 491,624 | Added+391,624 | |
| Zevra Therapeutics IncZVRA | COM NEW | 488445206 | 3.7 | 2.1% | 258,701 | Reduced−221,299 | |
| Abeona Therapeutics IncABEO | COM NEW | 00289Y206 | 3.4 | 1.9% | 557,284 | Reduced−189,303 | |
| Boston Scientific CorpBSX | COM | 101137107 | 3.3 | 1.8% | 50,000 | Call | New+50,000 |
| Edesa Biotech IncEDSA | COM NEW | 27966L306 | 3.2 | 1.8% | 456,439 | Added+426,439 | |
| Evolus IncEOLS | COM | 30052C107 | 3.2 | 1.8% | 420,000 | Call | Unchanged |
| Biomarin Pharmaceutical IncBMRN | COM | 09061G101 | 3.1 | 1.8% | 50,000 | Call | New+50,000 |
| Cabaletta Bio IncCABA | COM | 12674W109 | 2.9 | 1.6% | 917,100 | Added+867,100 | |
| AN2 Therapeutics IncANTX | COM | 037326105 | 2.7 | 1.5% | 551,692 | Reduced−162,153 | |
| Xilio Therapeutics IncXLO | COM | 98422T209 | 2.2 | 1.2% | 225,994 | Added+161,832 | |
| Adicet Bio IncACET | COM NEW | 007002207 | 2.1 | 1.2% | 245,518 | Added+23,563 | |
| Xeris Biopharma Holdings IncXERS | COM | 98422E103 | 2.1 | 1.2% | 280,000 | Call | Unchanged |
| Tela Bio IncTELA | COM | 872381108 | 2.0 | 1.1% | 2,662,427 | Added+45,175 | |
| Aytu Biopharma IncAYTU | COM | 054754858 | 2.0 | 1.1% | 912,921 | Added+120,632 | |
| Curis Inc | COM | 231269309 | 1.7 | 1.0% | 3,312,185 | Reduced−414,221 | |
| Spruce Biosciences IncSPRB | COM NEW | 85209E208 | 1.6 | 0.9% | 28,795 | New+28,795 | |
| Heron Therapeutics IncHRTX | COM | 427746102 | 1.5 | 0.8% | 1,000,000 | Call | Unchanged |
| SI Bone IncSIBN | COM | 825704109 | 1.5 | 0.8% | 100,000 | Call | Unchanged |
| Okyo Pharma Ltd | SHS NEW | G6724L116 | 1.3 | 0.7% | 862,996 | Added+12,996 | |
| Neumora Therapeutics Inc.NMRA | COM | 640979100 | 1.3 | 0.7% | 500,000 | Call | Unchanged |
| Pasithea Therapeutics CorpKTTA | COM NEW | 70261F202 | 1.1 | 0.6% | 2,201,468 | Added+1,370,167 | |
| Sol-Gel Technologies Ltd | SHS NEW | M8694L137 | 1.1 | 0.6% | 14,469 | Reduced−13,309 | |
| Pulmonx CorpLUNG | COM | 745848101 | 1.1 | 0.6% | 815,436 | Added+47,148 | |
| X4 Pharmaceuticals IncXFOR | COM NEW | 98420X202 | 1.1 | 0.6% | 224,989 | Reduced−110,320 | |
| Ardelyx IncARDX | COM | 039697107 | 1.1 | 0.6% | 150,000 | Call | Unchanged |
| Delcath Sys IncDCTH | COM NEW | 24661P807 | 1.0 | 0.6% | 100,000 | Call | Unchanged |
| IN8BIO IncINAB | COM NEW | 45674E208 | 1.0 | 0.6% | 695,287 | Added+31,875 | |
| Moonlake ImmunotherapeuticsMLTX | CLASS A ORD | 61559X104 | 1.0 | 0.5% | 50,000 | New+50,000 | |
| Quoin Pharmaceuticals LtdQNRX | SPONSORED ADS | 74907L409 | 1.0 | 0.5% | 199,486 | Added+146,026 | |
| Maxcyte IncMXCT | COM | 57777K106 | 0.9 | 0.5% | 751,606 | Reduced−253,067 | |
| Phathom Pharmaceuticals IncPHAT | COM | 71722W107 | 0.9 | 0.5% | 85,010 | Added+35,000 | |
| Azitra IncAZTR | COM NEW | 05479L302 | 0.9 | 0.5% | 5,285,476 | New+5,285,476 | |
| Connect Biopharma Holdings Ltd | SHS | G23549101 | 0.9 | 0.5% | 364,254 | Added+54,254 | |
| Cybin Inc | COM NEW | 23256X407 | 0.9 | 0.5% | 129,280 | Reduced−4,780 | |
| Ultragenyx Pharmaceutical inRARE | COM | 90400D108 | 0.8 | 0.5% | 25,000 | New+25,000 | |
| Inhibikase Therapeutics IncIKT | COM NEW | 45719W205 | 0.8 | 0.5% | 396,179 | Reduced−561,023 | |
| Zentalis Pharmaceuticals IncZNTL | COM | 98943L107 | 0.8 | 0.4% | 161,583 | Reduced−107,517 | |
| Cytomx Therapeutics Inc.CTMX | COM | 23284F105 | 0.8 | 0.4% | 205,000 | Added+5,000 | |
| Mannkind CorpMNKD | COM NEW | 56400P706 | 0.8 | 0.4% | 250,000 | Call | Reduced−250,000 |
| Nuvectis Pharma IncNVCT | COM | 67080T108 | 0.7 | 0.4% | 40,000 | New+40,000 | |
| Crescent Biopharma Inc. | COM | G2545C104 | 0.7 | 0.4% | 40,000 | Reduced−45,000 | |
| PMV Pharmaceuticals IncPMVP | COM | 69353Y103 | 0.7 | 0.4% | 536,086 | Reduced−172,016 | |
| Oruka Therapeutics IncORKA | COM | 687604108 | 0.7 | 0.4% | 7,500 | New+7,500 | |
| Radiopharm Theranostics LtdRADX | SPONSORED ADS | 75041J101 | 0.7 | 0.4% | 51,000,000 | Unchanged | |
| Onkure Therapeutics IncOKUR | COM CL A | 68277Q105 | 0.6 | 0.3% | 130,684 | Reduced−1,894 | |
| Nervgen Pharma CorpNGEN | COM | 64082X203 | 0.6 | 0.3% | 271,678 | New+271,678 | |
| Calcimedica Inc | COM NEW | 38942Q202 | 0.5 | 0.3% | 622,432 | New+622,432 | |
| Arvinas IncARVN | COM | 04335A105 | 0.5 | 0.3% | 60,000 | Added+32,500 | |
| Bioage Labs IncBIOA | COM | 09077V100 | 0.5 | 0.3% | 20,000 | Reduced−30,000 | |
| Opus Genetics IncIRD | COM | 67577R102 | 0.4 | 0.2% | 100,718 | Added+32,030 | |
| QT Imaging Holdings IncQTI | COM | 746962307 | 0.4 | 0.2% | 100,000 | New+100,000 | |
| Boundless Bio IncBOLD | COM | 10170A100 | 0.4 | 0.2% | 154,595 | Reduced−443,087 | |
| Sintx Technologies IncSINT | COM NEW | 829392703 | 0.3 | 0.2% | 209,205 | New+209,205 | |
| Cellectar Biosciences IncCLRB | COM NEW | 15117F880 | 0.3 | 0.2% | 104,550 | New+104,550 | |
| Eupraxia Pharmaceuticals IncEPRX | COM 298736 AL 3 EURONET WORLDWIDE INC NOTE 0.750% 3/1 | 29842P105 | 0.3 | 0.2% | 43,491 | New+43,491 | |
| SAB Biotherapeutics IncSABS | COM NEW | 78397T202 | 0.3 | 0.2% | 73,271 | Added+23,271 | |
| Adlai Nortye LtdANL | SPONSORED ADS | 00704R109 | 0.3 | 0.2% | 24,257 | New+24,257 | |
| Senseonics Holdings IncSENS | COM | 81727U303 | 0.3 | 0.2% | 48,680 | New+48,680 | |
| Pliant Therapeutics IncPLRX | COM | 729139105 | 0.3 | 0.1% | 230,538 | Added+5,888 | |
| Codexis IncCDXS | COM | 192005106 | 0.2 | 0.1% | 109,662 | Reduced−308,332 | |
| Precision Optics Corp Inc MaPOCI | COM NEW | 740294400 | 0.2 | 0.1% | 46,390 | Reduced−53,610 | |
| Upstream Bio IncUPB | COM | 91678A107 | 0.2 | 0.1% | 33,432 | Reduced−1,568 | |
| Rein Therapeutics IncRNTX | COM NEW | 00887A204 | 0.2 | 0.1% | 218,038 | New+218,038 | |
| Heron Therapeutics IncHRTX | COM | 427746102 | 0.2 | 0.1% | 490,787 | Reduced−911,404 | |
| CNS Pharmaceuticals IncCNSP | COM | 18978H508 | 0.2 | 0.1% | 41,573 | Reduced−19,427 | |
| Humacyte IncHUMA | COM | 44486Q103 | 0.2 | 0.1% | 231,299 | New+231,299 | |
| Kalaris Therapeutics IncKLRS | COM | 482929106 | 0.1 | <0.1% | 30,122 | Added+9,722 | |
| Processa Pharmaceuticals IncPCSA | COM SHS | 74275C403 | 0.1 | <0.1% | 55,000 | Unchanged | |
| Bioatla IncBCAB | COM NEW | 09077B203 | 0.1 | <0.1% | 16,432 | New+16,432 | |
| Compugen Ltd | ORD | M25722105 | 0.1 | <0.1% | 31,387 | Reduced−72,913 | |
| Ovid Therapeutics IncOVID | COM | 690469101 | 0.1 | <0.1% | 21,300 | Reduced−18,700 | |
| Evaxion ASEVAX | SPONSORED ADS | 29970R303 | 0.1 | <0.1% | 17,562 | Reduced−2,151 |
Sold out: 21 positions
Held at the end of the quarter before and not reported this quarter.
| Issuer | Class | CUSIP | Reported value$ | Weight | Shares | Put or call | Change on the quarter before |
|---|---|---|---|---|---|---|---|
| Abeona Therapeutics IncABEO | COM NEW | 00289Y206 | 0.0 | 0.0% | 0 | Call | Sold out−100,000 |
| Acadia Pharmaceuticals IncACAD | COM | 004225108 | 0.0 | 0.0% | 0 | Call | Sold out−100,000 |
| Alexandria Real Estate Eq inARE | COM | 015271109 | 0.0 | 0.0% | 0 | Call | Sold out−50,000 |
| Bioatla Inc | COM | 09077B104 | 0.0 | 0.0% | 0 | Sold out−65,387 | |
| Candel Therapeutics IncCADL | COM | 137404109 | 0.0 | 0.0% | 0 | Sold out−102,500 | |
| Cytomx Therapeutics Inc.CTMX | COM | 23284F105 | 0.0 | 0.0% | 0 | Call | Sold out−200,000 |
| Eledon Pharmaceuticals IncELDN | COM | 28617K101 | 0.0 | 0.0% | 0 | Sold out−35,000 | |
| Establishment Labs Holdings Inc | COM | G31249108 | 0.0 | 0.0% | 0 | Call | Sold out−50,000 |
| Establishment Labs Holdings Inc | COM | G31249108 | 0.0 | 0.0% | 0 | Sold out−6,000 | |
| Janux Therapeutics IncJANX | COM | 47103J105 | 0.0 | 0.0% | 0 | Sold out−20,000 | |
| Mannkind CorpMNKD | COM NEW | 56400P706 | 0.0 | 0.0% | 0 | Sold out−16,300 | |
| Neumora Therapeutics Inc.NMRA | COM | 640979100 | 0.0 | 0.0% | 0 | Sold out−100,000 | |
| Omniab IncOABI | COM | 68218J103 | 0.0 | 0.0% | 0 | Sold out−164,045 | |
| SI Bone IncSIBN | COM | 825704109 | 0.0 | 0.0% | 0 | Sold out−14,964 | |
| SPDR Series Trust | STATE STREET SPD | 78464A870 | 0.0 | 0.0% | 0 | Call | Sold out−400,000 |
| SPDR Series Trust | STATE STREET SPD | 78464A870 | 0.0 | 0.0% | 0 | Put | Sold out−400,000 |
| Surrozen IncSRZN | COM NEW | 86889P208 | 0.0 | 0.0% | 0 | Sold out−33,005 | |
| Terns Pharmaceuticals Inc | COM | 880881107 | 0.0 | 0.0% | 0 | Call | Sold out−100,000 |
| Verrica Pharmaceuticals IncVRCA | COM SHS | 92511W207 | 0.0 | 0.0% | 0 | Sold out−99,735 | |
| Xeris Biopharma Holdings IncXERS | COM | 98422E103 | 0.0 | 0.0% | 0 | Sold out−40,030 | |
| Xoma Royalty Corporation | COM NEW | 98419J206 | 0.0 | 0.0% | 0 | Sold out−69,500 |
Source: SEC EDGAR, Form 13F-HR, accession 0001440771-26-000016 (on sec.gov). Last ingested by Listed: Oct 22, 2026, 05:26 ET. Listed shows no prices and gives no investment advice.