Sio Capital Management, LLC

Name: Sio Capital Management, LLC: Form 13F holdings for the quarter ended 2026-06-30
Creator: Listed

An institutional investment manager in NEW YORK, NY. Its Form 13F for the quarter ended Jun 30, 2026, filed Aug 14, 2026. SEC CIK 1482416.

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Reported value$604.3m
Positions59

Holdings: 59 positions

The filing on sec.gov

As filed, largest first. Reported value is what the manager stated for each position at the quarter end, in US dollars; it is filing data, not a price. Weight is the position's share of the total reported value. Changes compare with the 13F for the quarter ended 2026-03-31.

Sio Capital Management, LLC, holdings
Issuer	Class	CUSIP	Reported value$m	Weight	Shares	Put or call	Change on the quarter before
Anteris Technologies GlobalAVR	COM	03675P102	54.6	9.0%	5,545,984		Added+163,019
Cencora IncCOR	COM	03073E105	49.1	8.1%	173,588		Added+72,694
Maximus IncMMS	COM	577933104	38.5	6.4%	715,267		Reduced−53,558
Allogene Therapeutics IncALLO	COM	019770106	27.7	4.6%	13,323,431		New+13,323,431
Globus Med IncGMED	CL A	379577208	23.8	3.9%	301,816		New+301,816
GSK plcGSK	SPONSORED ADR	37733W204	22.9	3.8%	436,700		Added+50,821
Tyra Biosciences IncTYRA	COM	90240B106	22.2	3.7%	695,315		Added+89,876
Waystar HLDG CorpWAY	COM	946784105	19.0	3.1%	925,834		Reduced−716,402
Sellas Life Sciences Group ISLS	COM NEW	81642T209	18.2	3.0%	1,230,700	Put	New+1,230,700
Ideaya Biosciences IncIDYA	COM	45166A102	17.9	3.0%	480,383		New+480,383
Oruka Therapeutics IncORKA	COM	687604108	16.9	2.8%	177,118		Added+44,622
The Cigna GroupCI	COM	125523100	15.9	2.6%	57,750		New+57,750
Sanofi SASNY	SPONSORED ADR	80105N105	15.5	2.6%	364,200		Added+124,529
Icon Pub Ltd Co	SHS	G4705A100	15.3	2.5%	88,186		Reduced−218,172
Viatris IncVTRS	COM	92556V106	15.2	2.5%	954,299		New+954,299
Cross Ctry Healthcare Inc	COM	227483104	14.5	2.4%	1,098,393		Unchanged
Rapport Therapeutics IncRAPP	COM	75383L102	12.8	2.1%	307,657		Reduced−59,152
Abbott LaboratoriesABT	COM	002824100	11.7	1.9%	128,656		Reduced−57,918
Celcuity IncCELC	COM	15102K100	11.5	1.9%	110,022		Reduced−83,821
Zimmer Biomet Holdings IncZBH	COM	98956P102	11.3	1.9%	131,445		Added+68,832
Regeneron PharmaceuticalsREGN	COM	75886F107	11.2	1.9%	18,000		New+18,000
Bristol-Myers Squibb CoBMY	COM	110122108	11.1	1.8%	193,500		New+193,500
Medtronic plc	SHS	G5960L103	11.1	1.8%	142,500		New+142,500
VIR Biotechnology IncVIR	COM	92764N102	11.0	1.8%	1,075,274		Reduced−423,346
Senseonics Holdings IncSENS	COM	81727U303	9.0	1.5%	1,592,692		Added+1,476,908
Eyepoint IncEYPT	COM NEW	30233G209	8.9	1.5%	623,130		Reduced−98,655
Cybin Inc	COM NEW	23256X407	8.6	1.4%	1,300,000		New+1,300,000
ANI Pharmaceuticals IncANIP	COM	00182C103	8.1	1.3%	97,305		Reduced−168,238
Protara Therapeutics IncTARA	COM STK	74365U107	7.3	1.2%	1,921,872		Reduced−47,967
Relmada Therapeutics IncRLMD	COM	75955J402	6.9	1.1%	1,003,562		Added+38,562
Tango Therapeutics IncTNGX	COM	87583X109	6.5	1.1%	208,500		New+208,500
Aquestive Therapeutics IncAQST	COM	03843E104	6.2	1.0%	1,486,175		Reduced−436,712
Dianthus Therapeutics IncDNTH	COM	252828108	5.8	1.0%	59,254		Reduced−310,791
Sionna Therapeutics IncSION	COM	829401108	5.6	0.9%	127,808		Reduced−166,532
Ocular Therapeutix IncOCUL	COM	67576A100	5.3	0.9%	539,493		Reduced−429,104
Zenas Biopharma IncZBIO	COM	98937L105	5.3	0.9%	208,557		Reduced−123,173
Bright Minds Biosciences IncDRUG	COM NEW	10919W405	5.2	0.9%	73,952		Reduced−12,131
Onkure Therapeutics IncOKUR	COM CL A	68277Q105	4.9	0.8%	1,078,965		Unchanged
Savara IncSVRA	COM	805111101	3.8	0.6%	617,675		Added+3,787
PMV Pharmaceuticals IncPMVP	COM	69353Y103	3.5	0.6%	2,634,137		Reduced−442,443
Aveanna Healthcare Holdings IncAVAH	COM	05356F105	3.2	0.5%	369,036		New+369,036
Ovid Therapeutics IncOVID	COM	690469101	2.7	0.4%	1,005,334		Reduced−247,047
Immunome IncIMNM	COM	45257U108	2.6	0.4%	124,168		Reduced−40,942
Hims & Hers Health IncHIMS	COM CL A	433000106	2.6	0.4%	75,000	Call	New+75,000
AN2 Therapeutics IncANTX	COM	037326105	2.6	0.4%	529,933		Reduced−127,267
Serina Therapeutics IncSER	COM SHS	81751A108	1.9	0.3%	1,000,000		Unchanged
Aligos Therapeutics IncALGS	COM NEW	01626L204	1.9	0.3%	327,237		Unchanged
Ibio IncIBIO	COM NEW	451033708	1.6	0.3%	904,268		Unchanged
Xilio Therapeutics IncXLO	COM	98422T209	1.5	0.2%	152,464		Unchanged
Artivion IncAORT	COM	228903100	1.1	0.2%	48,481		New+48,481
Bridgebio Oncology TherapeutBBOT	COM NEW	107924102	1.0	0.2%	130,628		Unchanged
Tela Bio IncTELA	COM	872381108	0.5	<0.1%	636,300		Unchanged
Adagio Med Holdings IncADGM	COM	00534B100	0.5	<0.1%	698,989		Reduced−589,472
Neuroone Med Technologies CoNMTC	COM	64130M308	0.3	<0.1%	82,767		New+82,767
Enveric Biosciences IncENVB	COM SHS	29405E505	0.2	<0.1%	180,000		New+180,000
Modular Med IncMODD	COM NEW	60785L306	0.1	<0.1%	26,190		Unchanged
QT Imaging Holdings IncQTI	COM	746962307	0.1	<0.1%	15,236		New+15,236
Rocket Pharmaceuticals Inc	*W EXP 09/02/202	77313F114	0.0	<0.1%	400,000		Unchanged
Humacyte Inc	*W EXP 08/27/202	44486Q111	0.0	<0.1%	49,998		Unchanged

Sold out: 34 positions

Held at the end of the quarter before and not reported this quarter.

Sio Capital Management, LLC, positions sold out
Issuer	Class	CUSIP	Weight	Put or call	Change on the quarter before
Abivax SAABVX	SPONSORED ADS	00370M103	0.0%		Sold out−135,800
Biohaven Ltd	COM	G1110E107	0.0%		Sold out−1,163,926
Biomarin Pharmaceutical IncBMRN	COM	09061G101	0.0%		Sold out−194,226
Boundless Bio IncBOLD	COM	10170A100	0.0%		Sold out−163,679
Centene Corp DelCNC	COM	15135B101	0.0%	Put	Sold out−100,000
Compass Pathways plcCMPS	SPONSORED ADS	20451W101	0.0%		Sold out−1,506,525
Context Therapeutics IncCNTX	COM	21077P108	0.0%		Sold out−917,922
Corcept Therapeutics IncCORT	COM	218352102	0.0%		Sold out−674,759
Crinetics Pharmaceuticals in	COM	22663K107	0.0%		Sold out−249,887
Disc Medicine IncIRON	COM	254604101	0.0%		Sold out−65,203
Edgewise Therapeutics IncEWTX	COM	28036F105	0.0%		Sold out−268,986
Elicio Therapeutics IncELTX	COM	28657F103	0.0%	Put	Sold out−11,700
Embecta CorpEMBC	COMMON STOCK	29082K105	0.0%		Sold out−1,847,850
Enanta Pharmaceuticals IncENTA	COM	29251M106	0.0%		Sold out−40,000
Erasca IncERAS	COM	29479A108	0.0%		Sold out−5,000
Foghorn Therapeutics IncFHTX	COM	344174107	0.0%		Sold out−122,889
Haemonetics Corp MassHAE	COM	405024100	0.0%		Sold out−220,672
Hyperfine IncHYPR	COM CL A	44916K106	0.0%		Sold out−1,000,000
Integra Lifesciences Holdings CIART	COM NEW	457985208	0.0%		Sold out−383,140
Kymera Therapeutics IncKYMR	COM	501575104	0.0%		Sold out−32,235
Livanova plc	SHS	G5509L101	0.0%		Sold out−421,615
Monopar Therapeutics IncMNPR	COM NEW	61023L207	0.0%		Sold out−173,506
Neuroone Med Technologies Co	COM NEW	64130M209	0.0%		Sold out−496,614
Nyxoah S a	SHS	B6S7WD106	0.0%		Sold out−50,839
Organon & CoOGN	COMMON STOCK	68622V106	0.0%		Sold out−865,908
Oscar Health IncOSCR	CL A	687793109	0.0%	Put	Sold out−3,000
Proqr Therapeutics N V	SHS EURO	N71542109	0.0%		Sold out−1,954,715
Quidelortho CorpQDEL	COM	219798105	0.0%		Sold out−359,011
Replimune Group IncREPL	COM	76029N106	0.0%		Sold out−720,036
Shoulder Innovations IncSI	COMMON STOCK	82537J108	0.0%		Sold out−210,641
Simulations Plus Inc	COM	829214105	0.0%		Sold out−200
Structure Therapeutics IncGPCR	SPONSORED ADS	86366E106	0.0%		Sold out−209,093
Teleflex IncorporatedTFX	COM	879369106	0.0%		Sold out−94,800
Terns Pharmaceuticals Inc	COM	880881107	0.0%		Sold out−10,100

Source: SEC EDGAR, Form 13F-HR, accession 0001214659-26-010311 (on sec.gov). Last ingested by Listed: Oct 22, 2026, 05:26 ET. Listed shows no prices and gives no investment advice.