Listed

Sofinnova Investments, Inc.

An institutional investment manager in Menlo Park, CA. Its Form 13F for the quarter ended Jun 30, 2026, filed Aug 14, 2026. SEC CIK 1631134.

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Holdings: 57 positions

The filing on sec.gov

As filed, largest first. Reported value is what the manager stated for each position at the quarter end, in US dollars; it is filing data, not a price. Weight is the position's share of the total reported value. Changes compare with the 13F for the quarter ended 2026-03-31.

Sofinnova Investments, Inc., holdings
IssuerClassCUSIPReported value$mWeightSharesPut or callChange on the quarter before
Natera IncNTRACOM63230710442121.8%1,550,280Unchanged
Vera Therapeutics IncVERACL A92337R1011206.2%2,793,987Unchanged
Genmab A/SGMABSPONSORED ADS3723032061115.7%4,045,215Added+3,292,954
Jazz Pharmaceuticals PLCSHS USDG5087110588.04.6%365,341Reduced−232,986
Rapport Therapeutics IncRAPPCOM75383L10279.44.1%1,904,408Unchanged
Seaport Therapeutics IncSPTXCOM81221K10877.44.0%3,564,871New+3,564,871
Arrivent BioPharma IncAVBPCOM04272N10258.93.0%1,696,752Unchanged
Ultragenyx Pharmaceutical InRARECOM90400D10857.33.0%1,717,505Reduced−1,428,383
BioAge Labs IncBIOACOM09077V10056.22.9%2,293,788Unchanged
Bristol-Myers Squibb CoBMYCOM11012210850.52.6%876,970Reduced−1,111,751
Supernus PharmaceuticalsSUPNCOM86845910848.22.5%1,036,328Added+82,019
Rhythm Pharmaceuticals IncRYTMCOM76243J10545.32.3%408,027Reduced−42,069
Gilead Sciences IncGILDCOM37555810343.32.2%343,100New+343,100
United Therapeutics Corp DelUTHRCOM91307C10241.42.1%76,489Reduced−83,581
Cogent Biosciences IncCOGTCOM19240Q20140.12.1%1,035,148Reduced−1,078,403
Axsome Therapeutics Inc.AXSMCOM05464T10439.32.0%160,429Reduced−52,318
Immatics N.VSHSN4444510937.21.9%3,669,346Added+38,892
Dyne Therapeutics IncDYNCOM26818M10836.81.9%1,658,384Added+24,487
Immunome IncIMNMCOM45257U10836.51.9%1,720,316Added+18,412
IDEAYA Biosciences IncIDYACOM45166A10234.51.8%925,119Reduced−206,667
Anaptysbio IncANABCOM03272410633.31.7%493,536Added+245,283
Nektar TherapeuticsNKTRCOM NEW64026830632.91.7%471,763Reduced−37,783
Pharvaris N VCOMN6960510830.51.6%881,299Added+62,971
Arcus Biosciences IncRCUSCOM03969F10929.21.5%945,690Added+22,604
Inhibrx Biosciences IncINBXCOM45720N10328.71.5%303,103Reduced−102,926
BioMarin Pharmaceutical IncBMRNCOM09061G10120.51.1%358,568Reduced−423,414
Veradermics IncMANECOMMON STOCK92296710418.30.9%148,993Added+75,678
Alcon AGORD SHSH0130112817.20.9%255,824Reduced−474,148
Insmed IncINSMCOM PAR $.0145766930716.90.9%158,398Reduced−187,677
Ultragenyx Pharmaceutical InRARECOM90400D10816.70.9%500,000CallAdded+150,000
Intuitive Surgical IncISRGCOM NEW46120E60215.90.8%40,000CallNew+40,000
Globus Med IncGMEDCL A37957720815.80.8%200,000CallNew+200,000
Edgewise Therapeutics IncEWTXCOM28036F10515.50.8%380,923Reduced−5,575
Exelixis IncEXELCOM30161Q10413.80.7%254,200PutAdded+2,700
Nurix Therapeutics IncNRIXCOM67080M10312.70.7%524,098New+524,098
Design Therapeutics IncDSGNCOM25056L10312.50.6%865,135New+865,135
Definium Therapeutics IncDFTXCOM SHS24477V10512.00.6%255,903Reduced−88,263
First Tracks BiotherapeuticsTRAXORD SHS33718510211.40.6%565,199New+565,199
Abbott LaboratoriesABTCOM00282410011.20.6%122,998New+122,998
Disc Medicine IncIRONCOM25460410110.70.6%146,239Added+67,919
Tenax Therapeutics IncTENXCOM NEW88032L6057.30.4%500,039Added+395,639
Sionna Therapeutics IncSIONCOM8294011086.40.3%144,432New+144,432
Absci CorporationABSICOM00091E1093.90.2%337,400New+337,400
Mirum Pharmaceuticals IncMIRMCOM6047491013.20.2%27,591Unchanged
Jade Biosciences IncJBIOCOM0080642062.40.1%107,391Unchanged
Savara IncSVRACOM8051111012.20.1%364,763Unchanged
Praxis Precision Medicines IPRAXCOM NEW74006W2072.20.1%6,440Reduced−57,240
Septerna IncSEPNCOM81734D1041.6<0.1%47,506Unchanged
Onkure Therapeutics IncOKURCOM CL A68277Q1051.5<0.1%321,692Added+179,992
Sagimet Biosciences IncSGMTCOM SER A7867001041.3<0.1%166,667New+166,667
Wave Life Sciences LtdSHSY953081051.1<0.1%189,253Unchanged
Aktis Oncology IncAKTSCOM01021M1041.0<0.1%32,436New+32,436
Tyra Biosciences IncTYRACOM90240B1061.0<0.1%32,267Reduced−171,748
Bolt Biotherapeutics IncBOLTCOM0977022030.5<0.1%137,721Unchanged
Nextcure IncNXTCCOM65343E2070.4<0.1%222,654Unchanged
ImageneBio IncIMACOM45175G2070.2<0.1%31,884Unchanged
Heartflow IncHTFLCOM42238D1070.1<0.1%5,079New+5,079

Sold out: 30 positions

Held at the end of the quarter before and not reported this quarter.

Sofinnova Investments, Inc., positions sold out
IssuerClassCUSIPReported value$WeightSharesPut or callChange on the quarter before
Acadia Pharmaceuticals IncACADCOM0042251080.00.0%0Sold out−78,551
AstraZeneca PLCORDG0593M1070.00.0%0Sold out−456,031
AxoGen IncAXGNCOM05463X1060.00.0%0Sold out−210,665
Axsome Therapeutics Inc.AXSMCOM05464T1040.00.0%0PutSold out−200,000
Biogen IncBIIBCOM09062X1030.00.0%0Sold out−229,521
BridgeBio Pharma IncBBIOCOM10806X1020.00.0%0Sold out−409,183
Celcuity IncCELCCOM15102K1000.00.0%0PutSold out−300,000
Celcuity IncCELCCOM15102K1000.00.0%0Sold out−366,175
Compass Therapeutics IncCMPXCOM20454B1040.00.0%0Sold out−2,056,161
Compass Therapeutics IncCMPXCOM20454B1040.00.0%0CallSold out−500,000
Cytokinetics IncCYTKCOM23282W6050.00.0%0Sold out−91,791
Dexcom IncDXCMCOM2521311070.00.0%0Sold out−393,576
Establishment Labs Hldgs IncCOMG312491080.00.0%0Sold out−33,930
Harmony Biosciences Hldgs IncHRMYCOM4131971040.00.0%0Sold out−152,695
Invesco QQQ TRUNIT SER 146090E1030.00.0%0PutSold out−150,000
iShares TRISHARES BIOTECH4642875560.00.0%0PutSold out−475,000
iShares TRRUSSELL 2000 ETF4642876550.00.0%0PutSold out−600,000
Liquidia CorporationLQDACOM53635D2020.00.0%0PutSold out−500,000
Oric Pharmaceuticals IncORICCOM68622P1090.00.0%0Sold out−679,578
Pfizer IncPFECOM7170811030.00.0%0CallSold out−800,000
Replimune Group IncREPLCOM76029N1060.00.0%0CallSold out−1,015,400
Roivant Sciences LtdSHSG762791010.00.0%0Sold out−477,995
Soleno Therapeutics IncCOM8342033090.00.0%0Sold out−14,689
SPDR Series TrustSTATE STREET SPD78464A8700.00.0%0PutSold out−1,050,000
Stryker CorporationSYKCOM8636671010.00.0%0Sold out−44,480
Tango Therapeutics IncTNGXCOM87583X1090.00.0%0Sold out−395,081
United Therapeutics CorpUTHRCOM91307C1020.00.0%0PutSold out−80,300
Vaxcyte IncPCVXCOM92243G1080.00.0%0Sold out−50,600
Xenon Pharmaceuticals IncXENECOM98420N1050.00.0%0Sold out−305,216
Zymeworks IncZYMECOM98985Y1080.00.0%0Sold out−1,610

Source: SEC EDGAR, Form 13F-HR, accession 0001104659-26-096982 (on sec.gov). Last ingested by Listed: Oct 22, 2026, 05:26 ET. Listed shows no prices and gives no investment advice.