Ikarian Capital, LLC

Name: Ikarian Capital, LLC: Form 13F holdings for the quarter ended 2026-06-30
Creator: Listed

An institutional investment manager in DALLAS, TX. Its Form 13F for the quarter ended Jun 30, 2026, filed Aug 14, 2026. SEC CIK 1778253.

Share this page

Link

Story card, 1080 × 1920

Reported value$928.2m
Positions156

Holdings: 156 positions

The filing on sec.gov

As filed, largest first. Reported value is what the manager stated for each position at the quarter end, in US dollars; it is filing data, not a price. Weight is the position's share of the total reported value. Changes compare with the 13F for the quarter ended 2026-03-31.

Ikarian Capital, LLC, holdings
Issuer	Class	CUSIP	Reported value$m	Weight	Shares	Put or call	Change on the quarter before
SPDR Series Trust	ST STR SP BIOT	78464A870	47.5	5.1%	300,000	Put	Reduced−500,000
Abivax SAABVX	SPONSORED ADS	00370M103	45.5	4.9%	341,100	Call	Added+47,800
Abivax SAABVX	SPONSORED ADS	00370M103	43.4	4.7%	328,635		Added+271,000
Kodiak Sciences IncKOD	COM	50015M109	41.3	4.4%	1,059,730		Reduced−206,065
Abivax SAABVX	SPONSORED ADS	00370M103	33.3	3.6%	250,000	Put	New+250,000
Ionis Pharmaceuticals IncIONS	COM	462222100	31.7	3.4%	400,000	Call	Added+287,900
Moderna IncMRNA	COM	60770K107	28.0	3.0%	400,000	Put	New+400,000
Alumis IncALMS	COM	022307102	24.5	2.6%	870,548		Reduced−343,000
Praxis Precision Medicines IPRAX	COM NEW	74006W207	24.4	2.6%	72,842		Added+1,261
Ionis Pharmaceuticals IncIONS	COM	462222100	23.8	2.6%	300,000	Put	New+300,000
Vaxcyte IncPCVX	COM	92243G108	22.6	2.4%	388,682		Reduced−40,000
ANI Pharmaceuticals IncANIP	COM	00182C103	22.5	2.4%	272,085		Added+125,000
Celldex Therapeutics Inc NewCLDX	COM NEW	15117B202	17.8	1.9%	478,500		Added+17,253
Arcus Biosciences IncRCUS	COM	03969F109	15.6	1.7%	504,559		New+504,559
Relmada Therapeutics IncRLMD	COM	75955J402	14.9	1.6%	2,148,359		Reduced−540,000
Capricor Therapeutics IncCAPR	COM NEW	14070B309	14.5	1.6%	604,215		Added+76,200
Cogent Biosciences IncCOGT	COM	19240Q201	14.3	1.5%	370,084		New+370,084
Newamsterdam Pharma Company	PUT	N62509959	13.6	1.5%	400,000	Put	New+400,000
Vera Therapeutics IncVERA	CL A	92337R101	13.3	1.4%	310,000		Added+110,000
Contineum Therapeutics IncCTNM	CL A	21217B100	13.2	1.4%	807,874		Unchanged
Tenax Therapeutics IncTENX	COM NEW	88032L605	11.5	1.2%	787,600		Reduced−230,000
C4 Therapeutics IncCCCC	COM STK	12529R107	11.4	1.2%	2,433,000		New+2,433,000
Maze Therapeutics IncMAZE	COM	578784100	11.3	1.2%	378,999		Unchanged
Biohaven Ltd	COM	G1110E107	11.1	1.2%	748,181		Added+335,700
Connect Biopharma Holdings Ltd	SHS	G23549101	10.8	1.2%	4,538,534		Reduced−849,952
Alto Neuroscience IncANRO	COM SHS	02157Q109	10.7	1.2%	407,338		Reduced−107,662
Pharvaris N V	COM	N69605108	10.7	1.2%	308,856		Reduced−178,000
Alumis IncALMS	COM	022307102	10.0	1.1%	356,300	Call	Added+91,700
Jade Biosciences IncJBIO	COM NEW	008064206	9.5	1.0%	427,349		Reduced−85,000
Damora Therapeutics Inc	COM NEW	36322Q206	8.7	0.9%	335,710		Unchanged
Kodiak Sciences IncKOD	COM	50015M109	8.5	0.9%	217,700	Call	Added+117,700
Capricor Therapeutics IncCAPR	COM NEW	14070B309	8.4	0.9%	350,000	Call	Unchanged
Arrowhead Pharmaceuticals inARWR	COM	04280A100	8.2	0.9%	100,000	Put	Added+42,500
Viridian Therapeutics IncVRDN	COM	92790C104	7.8	0.8%	425,000		New+425,000
Pelthos Therapeutics IncPTHS	COM SHS	171126204	7.3	0.8%	256,598		Unchanged
Zura Bio Ltd	CLASS A ORD SHS	G9TY5A101	7.2	0.8%	1,218,492		Added+25,000
Tectonic Therapeutic IncTECX	COM	878972108	7.1	0.8%	205,837		Added+48,300
Praxis Precision Medicines IPRAX	COM NEW	74006W207	6.7	0.7%	20,000	Call	New+20,000
Spruce Biosciences IncSPRB	COM NEW	85209E208	6.6	0.7%	121,356		Unchanged
Hims & Hers Health IncHIMS	COM CL A	433000106	6.5	0.7%	188,381		New+188,381
Enliven Therapeutics IncELVN	COM	29337E102	6.4	0.7%	126,541		New+126,541
Proqr Thrapeutics N V	SHS EURO	N71542109	6.4	0.7%	3,425,930		Added+1,933,701
Bright Minds Biosciences IncDRUG	COM NEW	10919W405	6.2	0.7%	88,951		Reduced−77,696
Ovid Therapeutics IncOVID	COM	690469101	6.1	0.7%	2,269,704		Reduced−625,000
Ocugen IncOCGN	COM	67577C105	6.1	0.7%	3,962,972		Unchanged
Alpha Cognition IncACOG	COM NEW	02074J501	6.0	0.7%	836,259		Reduced−220,000
Kymera Therapeutics IncKYMR	COM	501575104	5.8	0.6%	50,400	Put	Unchanged
Harrow IncHROW	COM	415858109	5.8	0.6%	135,775		Reduced−407,272
Kazia Therapeutics LtdKZIA	SPONSORED ADS	48669G303	5.6	0.6%	396,201		New+396,201
Ultragenyx Pharmaceutical inRARE	COM	90400D108	5.5	0.6%	165,617		Reduced−316,954
Q32 Bio IncQTTB	COM	746964105	5.5	0.6%	430,000		New+430,000
Tenax Therapeutics IncTENX	COM NEW	88032L605	5.4	0.6%	373,100	Call	Added+258,800
Eupraxia Pharmaceuticals IncEPRX	COM	29842P105	5.4	0.6%	809,741		Reduced−405,000
Eyepoint IncEYPT	COM NEW	30233G209	5.3	0.6%	370,400	Put	Unchanged
Eyepoint IncEYPT	COM NEW	30233G209	5.3	0.6%	370,400	Call	Unchanged
Sellas Life Sciences Group ISLS	COM NEW	81642T209	5.2	0.6%	354,700	Put	New+354,700
Bioage Labs IncBIOA	COM	09077V100	4.9	0.5%	200,000		New+200,000
Rezolute IncRZLT	COM NEW	76200L309	4.9	0.5%	935,012		Added+918,533
Olema Pharmaceuticals IncOLMA	COM	68062P106	4.8	0.5%	383,281		Reduced−215,000
Sionna Therapeutics IncSION	COM	829401108	4.7	0.5%	107,500	Put	New+107,500
Monopar Therapeutics IncMNPR	COM NEW	61023L207	4.4	0.5%	47,861		New+47,861
Bridgebio Pharma IncBBIO	COM	10806X102	4.3	0.5%	57,417		Reduced−102,703
Celldex Therapeutics Inc NewCLDX	COM NEW	15117B202	4.2	0.5%	114,000	Put	Unchanged
Inventiva SAIVA	ADS	46124U107	4.2	0.4%	1,129,101		Reduced−300,000
Absci CorporationABSI	COM	00091E109	4.1	0.4%	353,772		New+353,772
Alector IncALEC	COM	014442107	4.0	0.4%	1,982,606		Reduced−100,000
Climb Bio IncCLYM	COM	28658R106	3.9	0.4%	300,000		New+300,000
Fulcrum Therapeutics IncFULC	COM	359616109	3.8	0.4%	1,049,161		Unchanged
Cardiol Therapeutics IncCRDL	COM CL A	14161Y200	3.5	0.4%	3,325,000		Added+600,000
CUE Biopharma IncCUE	COM	22978P205	3.3	0.4%	104,364		New+104,364
Cumberland Pharmaceuticals ICPIX	COM	230770109	3.3	0.4%	503,153		Reduced−50,000
Arrowhead Pharmaceuticals inARWR	COM	04280A100	3.1	0.3%	38,278		New+38,278
Vera Therapeutics IncVERA	CL A	92337R101	3.1	0.3%	71,700	Call	Unchanged
Rein Therapeutics IncRNTX	COM NEW	00887A204	3.1	0.3%	2,950,000		New+2,950,000
Arvinas IncARVN	COM	04335A105	3.0	0.3%	358,257		Unchanged
Acumen Pharmaceuticals IncABOS	COM	00509G209	2.8	0.3%	1,053,797		Unchanged
Promis Neurosciences IncPMN	COM SHS	74346M505	2.7	0.3%	205,000		Added+150,000
Q32 Bio IncQTTB	COM	746964105	2.5	0.3%	200,000	Put	New+200,000
Olema Pharmaceuticals IncOLMA	COM	68062P106	2.5	0.3%	200,000	Call	Reduced−349,800
Annexon IncANNX	COM	03589W102	2.5	0.3%	430,244		Reduced−150,000
Bristol-Myers Squibb CoBMY	COM	110122108	2.4	0.3%	42,500	Put	Reduced−457,500
Lexeo Therapeutics IncLXEO	COM	52886X107	2.4	0.3%	513,011		Unchanged
Delcath Sys IncDCTH	COM NEW	24661P807	2.3	0.3%	185,667		Reduced−245,584
Invivyd IncIVVD	COM	00534A102	2.3	0.2%	2,656,570		Unchanged
Uniqure NV	CALL	N90064901	2.3	0.2%	49,800	Call	Reduced−305,200
Cabaletta Bio IncCABA	COM	12674W109	2.2	0.2%	700,000		Reduced−200,000
Neumora Therapeutics Inc.NMRA	COM	640979100	2.2	0.2%	1,278,408		Unchanged
Amylyx Pharmaceuticals IncAMLX	COM	03237H101	2.1	0.2%	117,500		New+117,500
Tarsus Pharmaceuticals IncTARS	COM	87650L103	2.0	0.2%	31,166		Unchanged
Silence Therapeutics plcSLN	ADS	82686Q101	1.8	0.2%	830,784		Reduced−35,000
Journey Med CorpDERM	COM	48115J109	1.8	0.2%	251,436		Unchanged
DBV Technologies S aDBVT	SPONSORED ADS	23306J309	1.7	0.2%	525,000		Unchanged
Ibio IncIBIO	COM NEW	451033708	1.7	0.2%	957,062		Unchanged
Avalo Therapeutics IncAVTX	COM NEW	05338F306	1.7	0.2%	90,183		New+90,183
Anteris Technologies GlobalAVR	COM	03675P102	1.6	0.2%	166,571		Reduced−200,000
Palisade Bio IncPALI	COM	696389402	1.6	0.2%	750,000		Added+475,022
Amanat Acquisition Corp	CL A ORD	G0375M101	1.5	0.2%	150,000		New+150,000
Kalaris Therapeutics IncKLRS	COM	482929106	1.5	0.2%	360,000		Unchanged
Quince Therapeutics IncIRLA	COM	22053A305	1.3	0.1%	72,251		New+72,251
Lipocine Inc NewLPCN	COM NEW	53630X203	1.3	0.1%	508,556		Unchanged
Immunome IncIMNM	COM	45257U108	1.3	0.1%	60,000		New+60,000
Pliant Therapeutics IncPLRX	COM	729139105	1.1	0.1%	1,000,000		New+1,000,000
Immunic IncIMUX	COM NEW	4525EP200	1.0	0.1%	67,464		New+67,464
Quoin Pharmaceuticals LtdQNRX	SPONSORED ADS	74907L409	1.0	0.1%	211,538		Unchanged
Disc Medicine IncIRON	COM	254604101	1.0	0.1%	13,300	Call	New+13,300
Disc Medicine IncIRON	COM	254604101	1.0	0.1%	13,300	Put	New+13,300
Equillium IncEQ	COM	29446K106	1.0	0.1%	303,555		Unchanged
Neuronetics IncSTIM	COM	64131A105	0.9	<0.1%	701,182		Unchanged
Faeth Therapeutics IncFTH	COM NEW	81728A207	0.9	<0.1%	35,386		Added+29,035
Fractyl Health Inc	COM	35168W103	0.9	<0.1%	1,100,000		Unchanged
Cybin Inc	COM NEW	23256X407	0.9	<0.1%	132,153		Unchanged
First Tracks BiotherapeuticsTRAX	ORD SHS	337185102	0.9	<0.1%	42,775		New+42,775
Verastem IncVSTM	COM NEW	92337C203	0.8	<0.1%	213,865		Unchanged
Direxion Shares ETF Trust	DAI BIO BEA ETF	25461H853	0.8	<0.1%	105,822		Unchanged
Pepgen IncPEPG	COM	713317105	0.8	<0.1%	447,165		Unchanged
Acadia Pharmaceuticals IncACAD	COM	004225108	0.7	<0.1%	28,099		Unchanged
CNS Pharmaceuticals IncCNSP	COM	18978H508	0.6	<0.1%	135,830		Added+90,000
Lyell Immunopharma IncLYEL	COM NEW	55083R203	0.6	<0.1%	41,081		Unchanged
Wave Life Sciences Ltd	SHS	Y95308105	0.5	<0.1%	85,285		Unchanged
Immatics N.V	SHS	N44445109	0.5	<0.1%	48,569		Unchanged
Passage Bio IncPASG	COM NEW	702712209	0.5	<0.1%	99,517		Added+31,393
Nextcure IncNXTC	COM NEW	65343E207	0.5	<0.1%	288,303		Added+50,000
Forte Biosciences Inc	COM NEW	34962G208	0.4	<0.1%	20,972		Reduced−98,000
Solid Biosciences IncSLDB	COM NEW	83422E204	0.4	<0.1%	42,956		Reduced−221,453
Elicio Therapeutics IncELTX	COM	28657F103	0.4	<0.1%	107,100	Call	New+107,100
Elicio Therapeutics IncELTX	COM	28657F103	0.4	<0.1%	107,100	Put	New+107,100
Traws Pharma IncTRAW	COM NEW	68232V884	0.4	<0.1%	478,142		Reduced−200,000
Lexicon Pharmaceuticals IncLXRX	COM NEW	528872302	0.4	<0.1%	164,674		Unchanged
Elicio Therapeutics IncELTX	COM	28657F103	0.4	<0.1%	100,000		New+100,000
Adlai Nortye LtdANL	SPONSORED ADS	00704R109	0.4	<0.1%	33,899		Unchanged
Inmed Pharmaceuticals IncINM	COM NEW	457637700	0.4	<0.1%	245,025		New+245,025
Viking Therapeutics IncVKTX	COM	92686J106	0.4	<0.1%	9,717		Unchanged
Macrogenics IncMGNX	COM	556099109	0.3	<0.1%	74,893		Unchanged
Praxis Precision Medicines IPRAX	COM NEW	74006W207	0.3	<0.1%	900	Put	New+900
Tenax Therapeutics IncTENX	COM NEW	88032L605	0.2	<0.1%	16,500	Put	New+16,500
Hyperliquid Strategies IncPURR	COM	44916Y106	0.2	<0.1%	30,001		Unchanged
Evaxion ASEVAX	SPONSORED ADS	29970R303	0.2	<0.1%	74,698		Unchanged
Cartesian Therapeutics IncRNAC	COM NEW	816212302	0.2	<0.1%	20,807		Unchanged
Compass Pathways plcCMPS	SPONSORED ADS	20451W101	0.2	<0.1%	15,000		Reduced−660,000
Neuphoria Therapeutics IncNEUP	COM	64136E102	0.2	<0.1%	47,443		Unchanged
Voyager Therapeutics IncVYGR	COM	92915B106	0.2	<0.1%	53,063		Unchanged
Vyne Therapeutics Inc	COM	92941V308	0.2	<0.1%	264,912		Unchanged
Biocryst Pharmaceuticals IncBCRX	COM	09058V103	0.2	<0.1%	16,756		New+16,756
Enveric Biosciences IncENVB	COM SHS	29405E505	0.1	<0.1%	100,002		New+100,002
PMV Pharmaceuticals IncPMVP	COM	69353Y103	0.1	<0.1%	89,136		Unchanged
Vistagen Therapeutics IncVTGN	COM	92840H400	0.1	<0.1%	519,077		Unchanged
Chemomab Therapeutics LtdCMMB	SPONSORED ADS	16385C203	0.1	<0.1%	51,793		Unchanged
Nyxoah S a	SHS	B6S7WD106	0.1	<0.1%	47,358		Unchanged
Airsculpt Technologies IncAIRS	COM	009496100	0.1	<0.1%	16,398		Unchanged
Mangoceuticals IncMGRX	COM NEW	56270V205	0.1	<0.1%	138,146		Unchanged
Compass Therapeutics IncCMPX	COM	20454B104	0.0	<0.1%	18,000		Unchanged
Theriva Biologics IncTOVX	COM NEW	87164U508	0.0	<0.1%	112,076		Unchanged
Glucotrack Inc	COM NEW	45824Q804	0.0	<0.1%	45,830		Unchanged
Aethlon Med Inc	COM NEW	00808Y604	0.0	<0.1%	14,364		Unchanged
Jasper Therapeutics IncJSPR	COM NEW	471871202	0.0	<0.1%	24,093		Unchanged
Biomx Inc	COM NEW	09090D509	0.0	<0.1%	19,473		Unchanged

Sold out: 46 positions

Held at the end of the quarter before and not reported this quarter.

Ikarian Capital, LLC, positions sold out
Issuer	Class	CUSIP	Weight	Put or call	Change on the quarter before
ANI Pharmaceuticals IncANIP	COM	00182C103	0.0%	Call	Sold out−150,000
Autonomix Med Inc	COM NEW	05330T205	0.0%		Sold out−18,688
Avalo Therapeutics IncAVTX	COM NEW	05338F306	0.0%	Put	Sold out−158,500
Avalo Therapeutics IncAVTX	COM NEW	05338F306	0.0%	Call	Sold out−401,500
Bridgebio Oncology TherapeutBBOT	COM NEW	107924102	0.0%		Sold out−270,231
Bridgebio Pharma IncBBIO	COM	10806X102	0.0%	Call	Sold out−58,500
Centessa Pharmaceuticals plc	SPONSORED ADS	152309100	0.0%		Sold out−18,113
Connect Biopharma Holdings Ltd	SHS	G23549101	0.0%	Call	Sold out−144,600
Cytokinetics IncCYTK	COM NEW	23282W605	0.0%		Sold out−283,572
Cytokinetics IncCYTK	COM NEW	23282W605	0.0%	Put	Sold out−550,500
Cytokinetics IncCYTK	COM NEW	23282W605	0.0%	Call	Sold out−408,400
Definium Therapeutics IncDFTX	COM SHS	24477V105	0.0%		Sold out−58,803
ELI Lilly & CoLLY	COM	532457108	0.0%		Sold out−6,547
Enliven Therapeutics IncELVN	COM	29337E102	0.0%	Put	Sold out−83,700
Immunic Inc	COM	4525EP101	0.0%		Sold out−674,662
Insmed IncINSM	COM PAR $.01	457669307	0.0%		Sold out−4,214
Invesco QQQ TR	UNIT SER 1	46090E103	0.0%	Put	Sold out−100,000
IO Biotech Inc	COM	449778109	0.0%		Sold out−1,386,565
Ionis Pharmaceuticals IncIONS	COM	462222100	0.0%		Sold out−127,038
Ishares TR	RUSSELL 2000 ETF	464287655	0.0%	Put	Sold out−200,000
Jazz Pharmaceuticals plc	SHS USD	G50871105	0.0%		Sold out−12,460
Kalvista Pharmaceuticals Inc	COM	483497103	0.0%		Sold out−35,119
Karyopharm Therapeutics IncKPTI	COM NEW	48576U205	0.0%	Put	Sold out−920,000
Karyopharm Therapeutics IncKPTI	COM NEW	48576U205	0.0%		Sold out−733,435
Karyopharm Therapeutics IncKPTI	COM NEW	48576U205	0.0%	Call	Sold out−920,000
Kezar Life Sciences Inc	COM NEW	49372L209	0.0%		Sold out−102,211
Legend Biotech CorpLEGN	SPONSORED ADS	52490G102	0.0%		Sold out−226,888
Maze Therapeutics IncMAZE	COM	578784100	0.0%	Put	Sold out−14,400
Novo-Nordisk a SNVO	ADR	670100205	0.0%	Call	Sold out−400,000
Nuvalent Inc	COM	670703107	0.0%		Sold out−23,594
Oruka Therapeutics IncORKA	COM	687604108	0.0%		Sold out−242,021
Palvella Therapeutics Inc NePVLA	COM	697947109	0.0%		Sold out−64,626
Pepgen IncPEPG	COM	713317105	0.0%	Call	Sold out−300,000
Perceptive Cap Solutions Cor	CL A ORD SHS	G70077105	0.0%		Sold out−240,951
Replimune Group IncREPL	COM	76029N106	0.0%	Put	Sold out−300,000
Revolution Medicines IncRVMD	COM	76155X100	0.0%		Sold out−163,142
Revolution Medicines IncRVMD	COM	76155X100	0.0%	Put	Sold out−95,000
Sangamo Therapeutics IncSGMOQ	COM	800677106	0.0%		Sold out−1,218,671
Shuttle Pharmactcls Holdings in	COM	825693401	0.0%		Sold out−68,993
Soleno Therapeutics Inc	COM	834203309	0.0%		Sold out−344,123
Surrozen IncSRZN	COM NEW	86889P208	0.0%		Sold out−173,107
Terns Pharmaceuticals Inc	COM	880881107	0.0%	Put	Sold out−1,200,000
Terns Pharmaceuticals Inc	COM	880881107	0.0%		Sold out−1,456,378
Uniqure NV	SHS	N90064101	0.0%		Sold out−91,060
Veru IncVERU	COM NEW	92536C202	0.0%		Sold out−133,517
VIR Biotechnology IncVIR	COM	92764N102	0.0%		Sold out−293,258

Source: SEC EDGAR, Form 13F-HR, accession 0001420506-26-001820 (on sec.gov). Last ingested by Listed: Oct 22, 2026, 05:26 ET. Listed shows no prices and gives no investment advice.