SILVERARC CAPITAL MANAGEMENT, LLC

Name: SILVERARC CAPITAL MANAGEMENT, LLC: Form 13F holdings for the quarter ended 2026-06-30
Creator: Listed

An institutional investment manager in BOSTON, MA. Its Form 13F for the quarter ended Jun 30, 2026, filed Aug 13, 2026. SEC CIK 1816307.

Share this page

Link

Story card, 1080 × 1920

Reported value$962.2m
Positions73

Holdings: 73 positions

The filing on sec.gov

As filed, largest first. Reported value is what the manager stated for each position at the quarter end, in US dollars; it is filing data, not a price. Weight is the position's share of the total reported value. Changes compare with the 13F for the quarter ended 2026-03-31.

SILVERARC CAPITAL MANAGEMENT, LLC, holdings
Issuer	Class	CUSIP	Reported value$m	Weight	Shares	Put or call	Change on the quarter before
Ascendis Pharma A/S	ORD SHS	K08588103	55.0	5.7%	206,234		New+206,234
Celcuity IncCELC	COM	15102K100	52.4	5.4%	500,996		Added+143,093
Cogent Biosciences IncCOGT	COM	19240Q201	49.6	5.2%	1,280,707		Reduced−33,482
Urogen Pharma Ltd	COM	M96088105	47.9	5.0%	1,301,979		Reduced−201,066
Immunome IncIMNM	COM	45257U108	42.7	4.4%	2,017,009		Added+166,731
Dianthus Therapeutics IncDNTH	COM	252828108	38.0	4.0%	390,000		Reduced−264,746
Rhythm Pharmaceuticals IncRYTM	COM	76243J105	34.6	3.6%	311,461		Added+5,461
Oruka Therapeutics IncORKA	COM	687604108	33.6	3.5%	352,802		Added+201,894
Monte Rosa Therapeutics IncGLUE	COM	61225M102	26.8	2.8%	1,108,295		Reduced−893,745
Syndax Pharmaceuticals IncSNDX	COM	87164F105	26.5	2.8%	1,214,390		Added+325,403
Enliven Therapeutics IncELVN	COM	29337E102	24.8	2.6%	489,382		New+489,382
Immunovant IncIMVT	COM	45258J102	23.9	2.5%	619,096		Added+204,860
Erasca IncERAS	COM	29479A108	23.1	2.4%	1,263,026		Reduced−588,786
Sagimet Biosciences IncSGMT	COM SER A	786700104	22.6	2.4%	2,927,698		New+2,927,698
Abivax SAABVX	SPONSORED ADS	00370M103	22.6	2.3%	169,593		Reduced−132,937
Praxis Precision Medicines IPRAX	COM NEW	74006W207	22.0	2.3%	65,679		Reduced−5,873
Kodiak Sciences IncKOD	COM	50015M109	21.3	2.2%	546,256		Reduced−445,674
Ark ETF TR	PUT	00214Q952	21.0	2.2%	500,000	Put	New+500,000
Definium Therapeutics IncDFTX	COM SHS	24477V105	18.8	2.0%	400,000		New+400,000
Veracyte IncVCYT	COM	92337F107	18.7	1.9%	318,001		Added+138,301
Syndax Pharmaceuticals Inc	CALL	87164F905	15.2	1.6%	693,600	Call	Added+373,600
Guardant Health IncGH	COM	40131M109	15.0	1.6%	99,826		Added+1,312
C4 Therapeutics IncCCCC	COM STK	12529R107	14.2	1.5%	3,032,060		Added+1,120,275
Zenas Biopharma IncZBIO	COM	98937L105	12.9	1.3%	509,789		Reduced−626,146
Trevi Therapeutics IncTRVI	COM	89532M101	12.6	1.3%	678,095		Added+166,968
Helix Acquisition Corp III	USD CL A ORD SHS	G4444S107	12.5	1.3%	1,177,821		Reduced−31,165
ALX Oncology Holdings IncALXO	COM	00166B105	11.9	1.2%	5,744,757		New+5,744,757
Veradermics IncMANE	COMMON STOCK	922967104	11.7	1.2%	95,000		New+95,000
Xenon Pharmaceuticals IncXENE	COM	98420N105	11.3	1.2%	186,821		Reduced−10,938
Avalyn Pharmaceuticals IncAVLN	COM SHS	05348Y105	10.9	1.1%	330,487		New+330,487
Biogen IncBIIB	COM	09062X103	10.4	1.1%	48,101		Reduced−2,866
Aclaris Therapeutics IncACRS	COM	00461U105	10.3	1.1%	1,946,482		New+1,946,482
Cerus CorpCERS	COM	157085101	10.1	1.1%	3,472,737		Added+296,190
Avalo Therapeutics IncAVTX	COM NEW	05338F306	9.2	1.0%	500,402		New+500,402
Benitec Biopharma IncBNTC	COM NEW	08205P209	9.1	0.9%	679,826		Reduced−37,899
Vaxcyte IncPCVX	COM	92243G108	8.4	0.9%	145,000		Added+19
Genedx Holdings CorpWGS	COM CL A	81663L200	8.4	0.9%	122,269		New+122,269
Savara IncSVRA	COM	805111101	8.3	0.9%	1,355,459		Reduced−75,523
Ovid Therapeutics IncOVID	COM	690469101	8.3	0.9%	3,101,129		Added+2,101,129
Oric Pharmaceuticals IncORIC	COM	68622P109	8.0	0.8%	738,873		Reduced−361,137
Oric Pharmaceuticals Inc	CALL	68622P909	7.4	0.8%	682,600	Call	New+682,600
Monte Rosa Therapeutics Inc	CALL	61225M902	7.3	0.8%	300,000	Call	New+300,000
Compass Pathways plcCMPS	SPONSORED ADS	20451W101	7.1	0.7%	503,382		Added+203,382
Compugen Ltd	ORD	M25722105	6.8	0.7%	3,184,257		Reduced−131,588
Solid Biosciences IncSLDB	COM NEW	83422E204	6.7	0.7%	668,450		New+668,450
Abivax SA	CALL	00370M903	6.7	0.7%	50,000	Call	New+50,000
Ibio IncIBIO	COM NEW	451033708	6.2	0.6%	3,520,490		Added+3,294,490
Disc Medicine IncIRON	COM	254604101	6.1	0.6%	82,800		Reduced−113,228
Alkermes plc	SHS	G01767105	5.9	0.6%	113,494		Reduced−346,820
Spyre Therapeutics IncSYRE	COM NEW	00773J202	5.3	0.6%	59,959		Reduced−126,659
Artiva Biotherapeutics IncARTV	COM	04317A107	5.1	0.5%	525,000		New+525,000
Contineum Therapeutics IncCTNM	CL A	21217B100	4.9	0.5%	296,135		Reduced−5,594
Uniqure NV	SHS	N90064101	4.8	0.5%	105,000		New+105,000
Research Alliance Corp III	ORD SHS CL A	G75226103	3.9	0.4%	360,000		New+360,000
Abeona Therapeutics IncABEO	COM NEW	00289Y206	3.8	0.4%	610,407		Reduced−38,535
Insmed IncINSM	COM PAR $.01	457669307	3.7	0.4%	34,438		Reduced−1,412
Karyopharm Therapeutics IncKPTI	COM NEW	48576U205	2.9	0.3%	297,460		New+297,460
Kymera Therapeutics Inc	PUT	501575954	2.9	0.3%	25,000	Put	New+25,000
CAMP4 Therapeutics CorpCAMP	COM	13463J101	2.9	0.3%	653,594		Unchanged
Elutia IncELUT	CL A COM	05479K106	2.1	0.2%	2,192,980		Reduced−305,040
Revolution Medicines IncRVMD	COM	76155X100	1.9	0.2%	10,000		New+10,000
Sionna Therapeutics IncSION	COM	829401108	1.9	0.2%	42,478		Added+3,061
Absci Corporation	PUT	00091E959	1.8	0.2%	157,600	Put	New+157,600
Tela Bio IncTELA	COM	872381108	1.6	0.2%	2,137,201		Reduced−122,111
Achieve Life Science IncACHV	COM	004468500	1.5	0.2%	227,178		New+227,178
Fulcrum Therapeutics Inc	CALL	359616909	1.4	0.1%	391,900	Call	Unchanged
Fractyl Health Inc	COM	35168W103	1.3	0.1%	1,637,976		Reduced−63,649
Connect Biopharma Holdings Ltd	SHS	G23549101	1.3	0.1%	545,000		New+545,000
Crescent Biopharma Inc.	COM	G2545C104	1.1	0.1%	59,104		Reduced−71,396
Cellectar Biosciences IncCLRB	COM NEW	15117F880	0.9	<0.1%	321,728		New+321,728
Foghorn Therapeutics IncFHTX	COM	344174107	0.2	<0.1%	45,975		New+45,975
Adagio Med Holdings IncADGM	COM	00534B100	0.1	<0.1%	224,360		Reduced−27,612
Rocket Pharmaceuticals Inc	*W EXP 09/02/202	77313F114	0.0	<0.1%	104,828		Unchanged

Sold out: 26 positions

Held at the end of the quarter before and not reported this quarter.

SILVERARC CAPITAL MANAGEMENT, LLC, positions sold out
Issuer	Class	CUSIP	Weight	Put or call	Change on the quarter before
Aardvark Therapeutics IncAARD	COM	002942100	0.0%		Sold out−33,684
Annexon IncANNX	COM	03589W102	0.0%		Sold out−496,461
Ascendis Pharma A/S	SPONSORED ADR	04351P101	0.0%		Sold out−124,658
Celcuity Inc	CALL	15102K900	0.0%	Call	Sold out−54,500
Celldex Therapeutics Inc NewCLDX	COM NEW	15117B202	0.0%		Sold out−178,378
Centessa Pharmaceuticals plc	SPONSORED ADS	152309100	0.0%		Sold out−466,345
CG Oncology IncCGON	COM	156944100	0.0%		Sold out−166,349
Climb Bio IncCLYM	COM	28658R106	0.0%		Sold out−684,908
Compass Therapeutics Inc	CALL	20454B904	0.0%	Call	Sold out−172,400
Compass Therapeutics IncCMPX	COM	20454B104	0.0%		Sold out−859,049
Cytokinetics IncCYTK	COM NEW	23282W605	0.0%		Sold out−71,203
Edgewise Therapeutics IncEWTX	COM	28036F105	0.0%		Sold out−42,615
Fulcrum Therapeutics IncFULC	COM	359616109	0.0%		Sold out−419,949
Generate Biomedicines IncGENB	COM SHS	370920100	0.0%		Sold out−100,000
Kalvista Pharmaceuticals Inc	COM	483497103	0.0%		Sold out−2,876,407
Monopar Therapeutics IncMNPR	COM NEW	61023L207	0.0%		Sold out−43,488
Neumora Therapeutics Inc.NMRA	COM	640979100	0.0%		Sold out−818,156
Nextcure IncNXTC	COM NEW	65343E207	0.0%		Sold out−176,057
Nuvalent Inc	COM	670703107	0.0%		Sold out−354,914
Radiopharm Theranostics LtdRADX	SPONSORED ADS	75041J101	0.0%		Sold out−187,406
Replimune Group IncREPL	COM	76029N106	0.0%		Sold out−171,936
Scholar Rock HLDG CorpSRRK	COM	80706P103	0.0%		Sold out−339,613
SPDR Series Trust	PUT	78464A950	0.0%	Put	Sold out−825,000
Surrozen IncSRZN	COM NEW	86889P208	0.0%		Sold out−144,255
Uniqure NV	CALL	N90064901	0.0%	Call	Sold out−500,000
Zura Bio Ltd	CLASS A ORD SHS	G9TY5A101	0.0%		Sold out−560,651

Source: SEC EDGAR, Form 13F-HR, accession 0001420506-26-001563 (on sec.gov). Last ingested by Listed: Oct 22, 2026, 05:26 ET. Listed shows no prices and gives no investment advice.