Listed

Alnylam Pharmaceuticals, Inc.

ALNYNasdaqCIK 1178670HealthcareFiscal year ends Dec 31

Latest reported revenue, Q3 FY2026$1.46bnRevenue, Q3 FY2026, three months to 2026-09-30$1.46bn. XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. 10-Q filed 2026-10-29, accession 0001178670-26-000076.Report this figureThree months to Sep 30, 2026, from the 10-Q filed Oct 29, 2026.

Latest quarter: Q3 FY2026

Three months to Sep 30, 2026, against the same quarter a year earlier.

  • Revenue$1.46bnRevenue, Q3 FY2026, three months to 2026-09-30$1.46bn. XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. 10-Q filed 2026-10-29, accession 0001178670-26-000076.Report this figure+16.7% on a year earlier
  • Gross marginnot reported (Gross profit not reported)No year-earlier figure to compare
  • Operating margin23.7%Operating margin, Q3 FY2026, three months to 2026-09-30. operating income / revenueOperating income: $345.8m. XBRL concept us-gaap:OperatingIncomeLoss. 10-Q filed 2026-10-29, accession 0001178670-26-000076.Revenue: $1.46bn. XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. 10-Q filed 2026-10-29, accession 0001178670-26-000076.Report this figure−5.7 pts on a year earlier
  • Net margin148.6%Net margin, Q3 FY2026, three months to 2026-09-30. net income / revenueNet income: $2.17bn. XBRL concept us-gaap:NetIncomeLoss. 10-Q filed 2026-10-29, accession 0001178670-26-000076.Revenue: $1.46bn. XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. 10-Q filed 2026-10-29, accession 0001178670-26-000076.Report this figure+125.2 pts on a year earlier
  • Diluted EPS$15.72Diluted EPS, Q3 FY2026, three months to 2026-09-30$15.72 per share. XBRL concept us-gaap:EarningsPerShareDiluted. 10-Q filed 2026-10-29, accession 0001178670-26-000076.Report this figure+634.6% on a year earlier
  • Free cash flow$271.2mFree cash flow, Q3 FY2026, three months to 2026-09-30. operating cash flow − capital expenditureOperating cash flow: $341.0m. XBRL concept us-gaap:NetCashProvidedByUsedInOperatingActivities. 10-Q filed 2026-10-29, accession 0001178670-26-000076. Derived: 9-month figure less the 6-month figure.Capital expenditure: $69.8m. XBRL concept us-gaap:PaymentsToAcquirePropertyPlantAndEquipment. 10-Q filed 2026-10-29, accession 0001178670-26-000076. Derived: 9-month figure less the 6-month figure.Report this figure−4.8% on a year earlier

Last eight quarters

Full statements
Revenue$1.46bnOperating margin 23.7%
Diluted EPS$15.72, Q3 FY2026
Free cash flow$271.2m, Q3 FY2026
Alnylam Pharmaceuticals, Inc., key figures for the last eight quarters
Line itemUnitQ4 FY20242024-12-31Q1 FY20252025-03-31Q2 FY20252025-06-30Q3 FY20252025-09-30Q4 FY20252025-12-31period not labelled2026-03-31Q2 FY20262026-06-30Q3 FY20262026-09-30Shape over the periods
Revenue$m593Revenue, Q4 FY2024, three months to 2024-12-31$593.2m. XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. 10-K filed 2026-02-12, accession 0001628280-26-007497. Derived: 12-month figure less the 9-month figure.Report this figure594Revenue, Q1 FY2025, three months to 2025-03-31$594.2m. XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. 10-Q filed 2025-05-01, accession 0001178670-25-000052.Report this figure774Revenue, Q2 FY2025, three months to 2025-06-30$773.7m. XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. 10-Q filed 2026-07-30, accession 0001178670-26-000062.Report this figure1,249Revenue, Q3 FY2025, three months to 2025-09-30$1.25bn. XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. 10-Q filed 2026-10-29, accession 0001178670-26-000076.Report this figure1,097Revenue, Q4 FY2025, three months to 2025-12-31$1.10bn. XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. 10-K filed 2026-02-12, accession 0001628280-26-007497. Derived: 12-month figure less the 9-month figure.Report this figurenot reported (Revenue not reported)1,291Revenue, Q2 FY2026, three months to 2026-06-30$1.29bn. XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. 10-Q filed 2026-07-30, accession 0001178670-26-000062.Report this figure1,458Revenue, Q3 FY2026, three months to 2026-09-30$1.46bn. XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. 10-Q filed 2026-10-29, accession 0001178670-26-000076.Report this figure
Gross margin%not reported (Gross profit not reported)not reported (Gross profit not reported)not reported (Gross profit not reported)not reported (Gross profit not reported)not reported (Gross profit not reported)not reported (Gross profit and Revenue not reported)not reported (Gross profit not reported)not reported (Gross profit not reported)
Operating margin%(17.7%)Operating margin, Q4 FY2024, three months to 2024-12-31. operating income / revenueOperating income: −$105.2m. XBRL concept us-gaap:OperatingIncomeLoss. 10-K filed 2026-02-12, accession 0001628280-26-007497. Derived: 12-month figure less the 9-month figure.Revenue: $593.2m. XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. 10-K filed 2026-02-12, accession 0001628280-26-007497. Derived: 12-month figure less the 9-month figure.Report this figure3.0%Operating margin, Q1 FY2025, three months to 2025-03-31. operating income / revenueOperating income: $18.1m. XBRL concept us-gaap:OperatingIncomeLoss. 10-Q filed 2025-05-01, accession 0001178670-25-000052.Revenue: $594.2m. XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. 10-Q filed 2025-05-01, accession 0001178670-25-000052.Report this figure(2.1%)Operating margin, Q2 FY2025, three months to 2025-06-30. operating income / revenueOperating income: −$16.2m. XBRL concept us-gaap:OperatingIncomeLoss. 10-Q filed 2026-07-30, accession 0001178670-26-000062.Revenue: $773.7m. XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. 10-Q filed 2026-07-30, accession 0001178670-26-000062.Report this figure29.5%Operating margin, Q3 FY2025, three months to 2025-09-30. operating income / revenueOperating income: $368.0m. XBRL concept us-gaap:OperatingIncomeLoss. 10-Q filed 2026-10-29, accession 0001178670-26-000076.Revenue: $1.25bn. XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. 10-Q filed 2026-10-29, accession 0001178670-26-000076.Report this figure12.0%Operating margin, Q4 FY2025, three months to 2025-12-31. operating income / revenueOperating income: $131.7m. XBRL concept us-gaap:OperatingIncomeLoss. 10-K filed 2026-02-12, accession 0001628280-26-007497. Derived: 12-month figure less the 9-month figure.Revenue: $1.10bn. XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. 10-K filed 2026-02-12, accession 0001628280-26-007497. Derived: 12-month figure less the 9-month figure.Report this figurenot reported (Operating income and Revenue not reported)17.9%Operating margin, Q2 FY2026, three months to 2026-06-30. operating income / revenueOperating income: $231.4m. XBRL concept us-gaap:OperatingIncomeLoss. 10-Q filed 2026-07-30, accession 0001178670-26-000062.Revenue: $1.29bn. XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. 10-Q filed 2026-07-30, accession 0001178670-26-000062.Report this figure23.7%Operating margin, Q3 FY2026, three months to 2026-09-30. operating income / revenueOperating income: $345.8m. XBRL concept us-gaap:OperatingIncomeLoss. 10-Q filed 2026-10-29, accession 0001178670-26-000076.Revenue: $1.46bn. XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. 10-Q filed 2026-10-29, accession 0001178670-26-000076.Report this figure
Net margin%(14.1%)Net margin, Q4 FY2024, three months to 2024-12-31. net income / revenueNet income: −$83.8m. XBRL concept us-gaap:NetIncomeLoss. 10-K filed 2026-02-12, accession 0001628280-26-007497. Derived: 12-month figure less the 9-month figure.Revenue: $593.2m. XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. 10-K filed 2026-02-12, accession 0001628280-26-007497. Derived: 12-month figure less the 9-month figure.Report this figure(3.1%)Net margin, Q1 FY2025, three months to 2025-03-31. net income / revenueNet income: −$18.3m. XBRL concept us-gaap:NetIncomeLoss. 10-Q filed 2026-10-29, accession 0001178670-26-000076.Revenue: $594.2m. XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. 10-Q filed 2025-05-01, accession 0001178670-25-000052.Report this figure(9.3%)Net margin, Q2 FY2025, three months to 2025-06-30. net income / revenueNet income: −$72.2m. XBRL concept us-gaap:NetIncomeLoss. 10-Q filed 2026-10-29, accession 0001178670-26-000076.Revenue: $773.7m. XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. 10-Q filed 2026-07-30, accession 0001178670-26-000062.Report this figure23.4%Net margin, Q3 FY2025, three months to 2025-09-30. net income / revenueNet income: $292.7m. XBRL concept us-gaap:NetIncomeLoss. 10-Q filed 2026-10-29, accession 0001178670-26-000076.Revenue: $1.25bn. XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. 10-Q filed 2026-10-29, accession 0001178670-26-000076.Report this figure10.2%Net margin, Q4 FY2025, three months to 2025-12-31. net income / revenueNet income: $111.5m. XBRL concept us-gaap:NetIncomeLoss. 10-K filed 2026-02-12, accession 0001628280-26-007497. Derived: 12-month figure less the 9-month figure.Revenue: $1.10bn. XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. 10-K filed 2026-02-12, accession 0001628280-26-007497. Derived: 12-month figure less the 9-month figure.Report this figurenot reported (Revenue not reported)12.7%Net margin, Q2 FY2026, three months to 2026-06-30. net income / revenueNet income: $164.5m. XBRL concept us-gaap:NetIncomeLoss. 10-Q filed 2026-10-29, accession 0001178670-26-000076.Revenue: $1.29bn. XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. 10-Q filed 2026-07-30, accession 0001178670-26-000062.Report this figure148.6%Net margin, Q3 FY2026, three months to 2026-09-30. net income / revenueNet income: $2.17bn. XBRL concept us-gaap:NetIncomeLoss. 10-Q filed 2026-10-29, accession 0001178670-26-000076.Revenue: $1.46bn. XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. 10-Q filed 2026-10-29, accession 0001178670-26-000076.Report this figure
Diluted EPS$ per sharenot reported (Diluted EPS not reported)(0.14)Diluted EPS, Q1 FY2025, three months to 2025-03-31−$0.14 per share. XBRL concept us-gaap:EarningsPerShareDiluted. 10-K filed 2026-02-12, accession 0001628280-26-007497.Report this figure(0.55)Diluted EPS, Q2 FY2025, three months to 2025-06-30−$0.55 per share. XBRL concept us-gaap:EarningsPerShareDiluted. 10-Q filed 2026-07-30, accession 0001178670-26-000062.Report this figure2.14Diluted EPS, Q3 FY2025, three months to 2025-09-30$2.14 per share. XBRL concept us-gaap:EarningsPerShareDiluted. 10-Q filed 2026-10-29, accession 0001178670-26-000076.Report this figurenot reported (Diluted EPS not reported)not reported (Diluted EPS not reported)1.21Diluted EPS, Q2 FY2026, three months to 2026-06-30$1.21 per share. XBRL concept us-gaap:EarningsPerShareDiluted. 10-Q filed 2026-07-30, accession 0001178670-26-000062.Report this figure15.72Diluted EPS, Q3 FY2026, three months to 2026-09-30$15.72 per share. XBRL concept us-gaap:EarningsPerShareDiluted. 10-Q filed 2026-10-29, accession 0001178670-26-000076.Report this figure
Free cash flow$m(104)Free cash flow, Q4 FY2024, three months to 2024-12-31. operating cash flow − capital expenditureOperating cash flow: −$94.7m. XBRL concept us-gaap:NetCashProvidedByUsedInOperatingActivities. 10-K filed 2026-02-12, accession 0001628280-26-007497. Derived: 12-month figure less the 9-month figure.Capital expenditure: $9.1m. XBRL concept us-gaap:PaymentsToAcquirePropertyPlantAndEquipment. 10-K filed 2026-02-12, accession 0001628280-26-007497. Derived: 12-month figure less the 9-month figure.Report this figure(127)Free cash flow, Q1 FY2025, three months to 2025-03-31. operating cash flow − capital expenditureOperating cash flow: −$118.3m. XBRL concept us-gaap:NetCashProvidedByUsedInOperatingActivities. 10-Q filed 2025-05-01, accession 0001178670-25-000052.Capital expenditure: $9.0m. XBRL concept us-gaap:PaymentsToAcquirePropertyPlantAndEquipment. 10-Q filed 2025-05-01, accession 0001178670-25-000052.Report this figure114Free cash flow, Q2 FY2025, three months to 2025-06-30. operating cash flow − capital expenditureOperating cash flow: $127.8m. XBRL concept us-gaap:NetCashProvidedByUsedInOperatingActivities. 10-Q filed 2026-07-30, accession 0001178670-26-000062. Derived: 6-month figure less the 3-month figure.Capital expenditure: $14.3m. XBRL concept us-gaap:PaymentsToAcquirePropertyPlantAndEquipment. 10-Q filed 2026-07-30, accession 0001178670-26-000062. Derived: 6-month figure less the 3-month figure.Report this figure285Free cash flow, Q3 FY2025, three months to 2025-09-30. operating cash flow − capital expenditureOperating cash flow: $296.9m. XBRL concept us-gaap:NetCashProvidedByUsedInOperatingActivities. 10-Q filed 2026-10-29, accession 0001178670-26-000076. Derived: 9-month figure less the 6-month figure.Capital expenditure: $12.1m. XBRL concept us-gaap:PaymentsToAcquirePropertyPlantAndEquipment. 10-Q filed 2026-10-29, accession 0001178670-26-000076. Derived: 9-month figure less the 6-month figure.Report this figure194Free cash flow, Q4 FY2025, three months to 2025-12-31. operating cash flow − capital expenditureOperating cash flow: $217.7m. XBRL concept us-gaap:NetCashProvidedByUsedInOperatingActivities. 10-K filed 2026-02-12, accession 0001628280-26-007497. Derived: 12-month figure less the 9-month figure.Capital expenditure: $23.3m. XBRL concept us-gaap:PaymentsToAcquirePropertyPlantAndEquipment. 10-K filed 2026-02-12, accession 0001628280-26-007497. Derived: 12-month figure less the 9-month figure.Report this figurenot reported (Operating cash flow and Capital expenditure not reported)not reported (Operating cash flow and Capital expenditure not reported)271Free cash flow, Q3 FY2026, three months to 2026-09-30. operating cash flow − capital expenditureOperating cash flow: $341.0m. XBRL concept us-gaap:NetCashProvidedByUsedInOperatingActivities. 10-Q filed 2026-10-29, accession 0001178670-26-000076. Derived: 9-month figure less the 6-month figure.Capital expenditure: $69.8m. XBRL concept us-gaap:PaymentsToAcquirePropertyPlantAndEquipment. 10-Q filed 2026-10-29, accession 0001178670-26-000076. Derived: 9-month figure less the 6-month figure.Report this figure

Focus or hover a figure to see its XBRL concept, period and filing; each links to that filing. A figure marked d is derived: a quarter computed from year-to-date figures, such as the fourth quarter as the fiscal year less the nine months before it. A ratio reads not reported when any input is missing.

Last five fiscal years

Revenue$3.71bnOperating margin 13.5%
Diluted EPS$2.33, FY2025
Free cash flow$465.4m, FY2025
Alnylam Pharmaceuticals, Inc., key figures for the last five fiscal years
Line itemUnitFY20212021-12-31FY20222022-12-31FY20232023-12-31FY20242024-12-31FY20252025-12-31Shape over the periods
Revenue$m844Revenue, FY2021, twelve months to 2021-12-31$844.3m. XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. 10-K filed 2024-02-15, accession 0001178670-24-000008.Report this figure1,037Revenue, FY2022, twelve months to 2022-12-31$1.04bn. XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. 10-K filed 2025-02-13, accession 0001178670-25-000026.Report this figure1,828Revenue, FY2023, twelve months to 2023-12-31$1.83bn. XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. 10-K filed 2026-02-12, accession 0001628280-26-007497.Report this figure2,248Revenue, FY2024, twelve months to 2024-12-31$2.25bn. XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. 10-K filed 2026-02-12, accession 0001628280-26-007497.Report this figure3,714Revenue, FY2025, twelve months to 2025-12-31$3.71bn. XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. 10-K filed 2026-02-12, accession 0001628280-26-007497.Report this figure
Gross margin%not reported (Gross profit not reported)not reported (Gross profit not reported)not reported (Gross profit not reported)not reported (Gross profit not reported)not reported (Gross profit not reported)
Operating margin%(83.9%)Operating margin, FY2021, twelve months to 2021-12-31. operating income / revenueOperating income: −$708.7m. XBRL concept us-gaap:OperatingIncomeLoss. 10-K filed 2024-02-15, accession 0001178670-24-000008.Revenue: $844.3m. XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. 10-K filed 2024-02-15, accession 0001178670-24-000008.Report this figure(75.7%)Operating margin, FY2022, twelve months to 2022-12-31. operating income / revenueOperating income: −$785.1m. XBRL concept us-gaap:OperatingIncomeLoss. 10-K filed 2025-02-13, accession 0001178670-25-000026.Revenue: $1.04bn. XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. 10-K filed 2025-02-13, accession 0001178670-25-000026.Report this figure(15.4%)Operating margin, FY2023, twelve months to 2023-12-31. operating income / revenueOperating income: −$282.2m. XBRL concept us-gaap:OperatingIncomeLoss. 10-K filed 2026-02-12, accession 0001628280-26-007497.Revenue: $1.83bn. XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. 10-K filed 2026-02-12, accession 0001628280-26-007497.Report this figure(7.9%)Operating margin, FY2024, twelve months to 2024-12-31. operating income / revenueOperating income: −$176.9m. XBRL concept us-gaap:OperatingIncomeLoss. 10-K filed 2026-02-12, accession 0001628280-26-007497.Revenue: $2.25bn. XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. 10-K filed 2026-02-12, accession 0001628280-26-007497.Report this figure13.5%Operating margin, FY2025, twelve months to 2025-12-31. operating income / revenueOperating income: $501.6m. XBRL concept us-gaap:OperatingIncomeLoss. 10-K filed 2026-02-12, accession 0001628280-26-007497.Revenue: $3.71bn. XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. 10-K filed 2026-02-12, accession 0001628280-26-007497.Report this figure
Net margin%(101.0%)Net margin, FY2021, twelve months to 2021-12-31. net income / revenueNet income: −$852.8m. XBRL concept us-gaap:NetIncomeLoss. 10-K filed 2024-02-15, accession 0001178670-24-000008.Revenue: $844.3m. XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. 10-K filed 2024-02-15, accession 0001178670-24-000008.Report this figure(109.0%)Net margin, FY2022, twelve months to 2022-12-31. net income / revenueNet income: −$1.13bn. XBRL concept us-gaap:NetIncomeLoss. 10-K filed 2025-02-13, accession 0001178670-25-000026.Revenue: $1.04bn. XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. 10-K filed 2025-02-13, accession 0001178670-25-000026.Report this figure(24.1%)Net margin, FY2023, twelve months to 2023-12-31. net income / revenueNet income: −$440.2m. XBRL concept us-gaap:NetIncomeLoss. 10-K filed 2026-02-12, accession 0001628280-26-007497.Revenue: $1.83bn. XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. 10-K filed 2026-02-12, accession 0001628280-26-007497.Report this figure(12.4%)Net margin, FY2024, twelve months to 2024-12-31. net income / revenueNet income: −$278.2m. XBRL concept us-gaap:NetIncomeLoss. 10-K filed 2026-02-12, accession 0001628280-26-007497.Revenue: $2.25bn. XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. 10-K filed 2026-02-12, accession 0001628280-26-007497.Report this figure8.4%Net margin, FY2025, twelve months to 2025-12-31. net income / revenueNet income: $313.7m. XBRL concept us-gaap:NetIncomeLoss. 10-K filed 2026-02-12, accession 0001628280-26-007497.Revenue: $3.71bn. XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. 10-K filed 2026-02-12, accession 0001628280-26-007497.Report this figure
Diluted EPS$ per share(7.20)Diluted EPS, FY2021, twelve months to 2021-12-31−$7.20 per share. XBRL concept us-gaap:EarningsPerShareDiluted. 10-K filed 2024-02-15, accession 0001178670-24-000008.Report this figure(9.30)Diluted EPS, FY2022, twelve months to 2022-12-31−$9.30 per share. XBRL concept us-gaap:EarningsPerShareDiluted. 10-K filed 2025-02-13, accession 0001178670-25-000026.Report this figure(3.52)Diluted EPS, FY2023, twelve months to 2023-12-31−$3.52 per share. XBRL concept us-gaap:EarningsPerShareDiluted. 10-K filed 2026-02-12, accession 0001628280-26-007497.Report this figure(2.18)Diluted EPS, FY2024, twelve months to 2024-12-31−$2.18 per share. XBRL concept us-gaap:EarningsPerShareDiluted. 10-K filed 2026-02-12, accession 0001628280-26-007497.Report this figure2.33Diluted EPS, FY2025, twelve months to 2025-12-31$2.33 per share. XBRL concept us-gaap:EarningsPerShareDiluted. 10-K filed 2026-02-12, accession 0001628280-26-007497.Report this figure
Free cash flow$m(718)Free cash flow, FY2021, twelve months to 2021-12-31. operating cash flow − capital expenditureOperating cash flow: −$641.7m. XBRL concept us-gaap:NetCashProvidedByUsedInOperatingActivities. 10-K filed 2024-02-15, accession 0001178670-24-000008.Capital expenditure: $76.4m. XBRL concept us-gaap:PaymentsToAcquirePropertyPlantAndEquipment. 10-K filed 2024-02-15, accession 0001178670-24-000008.Report this figure(613)Free cash flow, FY2022, twelve months to 2022-12-31. operating cash flow − capital expenditureOperating cash flow: −$541.3m. XBRL concept us-gaap:NetCashProvidedByUsedInOperatingActivities. 10-K filed 2025-02-13, accession 0001178670-25-000026.Capital expenditure: $72.1m. XBRL concept us-gaap:PaymentsToAcquirePropertyPlantAndEquipment. 10-K filed 2025-02-13, accession 0001178670-25-000026.Report this figure41.9Free cash flow, FY2023, twelve months to 2023-12-31. operating cash flow − capital expenditureOperating cash flow: $104.2m. XBRL concept us-gaap:NetCashProvidedByUsedInOperatingActivities. 10-K filed 2026-02-12, accession 0001628280-26-007497.Capital expenditure: $62.2m. XBRL concept us-gaap:PaymentsToAcquirePropertyPlantAndEquipment. 10-K filed 2026-02-12, accession 0001628280-26-007497.Report this figure(42.6)Free cash flow, FY2024, twelve months to 2024-12-31. operating cash flow − capital expenditureOperating cash flow: −$8.3m. XBRL concept us-gaap:NetCashProvidedByUsedInOperatingActivities. 10-K filed 2026-02-12, accession 0001628280-26-007497.Capital expenditure: $34.3m. XBRL concept us-gaap:PaymentsToAcquirePropertyPlantAndEquipment. 10-K filed 2026-02-12, accession 0001628280-26-007497.Report this figure465Free cash flow, FY2025, twelve months to 2025-12-31. operating cash flow − capital expenditureOperating cash flow: $524.1m. XBRL concept us-gaap:NetCashProvidedByUsedInOperatingActivities. 10-K filed 2026-02-12, accession 0001628280-26-007497.Capital expenditure: $58.7m. XBRL concept us-gaap:PaymentsToAcquirePropertyPlantAndEquipment. 10-K filed 2026-02-12, accession 0001628280-26-007497.Report this figure

Focus or hover a figure to see its XBRL concept, period and filing; each links to that filing. A figure marked d is derived: a quarter computed from year-to-date figures, such as the fourth quarter as the fiscal year less the nine months before it. A ratio reads not reported when any input is missing.

Insider purchases and sales

All insider transactions

The last 20 open-market transactions reported on Form 4 (codes P and S). The reported price is the price per share the insider stated on the form: filing data, not a market price.

No open-market purchases or sales by insiders are in coverage from Dec 2024 to Nov 2026.

Alnylam Pharmaceuticals, Inc., open-market insider transactions
DateInsiderTransactionSharesReported priceValueFiling
2017-05-31Sanofi10% owner Purchase297,501$71.87$21.4mForm 4
2016-02-01Sanofi10% owner Purchase205,030$69.75$14.3mForm 4
2015-01-29Sanofi10% owner Purchase97,118$95.00$9.2mForm 4
2015-01-26Sanofi10% owner Purchase647,448$95.00$61.5mForm 4
2015-01-22Sanofi10% owner Purchase196,251$9,317.00$1.83bnForm 4
2015-01-22Sanofi10% owner Purchase196,251$93.17$18.3mForm 4/A

Funds that report holding it

All funds

From each manager's latest Form 13F, largest reported value first. Reported value is as filed at the quarter end: filing data, not a price. A put or call is an option position, not shares held.

Funds that report holding Alnylam Pharmaceuticals, Inc.
FundQuarter endedReported valueSharesPut or callChange on the quarter before
FMR LLC2026-06-30$4.52bn15,023,962Added+444,796
Capital World Investors2026-06-30$3.35bn11,144,846Added+342,498
BlackRock, Inc.2026-06-30$3.28bn10,907,675Added+462,767
Capital Research Global Investors2026-06-30$2.94bn9,750,699Added+279,518
VANGUARD PORTFOLIO MANAGEMENT LLC2026-06-30$1.97bn6,538,390Added+47,110
VANGUARD CAPITAL MANAGEMENT LLC2026-06-30$1.82bn6,029,478Added+82,772
Invesco Ltd.2026-06-30$1.13bn3,754,318Added+2,462,592
STATE STREET CORP2026-06-30$1.07bn3,555,689Added+232,991
GEODE CAPITAL MANAGEMENT, LLC2026-06-30$791.3m2,635,840Reduced−24,545
JPMORGAN CHASE & CO2026-06-30$785.3m2,675,517Reduced−3,648,235

Recent filings

All 1,353 filings

Reports and events: 10-K, 10-Q, 8-K, proxy statements and ownership schedules.

Alnylam Pharmaceuticals, Inc., recent filings
FiledFormWhat it isAccession number
2026-10-2908:20 ET10-QQuarterly reportPeriod 2026-09-300001178670-26-000076
2026-10-2908:16 ET8-K2.02 Results of operations; 9.01 Financial statements and exhibits0001178670-26-000074
2026-07-3008:11 ET10-QQuarterly reportPeriod 2026-06-300001178670-26-000062
2026-07-3008:06 ET8-K2.02 Results of operations; 9.01 Financial statements and exhibits0001178670-26-000060
2026-05-2716:30 ET8-K5.02 Departure or appointment of officers or directors; 5.07 Shareholder vote results0001628280-26-038499
2026-04-3008:16 ET10-QQuarterly reportPeriod 2026-03-310001628280-26-028605
2026-04-3008:04 ET8-K2.02 Results of operations; 9.01 Financial statements and exhibits0001628280-26-028601
2026-04-0616:30 ETDEF 14AProxy statementPeriod 2026-05-200001628280-26-023923
2026-03-0417:17 ET8-K5.02 Departure or appointment of officers or directors0001628280-26-014728
2026-02-1208:12 ET10-KAnnual reportPeriod 2025-12-310001628280-26-007497

Latest annual report

Form 10-K for the fiscal year ended Dec 31, 2025Filed Feb 12, 2026. Its page lists the documents and the extracted sections, such as Business and Risk factors.

Forecast league

Q3 FY2026, the quarter ended 2026-09-30, has been scored from the reported figures.See the target

About the filer

CIK
1178670
Tickers
ALNY
Exchange
Nasdaq
SIC code
2834 Pharmaceutical Preparations
Sector
Healthcare
Fiscal year ends
Dec 31
Incorporated in
not reported
Filer category
Large accelerated filer
Former names
ALNYLAM PHARMACEUTICALS INC (to 2004-07-02)

Source: SEC EDGAR, XBRL company facts, the filing index and Forms 4. Last ingested by Listed: Oct 31, 2026, 15:25 ET. Listed shows no prices and gives no investment advice.