Listed

Ionis Pharmaceuticals Inc

IONSNasdaqCIK 874015HealthcareFiscal year ends Dec 31

Standardized line items from XBRL company facts, the last twelve quarters. Negative values are in parentheses. A figure marked d is derived from year-to-date figures.

Income statement

Revenue$267.9m, Q2 FY2026
Operating income−$102.3m, Q2 FY2026
Net income−$114.6m, Q2 FY2026
Ionis Pharmaceuticals Inc, income statement, quarterly
Line itemUnitQ3 FY20232023-09-30Q4 FY20232023-12-31Q1 FY20242024-03-31Q2 FY20242024-06-30Q3 FY20242024-09-30Q4 FY20242024-12-31Q1 FY20252025-03-31period not labelled2025-06-30Q3 FY20252025-09-30Q4 FY20252025-12-31Q1 FY20262026-03-31Q2 FY20262026-06-30
Revenue$m144Revenue, Q3 FY2023, three months to 2023-09-30$144.2m. XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. 10-Q filed 2024-11-06, accession 0000874015-24-000232.Report this figure325Revenue, Q4 FY2023, three months to 2023-12-31$324.5m. XBRL concept us-gaap:Revenues. 10-K filed 2025-02-19, accession 0000874015-25-000089.Report this figure119Revenue, Q1 FY2024, three months to 2024-03-31$119.5m. XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. 10-Q filed 2025-04-30, accession 0000874015-25-000123.Report this figure225Revenue, Q2 FY2024, three months to 2024-06-30$225.3m. XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. 10-Q filed 2025-07-30, accession 0000874015-25-000167.Report this figure134Revenue, Q3 FY2024, three months to 2024-09-30$133.8m. XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. 10-Q filed 2025-10-29, accession 0000874015-25-000266.Report this figure227Revenue, Q4 FY2024, three months to 2024-12-31$226.6m. XBRL concept us-gaap:Revenues. 10-K filed 2026-02-26, accession 0000874015-26-000115.Report this figure132Revenue, Q1 FY2025, three months to 2025-03-31$131.6m. XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. 10-Q filed 2026-04-29, accession 0000874015-26-000177.Report this figure452Revenue, period not labelled, three months to 2025-06-30$452.0m. XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. 10-Q filed 2026-07-29, accession 0000874015-26-000251.Report this figure157Revenue, Q3 FY2025, three months to 2025-09-30$156.7m. XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. 10-Q filed 2025-10-29, accession 0000874015-25-000266.Report this figure203Revenue, Q4 FY2025, three months to 2025-12-31$203.3m. XBRL concept us-gaap:Revenues. 10-K filed 2026-02-26, accession 0000874015-26-000115.Report this figure246Revenue, Q1 FY2026, three months to 2026-03-31$246.1m. XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. 10-Q filed 2026-04-29, accession 0000874015-26-000177.Report this figure268Revenue, Q2 FY2026, three months to 2026-06-30$267.9m. XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax. 10-Q filed 2026-07-29, accession 0000874015-26-000251.Report this figure
Cost of revenue$m2.2Cost of revenue, Q3 FY2023, three months to 2023-09-30$2.2m. XBRL concept us-gaap:CostOfGoodsAndServicesSold. 10-Q filed 2024-11-06, accession 0000874015-24-000232.Report this figure3.1Cost of revenue, Q4 FY2023, three months to 2023-12-31$3.1m. XBRL concept us-gaap:CostOfGoodsAndServicesSold. 10-K filed 2026-02-26, accession 0000874015-26-000115. Derived: 12-month figure less the 9-month figure.Report this figure2.2Cost of revenue, Q1 FY2024, three months to 2024-03-31$2.2m. XBRL concept us-gaap:CostOfGoodsAndServicesSold. 10-Q filed 2025-04-30, accession 0000874015-25-000123.Report this figure4.2Cost of revenue, Q2 FY2024, three months to 2024-06-30$4.2m. XBRL concept us-gaap:CostOfGoodsAndServicesSold. 10-Q filed 2025-07-30, accession 0000874015-25-000167.Report this figure1.1Cost of revenue, Q3 FY2024, three months to 2024-09-30$1.1m. XBRL concept us-gaap:CostOfGoodsAndServicesSold. 10-Q filed 2025-10-29, accession 0000874015-25-000266.Report this figure3.8Cost of revenue, Q4 FY2024, three months to 2024-12-31$3.8m. XBRL concept us-gaap:CostOfGoodsAndServicesSold. 10-K filed 2026-02-26, accession 0000874015-26-000115. Derived: 12-month figure less the 9-month figure.Report this figure1.5Cost of revenue, Q1 FY2025, three months to 2025-03-31$1.5m. XBRL concept us-gaap:CostOfGoodsAndServicesSold. 10-Q filed 2026-04-29, accession 0000874015-26-000177.Report this figure4.2Cost of revenue, period not labelled, three months to 2025-06-30$4.2m. XBRL concept us-gaap:CostOfGoodsAndServicesSold. 10-Q filed 2026-07-29, accession 0000874015-26-000251.Report this figure2.3Cost of revenue, Q3 FY2025, three months to 2025-09-30$2.3m. XBRL concept us-gaap:CostOfGoodsAndServicesSold. 10-Q filed 2025-10-29, accession 0000874015-25-000266.Report this figure8.0Cost of revenue, Q4 FY2025, three months to 2025-12-31$8.0m. XBRL concept us-gaap:CostOfGoodsAndServicesSold. 10-K filed 2026-02-26, accession 0000874015-26-000115. Derived: 12-month figure less the 9-month figure.Report this figure3.0Cost of revenue, Q1 FY2026, three months to 2026-03-31$3.0m. XBRL concept us-gaap:CostOfGoodsAndServicesSold. 10-Q filed 2026-04-29, accession 0000874015-26-000177.Report this figure2.7Cost of revenue, Q2 FY2026, three months to 2026-06-30$2.7m. XBRL concept us-gaap:CostOfGoodsAndServicesSold. 10-Q filed 2026-07-29, accession 0000874015-26-000251.Report this figure
Research and development$mnot reportednot reportednot reportednot reportednot reportednot reportednot reportednot reportednot reportednot reportednot reportednot reported
Selling, general and administrative$m70.0Selling, general and administrative, Q3 FY2023, three months to 2023-09-30$70.0m. XBRL concept us-gaap:SellingGeneralAndAdministrativeExpense. 10-Q filed 2024-11-06, accession 0000874015-24-000232.Report this figure71.0Selling, general and administrative, Q4 FY2023, three months to 2023-12-31$71.0m. XBRL concept us-gaap:SellingGeneralAndAdministrativeExpense. 10-K filed 2026-02-26, accession 0000874015-26-000115. Derived: 12-month figure less the 9-month figure.Report this figure52.6Selling, general and administrative, Q1 FY2024, three months to 2024-03-31$52.6m. XBRL concept us-gaap:SellingGeneralAndAdministrativeExpense. 10-Q filed 2025-04-30, accession 0000874015-25-000123.Report this figure65.1Selling, general and administrative, Q2 FY2024, three months to 2024-06-30$65.1m. XBRL concept us-gaap:SellingGeneralAndAdministrativeExpense. 10-Q filed 2025-07-30, accession 0000874015-25-000167.Report this figure61.6Selling, general and administrative, Q3 FY2024, three months to 2024-09-30$61.6m. XBRL concept us-gaap:SellingGeneralAndAdministrativeExpense. 10-Q filed 2025-10-29, accession 0000874015-25-000266.Report this figure88.1Selling, general and administrative, Q4 FY2024, three months to 2024-12-31$88.1m. XBRL concept us-gaap:SellingGeneralAndAdministrativeExpense. 10-K filed 2026-02-26, accession 0000874015-26-000115. Derived: 12-month figure less the 9-month figure.Report this figure76.3Selling, general and administrative, Q1 FY2025, three months to 2025-03-31$76.3m. XBRL concept us-gaap:SellingGeneralAndAdministrativeExpense. 10-Q filed 2026-04-29, accession 0000874015-26-000177.Report this figure90.6Selling, general and administrative, period not labelled, three months to 2025-06-30$90.6m. XBRL concept us-gaap:SellingGeneralAndAdministrativeExpense. 10-Q filed 2026-07-29, accession 0000874015-26-000251.Report this figure96.8Selling, general and administrative, Q3 FY2025, three months to 2025-09-30$96.8m. XBRL concept us-gaap:SellingGeneralAndAdministrativeExpense. 10-Q filed 2025-10-29, accession 0000874015-25-000266.Report this figure130Selling, general and administrative, Q4 FY2025, three months to 2025-12-31$130.2m. XBRL concept us-gaap:SellingGeneralAndAdministrativeExpense. 10-K filed 2026-02-26, accession 0000874015-26-000115. Derived: 12-month figure less the 9-month figure.Report this figure150Selling, general and administrative, Q1 FY2026, three months to 2026-03-31$150.4m. XBRL concept us-gaap:SellingGeneralAndAdministrativeExpense. 10-Q filed 2026-04-29, accession 0000874015-26-000177.Report this figure150Selling, general and administrative, Q2 FY2026, three months to 2026-06-30$150.4m. XBRL concept us-gaap:SellingGeneralAndAdministrativeExpense. 10-Q filed 2026-07-29, accession 0000874015-26-000251.Report this figure
Operating income$m(143)Operating income, Q3 FY2023, three months to 2023-09-30−$143.3m. XBRL concept us-gaap:OperatingIncomeLoss. 10-Q filed 2024-11-06, accession 0000874015-24-000232.Report this figure(6.1)Operating income, Q4 FY2023, three months to 2023-12-31−$6.1m. XBRL concept us-gaap:OperatingIncomeLoss. 10-K filed 2025-02-19, accession 0000874015-25-000089.Report this figure(150)Operating income, Q1 FY2024, three months to 2024-03-31−$149.5m. XBRL concept us-gaap:OperatingIncomeLoss. 10-Q filed 2025-04-30, accession 0000874015-25-000123.Report this figure(66.1)Operating income, Q2 FY2024, three months to 2024-06-30−$66.1m. XBRL concept us-gaap:OperatingIncomeLoss. 10-Q filed 2025-07-30, accession 0000874015-25-000167.Report this figure(149)Operating income, Q3 FY2024, three months to 2024-09-30−$148.7m. XBRL concept us-gaap:OperatingIncomeLoss. 10-Q filed 2025-10-29, accession 0000874015-25-000266.Report this figure(111)Operating income, Q4 FY2024, three months to 2024-12-31−$110.8m. XBRL concept us-gaap:OperatingIncomeLoss. 10-K filed 2026-02-26, accession 0000874015-26-000115.Report this figure(147)Operating income, Q1 FY2025, three months to 2025-03-31−$146.9m. XBRL concept us-gaap:OperatingIncomeLoss. 10-Q filed 2026-04-29, accession 0000874015-26-000177.Report this figure140Operating income, period not labelled, three months to 2025-06-30$139.8m. XBRL concept us-gaap:OperatingIncomeLoss. 10-Q filed 2026-07-29, accession 0000874015-26-000251.Report this figure(160)Operating income, Q3 FY2025, three months to 2025-09-30−$160.2m. XBRL concept us-gaap:OperatingIncomeLoss. 10-Q filed 2025-10-29, accession 0000874015-25-000266.Report this figure(214)Operating income, Q4 FY2025, three months to 2025-12-31−$214.5m. XBRL concept us-gaap:OperatingIncomeLoss. 10-K filed 2026-02-26, accession 0000874015-26-000115.Report this figure(117)Operating income, Q1 FY2026, three months to 2026-03-31−$117.4m. XBRL concept us-gaap:OperatingIncomeLoss. 10-Q filed 2026-04-29, accession 0000874015-26-000177.Report this figure(102)Operating income, Q2 FY2026, three months to 2026-06-30−$102.3m. XBRL concept us-gaap:OperatingIncomeLoss. 10-Q filed 2026-07-29, accession 0000874015-26-000251.Report this figure
Interest expense$m4.2Interest expense, Q3 FY2023, three months to 2023-09-30$4.2m. XBRL concept us-gaap:InterestExpense. 10-Q filed 2024-11-06, accession 0000874015-24-000232.Report this figure4.6Interest expense, Q4 FY2023, three months to 2023-12-31$4.6m. XBRL concept us-gaap:InterestExpense. 10-K filed 2026-02-26, accession 0000874015-26-000115. Derived: 12-month figure less the 9-month figure.Report this figure4.2Interest expense, Q1 FY2024, three months to 2024-03-31$4.2m. XBRL concept us-gaap:InterestExpense. 10-Q filed 2025-04-30, accession 0000874015-25-000123.Report this figure4.5Interest expense, Q2 FY2024, three months to 2024-06-30$4.5m. XBRL concept us-gaap:InterestExpense. 10-Q filed 2025-07-30, accession 0000874015-25-000167.Report this figure4.2Interest expense, Q3 FY2024, three months to 2024-09-30$4.2m. XBRL concept us-gaap:InterestExpense. 10-Q filed 2025-10-29, accession 0000874015-25-000266.Report this figure4.2Interest expense, Q4 FY2024, three months to 2024-12-31$4.2m. XBRL concept us-gaap:InterestExpense. 10-K filed 2026-02-26, accession 0000874015-26-000115. Derived: 12-month figure less the 9-month figure.Report this figure4.1Interest expense, Q1 FY2025, three months to 2025-03-31$4.1m. XBRL concept us-gaap:InterestExpense. 10-Q filed 2026-04-29, accession 0000874015-26-000177.Report this figure4.1Interest expense, period not labelled, three months to 2025-06-30$4.1m. XBRL concept us-gaap:InterestExpense. 10-Q filed 2026-07-29, accession 0000874015-26-000251.Report this figure4.2Interest expense, Q3 FY2025, three months to 2025-09-30$4.2m. XBRL concept us-gaap:InterestExpense. 10-Q filed 2025-10-29, accession 0000874015-25-000266.Report this figure4.8Interest expense, Q4 FY2025, three months to 2025-12-31$4.8m. XBRL concept us-gaap:InterestExpense. 10-K filed 2026-02-26, accession 0000874015-26-000115. Derived: 12-month figure less the 9-month figure.Report this figure5.2Interest expense, Q1 FY2026, three months to 2026-03-31$5.2m. XBRL concept us-gaap:InterestExpense. 10-Q filed 2026-04-29, accession 0000874015-26-000177.Report this figure4.6Interest expense, Q2 FY2026, three months to 2026-06-30$4.6m. XBRL concept us-gaap:InterestExpense. 10-Q filed 2026-07-29, accession 0000874015-26-000251.Report this figure
Income tax$m6.6Income tax, Q3 FY2023, three months to 2023-09-30$6.6m. XBRL concept us-gaap:IncomeTaxExpenseBenefit. 10-Q filed 2024-11-06, accession 0000874015-24-000232.Report this figure6.5Income tax, Q4 FY2023, three months to 2023-12-31$6.5m. XBRL concept us-gaap:IncomeTaxExpenseBenefit. 10-K filed 2026-02-26, accession 0000874015-26-000115. Derived: 12-month figure less the 9-month figure.Report this figure0.1Income tax, Q1 FY2024, three months to 2024-03-31$75.0k. XBRL concept us-gaap:IncomeTaxExpenseBenefit. 10-Q filed 2025-04-30, accession 0000874015-25-000123.Report this figure0.1Income tax, Q2 FY2024, three months to 2024-06-30$64.0k. XBRL concept us-gaap:IncomeTaxExpenseBenefit. 10-Q filed 2025-07-30, accession 0000874015-25-000167.Report this figure(3.6)Income tax, Q3 FY2024, three months to 2024-09-30−$3.6m. XBRL concept us-gaap:IncomeTaxExpenseBenefit. 10-Q filed 2025-10-29, accession 0000874015-25-000266.Report this figure(2.7)Income tax, Q4 FY2024, three months to 2024-12-31−$2.7m. XBRL concept us-gaap:IncomeTaxExpenseBenefit. 10-K filed 2026-02-26, accession 0000874015-26-000115. Derived: 12-month figure less the 9-month figure.Report this figure0.1Income tax, Q1 FY2025, three months to 2025-03-31$116.0k. XBRL concept us-gaap:IncomeTaxExpenseBenefit. 10-Q filed 2026-04-29, accession 0000874015-26-000177.Report this figure(0.0)Income tax, period not labelled, three months to 2025-06-30−$20.0k. XBRL concept us-gaap:IncomeTaxExpenseBenefit. 10-Q filed 2026-07-29, accession 0000874015-26-000251.Report this figure0.2Income tax, Q3 FY2025, three months to 2025-09-30$213.0k. XBRL concept us-gaap:IncomeTaxExpenseBenefit. 10-Q filed 2025-10-29, accession 0000874015-25-000266.Report this figure1.5Income tax, Q4 FY2025, three months to 2025-12-31$1.5m. XBRL concept us-gaap:IncomeTaxExpenseBenefit. 10-K filed 2026-02-26, accession 0000874015-26-000115. Derived: 12-month figure less the 9-month figure.Report this figure0.2Income tax, Q1 FY2026, three months to 2026-03-31$218.0k. XBRL concept us-gaap:IncomeTaxExpenseBenefit. 10-Q filed 2026-04-29, accession 0000874015-26-000177.Report this figure1.3Income tax, Q2 FY2026, three months to 2026-06-30$1.3m. XBRL concept us-gaap:IncomeTaxExpenseBenefit. 10-Q filed 2026-07-29, accession 0000874015-26-000251.Report this figure
Net income$m(147)Net income, Q3 FY2023, three months to 2023-09-30−$147.4m. XBRL concept us-gaap:NetIncomeLoss. 10-Q filed 2024-11-06, accession 0000874015-24-000232.Report this figure(9.3)Net income, Q4 FY2023, three months to 2023-12-31−$9.3m. XBRL concept us-gaap:NetIncomeLoss. 10-K filed 2025-02-19, accession 0000874015-25-000089.Report this figure(143)Net income, Q1 FY2024, three months to 2024-03-31−$142.8m. XBRL concept us-gaap:NetIncomeLoss. 10-Q filed 2025-04-30, accession 0000874015-25-000123.Report this figure(66.3)Net income, Q2 FY2024, three months to 2024-06-30−$66.3m. XBRL concept us-gaap:NetIncomeLoss. 10-Q filed 2025-07-30, accession 0000874015-25-000167.Report this figure(140)Net income, Q3 FY2024, three months to 2024-09-30−$140.5m. XBRL concept us-gaap:NetIncomeLoss. 10-Q filed 2025-10-29, accession 0000874015-25-000266.Report this figure(104)Net income, Q4 FY2024, three months to 2024-12-31−$104.3m. XBRL concept us-gaap:NetIncomeLoss. 10-K filed 2026-02-26, accession 0000874015-26-000115.Report this figure(147)Net income, Q1 FY2025, three months to 2025-03-31−$146.9m. XBRL concept us-gaap:NetIncomeLoss. 10-Q filed 2026-04-29, accession 0000874015-26-000177.Report this figure124Net income, period not labelled, three months to 2025-06-30$123.6m. XBRL concept us-gaap:NetIncomeLoss. 10-Q filed 2026-07-29, accession 0000874015-26-000251.Report this figure(129)Net income, Q3 FY2025, three months to 2025-09-30−$128.6m. XBRL concept us-gaap:NetIncomeLoss. 10-Q filed 2025-10-29, accession 0000874015-25-000266.Report this figure(229)Net income, Q4 FY2025, three months to 2025-12-31−$229.4m. XBRL concept us-gaap:NetIncomeLoss. 10-K filed 2026-02-26, accession 0000874015-26-000115.Report this figure(92.5)Net income, Q1 FY2026, three months to 2026-03-31−$92.5m. XBRL concept us-gaap:NetIncomeLoss. 10-Q filed 2026-04-29, accession 0000874015-26-000177.Report this figure(115)Net income, Q2 FY2026, three months to 2026-06-30−$114.6m. XBRL concept us-gaap:NetIncomeLoss. 10-Q filed 2026-07-29, accession 0000874015-26-000251.Report this figure
Diluted EPS$ per share(1.03)Diluted EPS, Q3 FY2023, three months to 2023-09-30−$1.03 per share. XBRL concept us-gaap:EarningsPerShareDiluted. 10-Q filed 2024-11-06, accession 0000874015-24-000232.Report this figure(0.06)Diluted EPS, Q4 FY2023, three months to 2023-12-31−$0.06 per share. XBRL concept us-gaap:EarningsPerShareDiluted. 10-K filed 2025-02-19, accession 0000874015-25-000089.Report this figure(0.98)Diluted EPS, Q1 FY2024, three months to 2024-03-31−$0.98 per share. XBRL concept us-gaap:EarningsPerShareDiluted. 10-Q filed 2025-04-30, accession 0000874015-25-000123.Report this figure(0.45)Diluted EPS, Q2 FY2024, three months to 2024-06-30−$0.45 per share. XBRL concept us-gaap:EarningsPerShareDiluted. 10-Q filed 2025-07-30, accession 0000874015-25-000167.Report this figure(0.95)Diluted EPS, Q3 FY2024, three months to 2024-09-30−$0.95 per share. XBRL concept us-gaap:EarningsPerShareDiluted. 10-Q filed 2025-10-29, accession 0000874015-25-000266.Report this figure(0.66)Diluted EPS, Q4 FY2024, three months to 2024-12-31−$0.66 per share. XBRL concept us-gaap:EarningsPerShareDiluted. 10-K filed 2026-02-26, accession 0000874015-26-000115.Report this figure(0.93)Diluted EPS, Q1 FY2025, three months to 2025-03-31−$0.93 per share. XBRL concept us-gaap:EarningsPerShareDiluted. 10-Q filed 2026-04-29, accession 0000874015-26-000177.Report this figure0.70Diluted EPS, period not labelled, three months to 2025-06-30$0.70 per share. XBRL concept us-gaap:EarningsPerShareDiluted. 10-Q filed 2026-07-29, accession 0000874015-26-000251.Report this figure(0.80)Diluted EPS, Q3 FY2025, three months to 2025-09-30−$0.80 per share. XBRL concept us-gaap:EarningsPerShareDiluted. 10-Q filed 2025-10-29, accession 0000874015-25-000266.Report this figure(1.41)Diluted EPS, Q4 FY2025, three months to 2025-12-31−$1.41 per share. XBRL concept us-gaap:EarningsPerShareDiluted. 10-K filed 2026-02-26, accession 0000874015-26-000115.Report this figure(0.56)Diluted EPS, Q1 FY2026, three months to 2026-03-31−$0.56 per share. XBRL concept us-gaap:EarningsPerShareDiluted. 10-Q filed 2026-04-29, accession 0000874015-26-000177.Report this figure(0.69)Diluted EPS, Q2 FY2026, three months to 2026-06-30−$0.69 per share. XBRL concept us-gaap:EarningsPerShareDiluted. 10-Q filed 2026-07-29, accession 0000874015-26-000251.Report this figure
Basic EPS$ per share(1.03)Basic EPS, Q3 FY2023, three months to 2023-09-30−$1.03 per share. XBRL concept us-gaap:EarningsPerShareBasic. 10-Q filed 2024-11-06, accession 0000874015-24-000232.Report this figure(0.06)Basic EPS, Q4 FY2023, three months to 2023-12-31−$0.06 per share. XBRL concept us-gaap:EarningsPerShareBasic. 10-K filed 2025-02-19, accession 0000874015-25-000089.Report this figure(0.98)Basic EPS, Q1 FY2024, three months to 2024-03-31−$0.98 per share. XBRL concept us-gaap:EarningsPerShareBasic. 10-Q filed 2025-04-30, accession 0000874015-25-000123.Report this figure(0.45)Basic EPS, Q2 FY2024, three months to 2024-06-30−$0.45 per share. XBRL concept us-gaap:EarningsPerShareBasic. 10-Q filed 2025-07-30, accession 0000874015-25-000167.Report this figure(0.95)Basic EPS, Q3 FY2024, three months to 2024-09-30−$0.95 per share. XBRL concept us-gaap:EarningsPerShareBasic. 10-Q filed 2025-10-29, accession 0000874015-25-000266.Report this figure(0.66)Basic EPS, Q4 FY2024, three months to 2024-12-31−$0.66 per share. XBRL concept us-gaap:EarningsPerShareBasic. 10-K filed 2026-02-26, accession 0000874015-26-000115.Report this figure(0.93)Basic EPS, Q1 FY2025, three months to 2025-03-31−$0.93 per share. XBRL concept us-gaap:EarningsPerShareBasic. 10-Q filed 2026-04-29, accession 0000874015-26-000177.Report this figure0.78Basic EPS, period not labelled, three months to 2025-06-30$0.78 per share. XBRL concept us-gaap:EarningsPerShareBasic. 10-Q filed 2026-07-29, accession 0000874015-26-000251.Report this figure(0.80)Basic EPS, Q3 FY2025, three months to 2025-09-30−$0.80 per share. XBRL concept us-gaap:EarningsPerShareBasic. 10-Q filed 2025-10-29, accession 0000874015-25-000266.Report this figure(1.41)Basic EPS, Q4 FY2025, three months to 2025-12-31−$1.41 per share. XBRL concept us-gaap:EarningsPerShareBasic. 10-K filed 2026-02-26, accession 0000874015-26-000115.Report this figure(0.56)Basic EPS, Q1 FY2026, three months to 2026-03-31−$0.56 per share. XBRL concept us-gaap:EarningsPerShareBasic. 10-Q filed 2026-04-29, accession 0000874015-26-000177.Report this figure(0.69)Basic EPS, Q2 FY2026, three months to 2026-06-30−$0.69 per share. XBRL concept us-gaap:EarningsPerShareBasic. 10-Q filed 2026-07-29, accession 0000874015-26-000251.Report this figure

Balance sheet

Cash and equivalents$350.1m, Q2 FY2026
Long-term debt$1.33bn, FY2025
Shareholders' equity$439.7m, Q2 FY2026
Ionis Pharmaceuticals Inc, balance sheet, quarterly
Line itemUnitQ3 FY20232023-09-30FY20232023-12-31Q1 FY20242024-03-31Q2 FY20242024-06-30Q3 FY20242024-09-30FY20242024-12-31Q1 FY20252025-03-31period not labelled2025-06-30Q3 FY20252025-09-30FY20252025-12-31Q1 FY20262026-03-31Q2 FY20262026-06-30
Cash and equivalents$m352Cash and equivalents, Q3 FY2023, at 2023-09-30$352.1m. XBRL concept us-gaap:CashAndCashEquivalentsAtCarryingValue. 10-Q filed 2023-11-02, accession 0000874015-23-000209.Report this figure399Cash and equivalents, FY2023, at 2023-12-31$399.3m. XBRL concept us-gaap:CashAndCashEquivalentsAtCarryingValue. 10-K filed 2025-02-19, accession 0000874015-25-000089.Report this figure349Cash and equivalents, Q1 FY2024, at 2024-03-31$348.9m. XBRL concept us-gaap:CashAndCashEquivalentsAtCarryingValue. 10-Q filed 2024-05-07, accession 0000874015-24-000142.Report this figure294Cash and equivalents, Q2 FY2024, at 2024-06-30$294.0m. XBRL concept us-gaap:CashAndCashEquivalentsAtCarryingValue. 10-Q filed 2024-08-01, accession 0000874015-24-000187.Report this figure335Cash and equivalents, Q3 FY2024, at 2024-09-30$334.6m. XBRL concept us-gaap:CashAndCashEquivalentsAtCarryingValue. 10-Q filed 2024-11-06, accession 0000874015-24-000232.Report this figure242Cash and equivalents, FY2024, at 2024-12-31$242.1m. XBRL concept us-gaap:CashAndCashEquivalentsAtCarryingValue. 10-K filed 2026-02-26, accession 0000874015-26-000115.Report this figure264Cash and equivalents, Q1 FY2025, at 2025-03-31$264.2m. XBRL concept us-gaap:CashAndCashEquivalentsAtCarryingValue. 10-Q filed 2025-04-30, accession 0000874015-25-000123.Report this figure297Cash and equivalents, period not labelled, at 2025-06-30$297.3m. XBRL concept us-gaap:CashAndCashEquivalentsAtCarryingValue. 10-Q filed 2025-07-30, accession 0000874015-25-000167.Report this figure338Cash and equivalents, Q3 FY2025, at 2025-09-30$338.3m. XBRL concept us-gaap:CashAndCashEquivalentsAtCarryingValue. 10-Q filed 2025-10-29, accession 0000874015-25-000266.Report this figure372Cash and equivalents, FY2025, at 2025-12-31$372.3m. XBRL concept us-gaap:CashAndCashEquivalentsAtCarryingValue. 10-Q filed 2026-07-29, accession 0000874015-26-000251.Report this figure173Cash and equivalents, Q1 FY2026, at 2026-03-31$173.4m. XBRL concept us-gaap:CashAndCashEquivalentsAtCarryingValue. 10-Q filed 2026-04-29, accession 0000874015-26-000177.Report this figure350Cash and equivalents, Q2 FY2026, at 2026-06-30$350.1m. XBRL concept us-gaap:CashAndCashEquivalentsAtCarryingValue. 10-Q filed 2026-07-29, accession 0000874015-26-000251.Report this figure
Current assets$m2,585Current assets, Q3 FY2023, at 2023-09-30$2.58bn. XBRL concept us-gaap:AssetsCurrent. 10-Q filed 2023-11-02, accession 0000874015-23-000209.Report this figure2,642Current assets, FY2023, at 2023-12-31$2.64bn. XBRL concept us-gaap:AssetsCurrent. 10-K filed 2025-02-19, accession 0000874015-25-000089.Report this figure2,416Current assets, Q1 FY2024, at 2024-03-31$2.42bn. XBRL concept us-gaap:AssetsCurrent. 10-Q filed 2024-05-07, accession 0000874015-24-000142.Report this figure2,329Current assets, Q2 FY2024, at 2024-06-30$2.33bn. XBRL concept us-gaap:AssetsCurrent. 10-Q filed 2024-08-01, accession 0000874015-24-000187.Report this figure2,714Current assets, Q3 FY2024, at 2024-09-30$2.71bn. XBRL concept us-gaap:AssetsCurrent. 10-Q filed 2024-11-06, accession 0000874015-24-000232.Report this figure2,620Current assets, FY2024, at 2024-12-31$2.62bn. XBRL concept us-gaap:AssetsCurrent. 10-K filed 2026-02-26, accession 0000874015-26-000115.Report this figure2,419Current assets, Q1 FY2025, at 2025-03-31$2.42bn. XBRL concept us-gaap:AssetsCurrent. 10-Q filed 2025-04-30, accession 0000874015-25-000123.Report this figure2,577Current assets, period not labelled, at 2025-06-30$2.58bn. XBRL concept us-gaap:AssetsCurrent. 10-Q filed 2025-07-30, accession 0000874015-25-000167.Report this figure2,519Current assets, Q3 FY2025, at 2025-09-30$2.52bn. XBRL concept us-gaap:AssetsCurrent. 10-Q filed 2025-10-29, accession 0000874015-25-000266.Report this figure2,991Current assets, FY2025, at 2025-12-31$2.99bn. XBRL concept us-gaap:AssetsCurrent. 10-Q filed 2026-07-29, accession 0000874015-26-000251.Report this figure2,937Current assets, Q1 FY2026, at 2026-03-31$2.94bn. XBRL concept us-gaap:AssetsCurrent. 10-Q filed 2026-04-29, accession 0000874015-26-000177.Report this figure2,491Current assets, Q2 FY2026, at 2026-06-30$2.49bn. XBRL concept us-gaap:AssetsCurrent. 10-Q filed 2026-07-29, accession 0000874015-26-000251.Report this figure
Total assets$m2,934Total assets, Q3 FY2023, at 2023-09-30$2.93bn. XBRL concept us-gaap:Assets. 10-Q filed 2023-11-02, accession 0000874015-23-000209.Report this figure2,990Total assets, FY2023, at 2023-12-31$2.99bn. XBRL concept us-gaap:Assets. 10-K filed 2025-02-19, accession 0000874015-25-000089.Report this figure2,764Total assets, Q1 FY2024, at 2024-03-31$2.76bn. XBRL concept us-gaap:Assets. 10-Q filed 2024-05-07, accession 0000874015-24-000142.Report this figure2,691Total assets, Q2 FY2024, at 2024-06-30$2.69bn. XBRL concept us-gaap:Assets. 10-Q filed 2024-08-01, accession 0000874015-24-000187.Report this figure3,081Total assets, Q3 FY2024, at 2024-09-30$3.08bn. XBRL concept us-gaap:Assets. 10-Q filed 2024-11-06, accession 0000874015-24-000232.Report this figure3,004Total assets, FY2024, at 2024-12-31$3.00bn. XBRL concept us-gaap:Assets. 10-K filed 2026-02-26, accession 0000874015-26-000115.Report this figure2,813Total assets, Q1 FY2025, at 2025-03-31$2.81bn. XBRL concept us-gaap:Assets. 10-Q filed 2025-04-30, accession 0000874015-25-000123.Report this figure2,985Total assets, period not labelled, at 2025-06-30$2.99bn. XBRL concept us-gaap:Assets. 10-Q filed 2025-07-30, accession 0000874015-25-000167.Report this figure3,033Total assets, Q3 FY2025, at 2025-09-30$3.03bn. XBRL concept us-gaap:Assets. 10-Q filed 2025-10-29, accession 0000874015-25-000266.Report this figure3,524Total assets, FY2025, at 2025-12-31$3.52bn. XBRL concept us-gaap:Assets. 10-Q filed 2026-07-29, accession 0000874015-26-000251.Report this figure3,450Total assets, Q1 FY2026, at 2026-03-31$3.45bn. XBRL concept us-gaap:Assets. 10-Q filed 2026-04-29, accession 0000874015-26-000177.Report this figure2,995Total assets, Q2 FY2026, at 2026-06-30$2.99bn. XBRL concept us-gaap:Assets. 10-Q filed 2026-07-29, accession 0000874015-26-000251.Report this figure
Current liabilities$m404Current liabilities, Q3 FY2023, at 2023-09-30$404.2m. XBRL concept us-gaap:LiabilitiesCurrent. 10-Q filed 2023-11-02, accession 0000874015-23-000209.Report this figure448Current liabilities, FY2023, at 2023-12-31$448.1m. XBRL concept us-gaap:LiabilitiesCurrent. 10-K filed 2025-02-19, accession 0000874015-25-000089.Report this figure328Current liabilities, Q1 FY2024, at 2024-03-31$327.6m. XBRL concept us-gaap:LiabilitiesCurrent. 10-Q filed 2024-05-07, accession 0000874015-24-000142.Report this figure306Current liabilities, Q2 FY2024, at 2024-06-30$306.2m. XBRL concept us-gaap:LiabilitiesCurrent. 10-Q filed 2024-08-01, accession 0000874015-24-000187.Report this figure305Current liabilities, Q3 FY2024, at 2024-09-30$304.6m. XBRL concept us-gaap:LiabilitiesCurrent. 10-Q filed 2024-11-06, accession 0000874015-24-000232.Report this figure309Current liabilities, FY2024, at 2024-12-31$309.3m. XBRL concept us-gaap:LiabilitiesCurrent. 10-K filed 2026-02-26, accession 0000874015-26-000115.Report this figure250Current liabilities, Q1 FY2025, at 2025-03-31$250.3m. XBRL concept us-gaap:LiabilitiesCurrent. 10-Q filed 2025-04-30, accession 0000874015-25-000123.Report this figure897Current liabilities, period not labelled, at 2025-06-30$897.2m. XBRL concept us-gaap:LiabilitiesCurrent. 10-Q filed 2025-07-30, accession 0000874015-25-000167.Report this figure903Current liabilities, Q3 FY2025, at 2025-09-30$903.5m. XBRL concept us-gaap:LiabilitiesCurrent. 10-Q filed 2025-10-29, accession 0000874015-25-000266.Report this figure782Current liabilities, FY2025, at 2025-12-31$781.6m. XBRL concept us-gaap:LiabilitiesCurrent. 10-Q filed 2026-07-29, accession 0000874015-26-000251.Report this figure717Current liabilities, Q1 FY2026, at 2026-03-31$716.6m. XBRL concept us-gaap:LiabilitiesCurrent. 10-Q filed 2026-04-29, accession 0000874015-26-000177.Report this figure316Current liabilities, Q2 FY2026, at 2026-06-30$315.6m. XBRL concept us-gaap:LiabilitiesCurrent. 10-Q filed 2026-07-29, accession 0000874015-26-000251.Report this figure
Total liabilities$m2,619Total liabilities, Q3 FY2023, at 2023-09-30$2.62bn. XBRL concept us-gaap:Liabilities. 10-Q filed 2023-11-02, accession 0000874015-23-000209.Report this figure2,603Total liabilities, FY2023, at 2023-12-31$2.60bn. XBRL concept us-gaap:Liabilities. 10-K filed 2025-02-19, accession 0000874015-25-000089.Report this figure2,467Total liabilities, Q1 FY2024, at 2024-03-31$2.47bn. XBRL concept us-gaap:Liabilities. 10-Q filed 2024-05-07, accession 0000874015-24-000142.Report this figure2,427Total liabilities, Q2 FY2024, at 2024-06-30$2.43bn. XBRL concept us-gaap:Liabilities. 10-Q filed 2024-08-01, accession 0000874015-24-000187.Report this figure2,419Total liabilities, Q3 FY2024, at 2024-09-30$2.42bn. XBRL concept us-gaap:Liabilities. 10-Q filed 2024-11-06, accession 0000874015-24-000232.Report this figure2,415Total liabilities, FY2024, at 2024-12-31$2.42bn. XBRL concept us-gaap:Liabilities. 10-K filed 2026-02-26, accession 0000874015-26-000115.Report this figure2,337Total liabilities, Q1 FY2025, at 2025-03-31$2.34bn. XBRL concept us-gaap:Liabilities. 10-Q filed 2025-04-30, accession 0000874015-25-000123.Report this figure2,353Total liabilities, period not labelled, at 2025-06-30$2.35bn. XBRL concept us-gaap:Liabilities. 10-Q filed 2025-07-30, accession 0000874015-25-000167.Report this figure2,415Total liabilities, Q3 FY2025, at 2025-09-30$2.42bn. XBRL concept us-gaap:Liabilities. 10-Q filed 2025-10-29, accession 0000874015-25-000266.Report this figure3,035Total liabilities, FY2025, at 2025-12-31$3.03bn. XBRL concept us-gaap:Liabilities. 10-Q filed 2026-07-29, accession 0000874015-26-000251.Report this figure2,959Total liabilities, Q1 FY2026, at 2026-03-31$2.96bn. XBRL concept us-gaap:Liabilities. 10-Q filed 2026-04-29, accession 0000874015-26-000177.Report this figure2,555Total liabilities, Q2 FY2026, at 2026-06-30$2.55bn. XBRL concept us-gaap:Liabilities. 10-Q filed 2026-07-29, accession 0000874015-26-000251.Report this figure
Long-term debt$mnot reported1,241Long-term debt, FY2023, at 2023-12-31$1.24bn. XBRL concept us-gaap:LongTermDebtNoncurrent. 10-K filed 2024-02-21, accession 0000874015-24-000116.Report this figurenot reportednot reportednot reported1,202Long-term debt, FY2024, at 2024-12-31$1.20bn. XBRL concept us-gaap:LongTermDebtNoncurrent. 10-K filed 2025-02-19, accession 0000874015-25-000089.Report this figurenot reportednot reportednot reported1,328Long-term debt, FY2025, at 2025-12-31$1.33bn. XBRL concept us-gaap:LongTermDebtNoncurrent. 10-K filed 2026-02-26, accession 0000874015-26-000115.Report this figurenot reportednot reported
Current portion of debt$mnot reported0.2Current portion of debt, FY2023, at 2023-12-31$157.0k. XBRL concept us-gaap:LongTermDebtCurrent. 10-K filed 2024-02-21, accession 0000874015-24-000116.Report this figurenot reportednot reportednot reported0.2Current portion of debt, FY2024, at 2024-12-31$165.0k. XBRL concept us-gaap:LongTermDebtCurrent. 10-K filed 2025-02-19, accession 0000874015-25-000089.Report this figurenot reportednot reportednot reported432Current portion of debt, FY2025, at 2025-12-31$432.1m. XBRL concept us-gaap:LongTermDebtCurrent. 10-K filed 2026-02-26, accession 0000874015-26-000115.Report this figurenot reportednot reported
Shareholders' equity$m315Shareholders' equity, Q3 FY2023, at 2023-09-30$315.5m. XBRL concept us-gaap:StockholdersEquity. 10-Q filed 2024-11-06, accession 0000874015-24-000232.Report this figure387Shareholders' equity, FY2023, at 2023-12-31$386.7m. XBRL concept us-gaap:StockholdersEquity. 10-K filed 2026-02-26, accession 0000874015-26-000115.Report this figure297Shareholders' equity, Q1 FY2024, at 2024-03-31$296.5m. XBRL concept us-gaap:StockholdersEquity. 10-Q filed 2025-07-30, accession 0000874015-25-000167.Report this figure264Shareholders' equity, Q2 FY2024, at 2024-06-30$263.7m. XBRL concept us-gaap:StockholdersEquity. 10-Q filed 2025-10-29, accession 0000874015-25-000266.Report this figure662Shareholders' equity, Q3 FY2024, at 2024-09-30$662.5m. XBRL concept us-gaap:StockholdersEquity. 10-Q filed 2025-10-29, accession 0000874015-25-000266.Report this figure588Shareholders' equity, FY2024, at 2024-12-31$588.4m. XBRL concept us-gaap:StockholdersEquity. 10-Q filed 2026-07-29, accession 0000874015-26-000251.Report this figure476Shareholders' equity, Q1 FY2025, at 2025-03-31$475.7m. XBRL concept us-gaap:StockholdersEquity. 10-Q filed 2026-07-29, accession 0000874015-26-000251.Report this figure632Shareholders' equity, period not labelled, at 2025-06-30$631.7m. XBRL concept us-gaap:StockholdersEquity. 10-Q filed 2026-07-29, accession 0000874015-26-000251.Report this figure618Shareholders' equity, Q3 FY2025, at 2025-09-30$618.0m. XBRL concept us-gaap:StockholdersEquity. 10-Q filed 2025-10-29, accession 0000874015-25-000266.Report this figure489Shareholders' equity, FY2025, at 2025-12-31$489.1m. XBRL concept us-gaap:StockholdersEquity. 10-Q filed 2026-07-29, accession 0000874015-26-000251.Report this figure491Shareholders' equity, Q1 FY2026, at 2026-03-31$491.4m. XBRL concept us-gaap:StockholdersEquity. 10-Q filed 2026-07-29, accession 0000874015-26-000251.Report this figure440Shareholders' equity, Q2 FY2026, at 2026-06-30$439.7m. XBRL concept us-gaap:StockholdersEquity. 10-Q filed 2026-07-29, accession 0000874015-26-000251.Report this figure

Cash flow

Operating cash flow$565.5m, Q2 FY2026
Capital expenditure$16.1m, Q2 FY2026
Ionis Pharmaceuticals Inc, cash flow, quarterly
Line itemUnitQ3 FY20232023-09-30Q4 FY20232023-12-31Q1 FY20242024-03-31Q2 FY20242024-06-30Q3 FY20242024-09-30Q4 FY20242024-12-31Q1 FY20252025-03-31period not labelled2025-06-30Q3 FY20252025-09-30Q4 FY20252025-12-31Q1 FY20262026-03-31Q2 FY20262026-06-30
Operating cash flow$m(109)Operating cash flow, Q3 FY2023, three months to 2023-09-30−$109.0m. XBRL concept us-gaap:NetCashProvidedByUsedInOperatingActivities. 10-Q filed 2024-11-06, accession 0000874015-24-000232. Derived: 9-month figure less the 6-month figure.Report this figure32.9Operating cash flow, Q4 FY2023, three months to 2023-12-31$32.9m. XBRL concept us-gaap:NetCashProvidedByUsedInOperatingActivities. 10-K filed 2026-02-26, accession 0000874015-26-000115. Derived: 12-month figure less the 9-month figure.Report this figure(150)Operating cash flow, Q1 FY2024, three months to 2024-03-31−$149.9m. XBRL concept us-gaap:NetCashProvidedByUsedInOperatingActivities. 10-Q filed 2025-04-30, accession 0000874015-25-000123.Report this figure(120)Operating cash flow, Q2 FY2024, three months to 2024-06-30−$119.9m. XBRL concept us-gaap:NetCashProvidedByUsedInOperatingActivities. 10-Q filed 2025-07-30, accession 0000874015-25-000167. Derived: 6-month figure less the 3-month figure.Report this figure(115)Operating cash flow, Q3 FY2024, three months to 2024-09-30−$115.0m. XBRL concept us-gaap:NetCashProvidedByUsedInOperatingActivities. 10-Q filed 2025-10-29, accession 0000874015-25-000266. Derived: 9-month figure less the 6-month figure.Report this figure(116)Operating cash flow, Q4 FY2024, three months to 2024-12-31−$116.1m. XBRL concept us-gaap:NetCashProvidedByUsedInOperatingActivities. 10-K filed 2026-02-26, accession 0000874015-26-000115. Derived: 12-month figure less the 9-month figure.Report this figure(151)Operating cash flow, Q1 FY2025, three months to 2025-03-31−$150.8m. XBRL concept us-gaap:NetCashProvidedByUsedInOperatingActivities. 10-Q filed 2026-04-29, accession 0000874015-26-000177.Report this figure151Operating cash flow, period not labelled, three months to 2025-06-30$151.3m. XBRL concept us-gaap:NetCashProvidedByUsedInOperatingActivities. 10-Q filed 2026-07-29, accession 0000874015-26-000251. Derived: 6-month figure less the 3-month figure.Report this figure(131)Operating cash flow, Q3 FY2025, three months to 2025-09-30−$131.4m. XBRL concept us-gaap:NetCashProvidedByUsedInOperatingActivities. 10-Q filed 2025-10-29, accession 0000874015-25-000266. Derived: 9-month figure less the 6-month figure.Report this figure(138)Operating cash flow, Q4 FY2025, three months to 2025-12-31−$137.7m. XBRL concept us-gaap:NetCashProvidedByUsedInOperatingActivities. 10-K filed 2026-02-26, accession 0000874015-26-000115. Derived: 12-month figure less the 9-month figure.Report this figure(793)Operating cash flow, Q1 FY2026, three months to 2026-03-31−$792.8m. XBRL concept us-gaap:NetCashProvidedByUsedInOperatingActivities. 10-Q filed 2026-04-29, accession 0000874015-26-000177.Report this figure566Operating cash flow, Q2 FY2026, three months to 2026-06-30$565.5m. XBRL concept us-gaap:NetCashProvidedByUsedInOperatingActivities. 10-Q filed 2026-07-29, accession 0000874015-26-000251. Derived: 6-month figure less the 3-month figure.Report this figure
Capital expenditure$m2.1Capital expenditure, Q3 FY2023, three months to 2023-09-30$2.1m. XBRL concept us-gaap:PaymentsToAcquirePropertyPlantAndEquipment. 10-Q filed 2024-11-06, accession 0000874015-24-000232. Derived: 9-month figure less the 6-month figure.Report this figure(0.8)Capital expenditure, Q4 FY2023, three months to 2023-12-31−$819.0k. XBRL concept us-gaap:PaymentsToAcquirePropertyPlantAndEquipment. 10-K filed 2026-02-26, accession 0000874015-26-000115. Derived: 12-month figure less the 9-month figure.Report this figure4.5Capital expenditure, Q1 FY2024, three months to 2024-03-31$4.5m. XBRL concept us-gaap:PaymentsToAcquirePropertyPlantAndEquipment. 10-Q filed 2025-04-30, accession 0000874015-25-000123.Report this figure6.2Capital expenditure, Q2 FY2024, three months to 2024-06-30$6.2m. XBRL concept us-gaap:PaymentsToAcquirePropertyPlantAndEquipment. 10-Q filed 2025-07-30, accession 0000874015-25-000167. Derived: 6-month figure less the 3-month figure.Report this figure9.1Capital expenditure, Q3 FY2024, three months to 2024-09-30$9.1m. XBRL concept us-gaap:PaymentsToAcquirePropertyPlantAndEquipment. 10-Q filed 2025-10-29, accession 0000874015-25-000266. Derived: 9-month figure less the 6-month figure.Report this figure25.5Capital expenditure, Q4 FY2024, three months to 2024-12-31$25.5m. XBRL concept us-gaap:PaymentsToAcquirePropertyPlantAndEquipment. 10-K filed 2026-02-26, accession 0000874015-26-000115. Derived: 12-month figure less the 9-month figure.Report this figure12.6Capital expenditure, Q1 FY2025, three months to 2025-03-31$12.6m. XBRL concept us-gaap:PaymentsToAcquirePropertyPlantAndEquipment. 10-Q filed 2026-04-29, accession 0000874015-26-000177.Report this figure12.3Capital expenditure, period not labelled, three months to 2025-06-30$12.3m. XBRL concept us-gaap:PaymentsToAcquirePropertyPlantAndEquipment. 10-Q filed 2026-07-29, accession 0000874015-26-000251. Derived: 6-month figure less the 3-month figure.Report this figure5.3Capital expenditure, Q3 FY2025, three months to 2025-09-30$5.3m. XBRL concept us-gaap:PaymentsToAcquirePropertyPlantAndEquipment. 10-Q filed 2025-10-29, accession 0000874015-25-000266. Derived: 9-month figure less the 6-month figure.Report this figure21.3Capital expenditure, Q4 FY2025, three months to 2025-12-31$21.3m. XBRL concept us-gaap:PaymentsToAcquirePropertyPlantAndEquipment. 10-K filed 2026-02-26, accession 0000874015-26-000115. Derived: 12-month figure less the 9-month figure.Report this figure21.8Capital expenditure, Q1 FY2026, three months to 2026-03-31$21.8m. XBRL concept us-gaap:PaymentsToAcquirePropertyPlantAndEquipment. 10-Q filed 2026-04-29, accession 0000874015-26-000177.Report this figure16.1Capital expenditure, Q2 FY2026, three months to 2026-06-30$16.1m. XBRL concept us-gaap:PaymentsToAcquirePropertyPlantAndEquipment. 10-Q filed 2026-07-29, accession 0000874015-26-000251. Derived: 6-month figure less the 3-month figure.Report this figure
Share repurchases$mnot reportednot reportednot reportednot reportednot reportednot reportednot reportednot reportednot reportednot reportednot reportednot reported

Shares

Diluted shares (weighted)165.42m, Q2 FY2026
Ionis Pharmaceuticals Inc, shares, quarterly
Line itemUnitQ3 FY20222022-09-30Q1 FY20232023-03-31Q2 FY20232023-06-30Q3 FY20232023-09-30Q1 FY20242024-03-31Q2 FY20242024-06-30Q3 FY20242024-09-30Q1 FY20252025-03-31period not labelled2025-06-30Q3 FY20252025-09-30Q1 FY20262026-03-31Q2 FY20262026-06-30
Diluted shares (weighted)m shares142Diluted shares (weighted), Q3 FY2022, three months to 2022-09-30141,950,000 shares. XBRL concept us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding. 10-Q filed 2023-11-02, accession 0000874015-23-000209.Report this figure143Diluted shares (weighted), Q1 FY2023, three months to 2023-03-31142,735,000 shares. XBRL concept us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding. 10-Q filed 2024-05-07, accession 0000874015-24-000142.Report this figure143Diluted shares (weighted), Q2 FY2023, three months to 2023-06-30143,098,000 shares. XBRL concept us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding. 10-Q filed 2024-08-01, accession 0000874015-24-000187.Report this figure143Diluted shares (weighted), Q3 FY2023, three months to 2023-09-30143,317,000 shares. XBRL concept us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding. 10-Q filed 2024-11-06, accession 0000874015-24-000232.Report this figure146Diluted shares (weighted), Q1 FY2024, three months to 2024-03-31145,538,000 shares. XBRL concept us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding. 10-Q filed 2025-04-30, accession 0000874015-25-000123.Report this figure146Diluted shares (weighted), Q2 FY2024, three months to 2024-06-30145,958,000 shares. XBRL concept us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding. 10-Q filed 2025-07-30, accession 0000874015-25-000167.Report this figure149Diluted shares (weighted), Q3 FY2024, three months to 2024-09-30148,593,000 shares. XBRL concept us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding. 10-Q filed 2025-10-29, accession 0000874015-25-000266.Report this figure159Diluted shares (weighted), Q1 FY2025, three months to 2025-03-31158,735,000 shares. XBRL concept us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding. 10-Q filed 2026-04-29, accession 0000874015-26-000177.Report this figure182Diluted shares (weighted), period not labelled, three months to 2025-06-30182,331,000 shares. XBRL concept us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding. 10-Q filed 2026-07-29, accession 0000874015-26-000251.Report this figure160Diluted shares (weighted), Q3 FY2025, three months to 2025-09-30159,765,000 shares. XBRL concept us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding. 10-Q filed 2025-10-29, accession 0000874015-25-000266.Report this figure165Diluted shares (weighted), Q1 FY2026, three months to 2026-03-31164,874,000 shares. XBRL concept us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding. 10-Q filed 2026-04-29, accession 0000874015-26-000177.Report this figure165Diluted shares (weighted), Q2 FY2026, three months to 2026-06-30165,419,000 shares. XBRL concept us-gaap:WeightedAverageNumberOfDilutedSharesOutstanding. 10-Q filed 2026-07-29, accession 0000874015-26-000251.Report this figure

Shares outstanding: 166.18mShares outstanding, period not labelled, at 2026-07-23166,184,322 shares. XBRL concept dei:EntityCommonStockSharesOutstanding. 10-Q filed 2026-07-29, accession 0000874015-26-000251.Report this figure at Jul 23, 2026, from the cover of the 10-Q filed Jul 29, 2026.

Source: SEC EDGAR, XBRL company facts. Last ingested by Listed: Oct 24, 2026, 15:26 ET. Listed shows no prices and gives no investment advice.