Listed

Pyxis Oncology, Inc.

PYXSNasdaqCIK 1782223HealthcareFiscal year ends Dec 31

Latest reported revenue, Q4 FY2025$11.0mRevenue, Q4 FY2025, three months to 2025-12-31$11.0m. XBRL concept us-gaap:Revenues. 10-K filed 2026-03-23, accession 0001193125-26-118532. Derived: 12-month figure less the 9-month figure.Report this figureThree months to Dec 31, 2025, from the 10-K filed Mar 23, 2026.

Latest quarter: Q2 FY2026

Three months to Jun 30, 2026, against the same quarter a year earlier.

  • Revenuenot reported (Revenue not reported)No year-earlier figure to compare
  • Gross marginnot reported (Gross profit and Revenue not reported)No year-earlier figure to compare
  • Operating marginnot reported (Revenue not reported)No year-earlier figure to compare
  • Net marginnot reported (Revenue not reported)No year-earlier figure to compare
  • Diluted EPS−$0.40Diluted EPS, Q2 FY2026, three months to 2026-06-30−$0.40 per share. XBRL concept us-gaap:EarningsPerShareDiluted. 10-Q filed 2026-08-13, accession 0001193125-26-347913.Report this figure−33.3% on a year earlier
  • Free cash flownot reported (Capital expenditure not reported)No year-earlier figure to compare

Last eight quarters

Full statements
Revenue$11.0mOperating margin −165.7%
Diluted EPS−$0.40, Q2 FY2026
Free cash flow−$10.4m, Q4 FY2025
Pyxis Oncology, Inc., key figures for the last eight quarters
Line itemUnitQ3 FY20242024-09-30Q4 FY20242024-12-31Q1 FY20252025-03-31Q2 FY20252025-06-30Q3 FY20252025-09-30Q4 FY20252025-12-31Q1 FY20262026-03-31Q2 FY20262026-06-30Shape over the periods
Revenue$m0.0Revenue, Q3 FY2024, three months to 2024-09-30$0. XBRL concept us-gaap:Revenues. 10-Q filed 2025-11-03, accession 0001193125-25-261696. Derived: 9-month figure less the 6-month figure.Report this figure0.0Revenue, Q4 FY2024, three months to 2024-12-31$0. XBRL concept us-gaap:Revenues. 10-K filed 2026-03-23, accession 0001193125-26-118532. Derived: 12-month figure less the 9-month figure.Report this figurenot reported (Revenue not reported)2.8Revenue, Q2 FY2025, three months to 2025-06-30$2.8m. XBRL concept us-gaap:Revenues. 10-Q filed 2025-08-14, accession 0000950170-25-108906.Report this figure0.0Revenue, Q3 FY2025, three months to 2025-09-30$0. XBRL concept us-gaap:Revenues. 10-Q filed 2025-11-03, accession 0001193125-25-261696. Derived: 9-month figure less the 6-month figure.Report this figure11.0Revenue, Q4 FY2025, three months to 2025-12-31$11.0m. XBRL concept us-gaap:Revenues. 10-K filed 2026-03-23, accession 0001193125-26-118532. Derived: 12-month figure less the 9-month figure.Report this figurenot reported (Revenue not reported)not reported (Revenue not reported)
Gross margin%not reported (Gross profit not reported)not reported (Gross profit not reported)not reported (Gross profit and Revenue not reported)not reported (Gross profit not reported)not reported (Gross profit not reported)not reported (Gross profit not reported)not reported (Gross profit and Revenue not reported)not reported (Gross profit and Revenue not reported)
Operating margin%not reported (Revenue of zero not reported)not reported (Revenue of zero not reported)not reported (Revenue not reported)(700.4%)Operating margin, Q2 FY2025, three months to 2025-06-30. operating income / revenueOperating income: −$19.8m. XBRL concept us-gaap:OperatingIncomeLoss. 10-Q filed 2026-08-13, accession 0001193125-26-347913.Revenue: $2.8m. XBRL concept us-gaap:Revenues. 10-Q filed 2025-08-14, accession 0000950170-25-108906.Report this figurenot reported (Revenue of zero not reported)(165.7%)Operating margin, Q4 FY2025, three months to 2025-12-31. operating income / revenueOperating income: −$18.3m. XBRL concept us-gaap:OperatingIncomeLoss. 10-K filed 2026-03-23, accession 0001193125-26-118532. Derived: 12-month figure less the 9-month figure.Revenue: $11.0m. XBRL concept us-gaap:Revenues. 10-K filed 2026-03-23, accession 0001193125-26-118532. Derived: 12-month figure less the 9-month figure.Report this figurenot reported (Revenue not reported)not reported (Revenue not reported)
Net margin%not reported (Revenue of zero not reported)not reported (Revenue of zero not reported)not reported (Revenue not reported)(650.9%)Net margin, Q2 FY2025, three months to 2025-06-30. net income / revenueNet income: −$18.4m. XBRL concept us-gaap:NetIncomeLoss. 10-Q filed 2026-08-13, accession 0001193125-26-347913.Revenue: $2.8m. XBRL concept us-gaap:Revenues. 10-Q filed 2025-08-14, accession 0000950170-25-108906.Report this figurenot reported (Revenue of zero not reported)(164.0%)Net margin, Q4 FY2025, three months to 2025-12-31. net income / revenueNet income: −$18.1m. XBRL concept us-gaap:NetIncomeLoss. 10-K filed 2026-03-23, accession 0001193125-26-118532. Derived: 12-month figure less the 9-month figure.Revenue: $11.0m. XBRL concept us-gaap:Revenues. 10-K filed 2026-03-23, accession 0001193125-26-118532. Derived: 12-month figure less the 9-month figure.Report this figurenot reported (Revenue not reported)not reported (Revenue not reported)
Diluted EPS$ per share(0.35)Diluted EPS, Q3 FY2024, three months to 2024-09-30−$0.35 per share. XBRL concept us-gaap:EarningsPerShareDiluted. 10-Q filed 2025-11-03, accession 0001193125-25-261696.Report this figurenot reported (Diluted EPS not reported)(0.35)Diluted EPS, Q1 FY2025, three months to 2025-03-31−$0.35 per share. XBRL concept us-gaap:EarningsPerShareDiluted. 10-Q filed 2026-05-14, accession 0001193125-26-222843.Report this figure(0.30)Diluted EPS, Q2 FY2025, three months to 2025-06-30−$0.30 per share. XBRL concept us-gaap:EarningsPerShareDiluted. 10-Q filed 2026-08-13, accession 0001193125-26-347913.Report this figure(0.35)Diluted EPS, Q3 FY2025, three months to 2025-09-30−$0.35 per share. XBRL concept us-gaap:EarningsPerShareDiluted. 10-Q filed 2025-11-03, accession 0001193125-25-261696.Report this figurenot reported (Diluted EPS not reported)(0.37)Diluted EPS, Q1 FY2026, three months to 2026-03-31−$0.37 per share. XBRL concept us-gaap:EarningsPerShareDiluted. 10-Q filed 2026-05-14, accession 0001193125-26-222843.Report this figure(0.40)Diluted EPS, Q2 FY2026, three months to 2026-06-30−$0.40 per share. XBRL concept us-gaap:EarningsPerShareDiluted. 10-Q filed 2026-08-13, accession 0001193125-26-347913.Report this figure
Free cash flow$m(14.7)Free cash flow, Q3 FY2024, three months to 2024-09-30. operating cash flow − capital expenditureOperating cash flow: −$14.7m. XBRL concept us-gaap:NetCashProvidedByUsedInOperatingActivities. 10-Q filed 2025-11-03, accession 0001193125-25-261696. Derived: 9-month figure less the 6-month figure.Capital expenditure: $0. XBRL concept us-gaap:PaymentsToAcquirePropertyPlantAndEquipment. 10-Q filed 2025-11-03, accession 0001193125-25-261696. Derived: 9-month figure less the 6-month figure.Report this figure(19.3)Free cash flow, Q4 FY2024, three months to 2024-12-31. operating cash flow − capital expenditureOperating cash flow: −$19.3m. XBRL concept us-gaap:NetCashProvidedByUsedInOperatingActivities. 10-K filed 2026-03-23, accession 0001193125-26-118532. Derived: 12-month figure less the 9-month figure.Capital expenditure: $0. XBRL concept us-gaap:PaymentsToAcquirePropertyPlantAndEquipment. 10-K filed 2026-03-23, accession 0001193125-26-118532. Derived: 12-month figure less the 9-month figure.Report this figurenot reported (Capital expenditure not reported)not reported (Capital expenditure not reported)not reported (Capital expenditure not reported)(10.4)Free cash flow, Q4 FY2025, three months to 2025-12-31. operating cash flow − capital expenditureOperating cash flow: −$10.4m. XBRL concept us-gaap:NetCashProvidedByUsedInOperatingActivities. 10-K filed 2026-03-23, accession 0001193125-26-118532. Derived: 12-month figure less the 9-month figure.Capital expenditure: $0. XBRL concept us-gaap:PaymentsToAcquirePropertyPlantAndEquipment. 10-K filed 2026-03-23, accession 0001193125-26-118532. Derived: 12-month figure less the 9-month figure.Report this figurenot reported (Capital expenditure not reported)not reported (Capital expenditure not reported)

Focus or hover a figure to see its XBRL concept, period and filing; each links to that filing. A figure marked d is derived: a quarter computed from year-to-date figures, such as the fourth quarter as the fiscal year less the nine months before it. A ratio reads not reported when any input is missing.

Last five fiscal years

Revenue$13.9mOperating margin −609.2%
Diluted EPS−$1.28, FY2025
Free cash flow−$63.5m, FY2025
Pyxis Oncology, Inc., key figures for the last five fiscal years
Line itemUnitFY20212021-12-31FY20222022-12-31FY20232023-12-31FY20242024-12-31FY20252025-12-31Shape over the periods
Revenue$mnot reported (Revenue not reported)not reported (Revenue not reported)not reported (Revenue not reported)16.1Revenue, FY2024, twelve months to 2024-12-31$16.1m. XBRL concept us-gaap:Revenues. 10-K filed 2026-03-23, accession 0001193125-26-118532.Report this figure13.9Revenue, FY2025, twelve months to 2025-12-31$13.9m. XBRL concept us-gaap:Revenues. 10-K filed 2026-03-23, accession 0001193125-26-118532.Report this figure
Gross margin%not reported (Gross profit and Revenue not reported)not reported (Gross profit and Revenue not reported)not reported (Gross profit and Revenue not reported)not reported (Gross profit not reported)not reported (Gross profit not reported)
Operating margin%not reported (Revenue not reported)not reported (Revenue not reported)not reported (Revenue not reported)(554.1%)Operating margin, FY2024, twelve months to 2024-12-31. operating income / revenueOperating income: −$89.5m. XBRL concept us-gaap:OperatingIncomeLoss. 10-K filed 2026-03-23, accession 0001193125-26-118532.Revenue: $16.1m. XBRL concept us-gaap:Revenues. 10-K filed 2026-03-23, accession 0001193125-26-118532.Report this figure(609.2%)Operating margin, FY2025, twelve months to 2025-12-31. operating income / revenueOperating income: −$84.4m. XBRL concept us-gaap:OperatingIncomeLoss. 10-K filed 2026-03-23, accession 0001193125-26-118532.Revenue: $13.9m. XBRL concept us-gaap:Revenues. 10-K filed 2026-03-23, accession 0001193125-26-118532.Report this figure
Net margin%not reported (Revenue not reported)not reported (Revenue not reported)not reported (Revenue not reported)(478.9%)Net margin, FY2024, twelve months to 2024-12-31. net income / revenueNet income: −$77.3m. XBRL concept us-gaap:NetIncomeLoss. 10-K filed 2026-03-23, accession 0001193125-26-118532.Revenue: $16.1m. XBRL concept us-gaap:Revenues. 10-K filed 2026-03-23, accession 0001193125-26-118532.Report this figure(574.5%)Net margin, FY2025, twelve months to 2025-12-31. net income / revenueNet income: −$79.6m. XBRL concept us-gaap:NetIncomeLoss. 10-K filed 2026-03-23, accession 0001193125-26-118532.Revenue: $13.9m. XBRL concept us-gaap:Revenues. 10-K filed 2026-03-23, accession 0001193125-26-118532.Report this figure
Diluted EPS$ per share(8.95)Diluted EPS, FY2021, twelve months to 2021-12-31−$8.95 per share. XBRL concept us-gaap:EarningsPerShareDiluted. 10-K filed 2023-03-22, accession 0000950170-23-009046.Report this figure(3.65)Diluted EPS, FY2022, twelve months to 2022-12-31−$3.65 per share. XBRL concept us-gaap:EarningsPerShareDiluted. 10-K filed 2024-03-21, accession 0000950170-24-034868.Report this figure(1.85)Diluted EPS, FY2023, twelve months to 2023-12-31−$1.85 per share. XBRL concept us-gaap:EarningsPerShareDiluted. 10-K filed 2025-03-18, accession 0000950170-25-040771.Report this figure(1.32)Diluted EPS, FY2024, twelve months to 2024-12-31−$1.32 per share. XBRL concept us-gaap:EarningsPerShareDiluted. 10-K filed 2026-03-23, accession 0001193125-26-118532.Report this figure(1.28)Diluted EPS, FY2025, twelve months to 2025-12-31−$1.28 per share. XBRL concept us-gaap:EarningsPerShareDiluted. 10-K filed 2026-03-23, accession 0001193125-26-118532.Report this figure
Free cash flow$m(35.9)Free cash flow, FY2021, twelve months to 2021-12-31. operating cash flow − capital expenditureOperating cash flow: −$35.3m. XBRL concept us-gaap:NetCashProvidedByUsedInOperatingActivities. 10-K filed 2023-03-22, accession 0000950170-23-009046.Capital expenditure: $540.0k. XBRL concept us-gaap:PaymentsToAcquirePropertyPlantAndEquipment. 10-K filed 2023-03-22, accession 0000950170-23-009046.Report this figure(95.7)Free cash flow, FY2022, twelve months to 2022-12-31. operating cash flow − capital expenditureOperating cash flow: −$89.3m. XBRL concept us-gaap:NetCashProvidedByUsedInOperatingActivities. 10-K filed 2024-03-21, accession 0000950170-24-034868.Capital expenditure: $6.4m. XBRL concept us-gaap:PaymentsToAcquirePropertyPlantAndEquipment. 10-K filed 2024-03-21, accession 0000950170-24-034868.Report this figure(77.4)Free cash flow, FY2023, twelve months to 2023-12-31. operating cash flow − capital expenditureOperating cash flow: −$70.7m. XBRL concept us-gaap:NetCashProvidedByUsedInOperatingActivities. 10-K filed 2025-03-18, accession 0000950170-25-040771.Capital expenditure: $6.7m. XBRL concept us-gaap:PaymentsToAcquirePropertyPlantAndEquipment. 10-K filed 2025-03-18, accession 0000950170-25-040771.Report this figure(57.9)Free cash flow, FY2024, twelve months to 2024-12-31. operating cash flow − capital expenditureOperating cash flow: −$57.7m. XBRL concept us-gaap:NetCashProvidedByUsedInOperatingActivities. 10-K filed 2026-03-23, accession 0001193125-26-118532.Capital expenditure: $237.0k. XBRL concept us-gaap:PaymentsToAcquirePropertyPlantAndEquipment. 10-K filed 2026-03-23, accession 0001193125-26-118532.Report this figure(63.5)Free cash flow, FY2025, twelve months to 2025-12-31. operating cash flow − capital expenditureOperating cash flow: −$63.5m. XBRL concept us-gaap:NetCashProvidedByUsedInOperatingActivities. 10-K filed 2026-03-23, accession 0001193125-26-118532.Capital expenditure: $9.0k. XBRL concept us-gaap:PaymentsToAcquirePropertyPlantAndEquipment. 10-K filed 2026-03-23, accession 0001193125-26-118532.Report this figure

Focus or hover a figure to see its XBRL concept, period and filing; each links to that filing. A figure marked d is derived: a quarter computed from year-to-date figures, such as the fourth quarter as the fiscal year less the nine months before it. A ratio reads not reported when any input is missing.

Insider purchases and sales

All insider transactions

The last 20 open-market transactions reported on Form 4 (codes P and S). The reported price is the price per share the insider stated on the form: filing data, not a market price.

No open-market purchases or sales by insiders are in coverage from Nov 2024 to Oct 2026.

No open-market purchases or sales by insiders are in coverage for this company.

Funds that report holding it

All funds

From each manager's latest Form 13F, largest reported value first. Reported value is as filed at the quarter end: filing data, not a price. A put or call is an option position, not shares held.

Funds that report holding Pyxis Oncology, Inc.
FundQuarter endedReported valueSharesPut or callChange on the quarter before
GordonMD Global Investments LP2026-06-30$30.2m10,024,909Added+5,903,039
Pfizer Inc2026-06-30$19.5m7,032,770Unchanged
Laurion Capital Management LP2026-06-30$14.8m4,900,888Reduced−96,445
VANGUARD CAPITAL MANAGEMENT LLC2026-06-30$6.2m2,075,997Added+42,487
Atle Fund Management AB2026-06-30$2.9m966,459Added+769,423
BlackRock, Inc.2026-06-30$2.6m867,934Added+79,095
Palo Alto Investors LP2026-06-30$2.6m864,277Reduced−146,233
MARSHALL WACE, LLP2026-06-30$2.5m830,544Added+476,127
RENAISSANCE TECHNOLOGIES LLC2026-06-30$2.3m772,232Reduced−116,448
GEODE CAPITAL MANAGEMENT, LLC2026-06-30$1.8m591,849Reduced−6,272

Recent filings

All 343 filings

Reports and events: 10-K, 10-Q, 8-K, proxy statements and ownership schedules.

Pyxis Oncology, Inc., recent filings
FiledFormWhat it isAccession number
2026-10-2120:27 ETDEF 14AProxy statementPeriod 2026-10-210001193125-26-427882
2026-10-0121:24 ET8-K1.01 Entry into a material agreement; 8.01 Other events; 9.01 Financial statements and exhibits0001437749-26-031767
2026-09-0911:34 ET8-K7.01 Regulation FD disclosure; 8.01 Other events; 9.01 Financial statements and exhibits0001193125-26-385901
2026-09-0811:39 ET8-K5.02 Departure or appointment of officers or directors; 7.01 Regulation FD disclosure; 9.01 Financial statements and exhibits0001193125-26-384386
2026-08-1311:44 ET10-QQuarterly reportPeriod 2026-06-300001193125-26-347913
2026-08-1311:42 ET8-K2.02 Results of operations0001193125-26-347911
2026-07-0220:20 ET8-K1.01 Entry into a material agreement; 3.02 Unregistered sale of equity; 7.01 Regulation FD disclosure0001193125-26-294613
2026-06-1520:22 ET8-K5.07 Shareholder vote results0001193125-26-271137
2026-05-1411:56 ET10-QQuarterly reportPeriod 2026-03-310001193125-26-222843
2026-05-1411:36 ET8-K2.02 Results of operations0001193125-26-222818

Latest annual report

Form 10-K for the fiscal year ended Dec 31, 2025Filed Mar 23, 2026. Its page lists the documents and the extracted sections, such as Business and Risk factors.

Forecast league

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About the filer

CIK
1782223
Tickers
PYXS
Exchange
Nasdaq
SIC code
2834 Pharmaceutical Preparations
Sector
Healthcare
Fiscal year ends
Dec 31
Incorporated in
DE
Filer category
<br>Emerging growth company

Source: SEC EDGAR, XBRL company facts, the filing index and Forms 4. Last ingested by Listed: Oct 24, 2026, 15:47 ET. Listed shows no prices and gives no investment advice.